A5077284054- Cancer Cells and Metastasis
- Immune cells in cancer
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Tree Root and Stability Studies
- High Temperature Alloys and Creep
- Advanced materials and composites
- Force Microscopy Techniques and Applications
- Global Health Workforce Issues
- Medical and Agricultural Research Studies
- Ferroptosis and cancer prognosis
- Cellular and Composite Structures
- Thermal Radiation and Cooling Technologies
- Intermetallics and Advanced Alloy Properties
- Digestive system and related health
- Genetic factors in colorectal cancer
- Bamboo properties and applications
- Thermoregulation and physiological responses
- Advanced ceramic materials synthesis
- Colorectal Cancer Treatments and Studies
- Bacterial biofilms and quorum sensing
- Corrosion Behavior and Inhibition
- Cancer Mechanisms and Therapy
- Medical Research and Treatments
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2023-2025
Universitat de Barcelona
2025
Nanjing University of Science and Technology
2022-2024
Jilin Jianzhu University
2023
University of Alberta
2020
South China University of Technology
2018-2020
Guangzhou Medical University
2020
Guangdong Academy of Medical Sciences
2018-2020
Guangzhou First People's Hospital
2020
Guangdong Provincial People's Hospital
2019-2020
Tumor-induced immunosuppressive microenvironment in which myeloid-derived suppressor cells (MDSCs) plays an important role, remains obstacle for effective oncotherapy currently. Inducing MDSCs into maturation was confirmed as method to reduce the tumor-bearing host's immunosuppression. Traditional Chinese medicines (TCM) possess characteristics of alleviating immunosuppression cancer patients and low toxicity. Jianpi Huayu Decoction (JHD) experienced formula TCM based on theory clinical...
Despite being in the same pathway, mutations of KRAS and BRAF colorectal carcinomas (CRCs) determine distinct progression courses. ZEB1 induces an epithelial-to-mesenchymal transition (EMT) is associated with worse most carcinomas. Using samples from patients CRC, mouse models KrasG12D BrafV600E a Zeb1-deficient mouse, we show that had opposite functions KRAS- BRAF-mutant CRCs. In CRCs, was correlated prognosis higher number larger undifferentiated (mesenchymal or EMT-like) tumors....
At present, there are few studies on the mechanisms underlying postoperative recurrence of liver cancer, and mechanism action miR-602 in tumors is not clear. Our goals were to investigate effects expression Ras-associated domain family 1A (RASSF1A) gene regulation primary recurrent hepatic clarify molecular hepatocellular carcinoma.We constructed a mouse orthotopic tumor model model. We measured levels RASSF1A then analyzed RASSF1A. transiently transfected into cells that stably...
The traditional Chinese medicine formula Jianpi-Huayu (JPHY) has been reported to be effective in the treatment of hepatocellular carcinoma (HCC). However, its underlying mechanism remains unclear. In this article, we employed an orthotopic transplantation model nude mice explore whether JPHY could inhibit development HCC by regulating miR-602, which targets Ras association domain-containing protein 1A (RASSF1A) pathway. SMMC-7721 cells were treated with test RASSF1A gene as mediated miR-602...
Abstract As the demand for sustainable construction practices increases, innovative ideas are being explored of insulated wall panels in contemporary buildings. The butterfly is a remarkable organism that uses thermostatic mechanism to regulate its body temperature. microstructure on surface wing scales responsible reflecting incident light multiple times, extending optical path, and increasing absorption, thus ensuring temperature remains stable. This microstructure, also known as capture...
Objective To investigate the training situation and demands for professional of digestive endoscopy nurses, provide feasibal basis to establish nurse system. Methods Using self-designed nurses demand questionnaire, 97 students were surveyed, who participated in July 2015 Jilin province. Results 100% showed will participate specialist knowledge skills training, 98.97% accept new progress endoscopic specialized subject. Respectively 70.1% 91.8% before or after entering department...
In this paper, the multiangle’s crashworthiness of bionic tubes inspired by cylindrical fibers bamboo vascular bundles as well through-hole structure are studied. A finite element model validated theoretical analysis and drop hammer impact experiments is used to assess optimal core distribution ratio tube at 0°, 10°, 20°, 30° impacts. Finally effects number circular wall thickness on investigated. The results show that has better small angle impacts compared square tubes, l14r6 obtained...
Abstract Microbiologically Influenced Corrosion (MIC) and biofouling are major challenges to operators who manage water systems in the oil & gas other sectors. Key these threats is formation accumulation of biofilms piping due agglomeration both biotic components (e.g. microorganisms such as bacteria, archea extracellular polymeric substances) abiotic materials inorganic solids). These adhere inner pipe wall surfaces, evolve over time depending on surrounding environmental conditions....
MgZn2-type (Hf,Ta)Fe2 with negative thermal expansion during magnetic transition is a good ingredient to prepare zero-thermal-expansion composites. In this paper, we provide basic strategy design such composites through introducing another Laves phase by atomic substitution. Co, Ni, Al and V are selected replace Fe in the (Hf,Ta)Fe2, respectively. The former two elements cause additional MgCu2 (C15) MgZn2 (C14) matrix. induced C15 shows positive expansion, which can compensate of C14 With...