A5070719994- Rheumatoid Arthritis Research and Therapies
- Blood Pressure and Hypertension Studies
- Cardiac Ischemia and Reperfusion
- Systemic Lupus Erythematosus Research
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Cardiovascular and exercise physiology
- Biochemical effects in animals
- Hemodynamic Monitoring and Therapy
- Eicosanoids and Hypertension Pharmacology
- Autoimmune and Inflammatory Disorders Research
- Systemic Sclerosis and Related Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chemokine receptors and signaling
- Muscle Physiology and Disorders
- Spondyloarthritis Studies and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Inflammatory Myopathies and Dermatomyositis
- HIV-related health complications and treatments
- Health and Lifestyle Studies
- Vitamin C and Antioxidants Research
- Proteoglycans and glycosaminoglycans research
- Hormonal Regulation and Hypertension
- Muscle and Compartmental Disorders
- Fatty Acid Research and Health
Universidad de Guadalajara
2007-2025
Departamento de Salud
2022
Irisin stimulates osteoblast differentiation increasing bone mass a decreasing in irisin levels might contribute to osteoporotic fractures inflammatory diseases. To date, there is controverted whether are associated with rheumatoid arthritis (RA). Therefore, we evaluate the association of serum Vertebral Fractures (VFs) women RA.A total 148 RA was included study.Clinical characteristics and risk factors VFs evaluated. For measurement mineral density assessment lumbar spine (AP L1-L4) Femoral...
The therapeutic effects of telmisartan, an angiotensin II receptor antagonist and a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, have been demonstrated in several disorders. It has antioxidant immune response modulator properties shown promising results the treatment ischemia/reperfusion (I/R) lesion. In this study, skeletal muscle (right gastrocnemius muscle) I/R lesion was induced rats different reperfusion times (1 h, 24 72 7-day, 14-day subgroups) were assessed....
Objective The aim of this study was to determine the accuracy Omron HEM-7320-LA with Intelli Wrap technology cuff HEM-FL1 for self-measurement and clinic blood pressure (BP) measurement according European Society Hypertension International Protocol revision 2010. Participants methods evaluation performed in 39 individuals. mean age participants 47.9±14 years; systolic BP 145.2±24.3 mmHg (range: 97–190), diastolic 90.9±12.9 68–120), arm circumference 30.8±4 cm 25–38.5). Results device...
Neuropeptide Y (NPY) is a sympathetic neurotransmitter with effects on the regulation of inflammatory cells. The role NPY autoimmune diseases such as rheumatoid arthritis (RA) not completely understood. Therefore, we evaluate if levels are markers disease activity in RA and there correlation between tumor necrosis factor-alpha (TNF-α), leptin, interleukin 6 (IL-6) levels. Cross-sectional design, including 108 women RA. We assessed by DAS28-ESR (considering active score ≥2.6). Serum anti-CCP2...
Objective . To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients moderate severe rheumatoid arthritis (RA), initiating MTX LEF, genotyped for by PCR-RFLP. Therapeutic was strictly defined: only if achieved remission low disease activity (DAS-28 < 3.2). Results Patients LEF had significant decrement DAS-28 (<mml:math...
Myostatin is a regulator of muscle size. To date, there have been no published studies focusing on the relation between myostin levels and myopenia in rheumatoid arthritis (RA).Evaluate value serum myostatin as biomarker cachexia low skeletal mass (LSMM) RA patients, along with whether high associated to these conditions after adjusting for potential confounders.This cross-sectional study included 161 female patients 72 controls. In group, we assessed several risk factors LSMM cachexia....
Abstract Background Human immunodeficiency virus (HIV) infection is associated with a greater risk of cardiovascular disease (CVD). HIV causes chronic inflammatory state and increases oxidative stress which can cause endothelial dysfunction arterial stiffness. Aortic stiffness measured by carotid femoral-pulse wave velocity (cfPWV) central hemodynamics are independent factors have the prognostic ability for CVD. We assessed cfPWV in young individuals recent diagnosis without antiretroviral...
Several interleukin 6 gene (IL6) polymorphisms are implicated in susceptibility to rheumatoid arthritis (RA). It has not yet been established with certainty if these associated the severe radiographic damage observed some RA patients, particularly those development of joint bone ankylosis (JBA). The objective present study was evaluate association between hands and -174G/C -572G/C IL6 Mexican Mestizo people RA. adults long disease duration (>5 years) were classified into two groups according...
There is a significant rate of therapeutic failure in rheumatoid arthritis (RA) patients treated with leflunomide (LEF). This study investigates the utility values teriflunomide levels (A77 1726) identifying RA who remained moderate or severe disease activity after treatment LEF. In this cross-sectional study, we compared: (a) achieved DAS28-ESR ≤ 3.2, and (b) maintained > 3.2 treatment. ROC curves determined cut-off A77 1726 better performance to identify achieving 3.2. Of 115 LEF, 69 (60%)...
Gluteal and lower extremity hypoplasia with ipsilateral toe brachysyndactyly were noted in a 23‐year‐old woman similarly affected to the only previously reported case of counterpart Poland sequence. Since no neurological deficit was found, electromyographic nerve conduction studies limb normal, we propose vascular origin which would involve external iliac artery supply analogous subclavian disruption upper
Background: Muscle wasting, also known as myopenia, is frequent in rheumatoid arthritis (RA). To date, it still unknown if the failure of pharmacologic therapies increases risk myopenia RA. Objective: identify treatment with conventional synthetic DMARDs (csDMARDs) constitutes an independent factor muscle wasting women Methods: This was a cross-sectional study. We included 277 Assessments RA patients included: clinical, epidemiological, and therapeutic variables. The skeletal index (SMI)...
Background A correct blood pressure (BP) measurement is essential for the diagnosis and control of high BP.
Background and Objectives: According to the Third International Consensus Definitions for Sepsis Septic Shock (Sepsis-3), sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host response infection”. The increased presence of free radicals causes an increase in oxidative stress. Vitamin C essential water-soluble vitamin with antioxidant activity immunoregulatory effects that plays potential role treatment bacterial infections. Our aim was evaluate effectiveness...
The relationship between serum glycoprotein syndecan-1 and disease activity in rheumatoid arthritis (RA) is still unknown. This study aimed to evaluate whether concentrations are associated with moderate/severe activity.
Urinary tract infections (UTIs) constitute one of the main complications in kidney recipients, increasing both morbidity and mortality. Due to resurgence antimicrobial resistance, new prophylactic approaches are being investigated. Nitrofurantoin is an antibiotic from nitrofuran group that effective against several Gram-negative Gram-positive organisms; hence, there has been a its prescription for treating MDR pathogens.
Background: Every year, 1.5 million women worldwide experience menopause and the associated changes that cause disability dysfunction. There are multiple treatments focused on symptoms; hormone replacement therapy (HRT) may be one helps us reduce these changes. Objectives: objective of this work was to assess relationship between skeletal muscle mass bone mineral density in postmenopausal using therapy. Methods: Study design: cross-sectional study. A systematic assessment clinical charts...
Antiphospholipid syndrome (APS) is a prothrombotic condition that can affect both the venous circulation and arterial system. The deep veins of lower extremities cerebral blood flow are most common sites thrombosis, respectively. Skin ulceration gangrene may be associated with an active vasculitis in patients APS. These kinds ulcers considered intractable because healing difficult to achieve. Using steroids as immunesuppressant therapy still basic part managing APS vasculitis. Nevertheless,...
Objective: To evaluate the relationship between carotid stiffness parameters and pulmonary function test in patients with Systemic Sclerosis (SSc) hypertension (PH).Design method: We evaluated arterial by pulse wave velocity (PWV), intima-media thickness, distensibility coefficient distension echotracking (MyLabOne Esaote, NH). Distensibility was calibrated central pressure obtained tonometry. assessed forced vital capacity (FVC), expiratory volume one second (FEV1), diffusing for carbon...
Hypertension is the main independent cardiovascular risk factor. However, there are additional factors that induce organic damage.To assess association between hyperinsulinemia, ventricular hypertrophy and left diastolic function.Seventy-four patients aged 30 to 65 years, with mild or moderate systemic hypertension, overweight obesity normal glucose tolerance curve (GTC), were studied. Serum insulin was measured during GTC. The maximum levels of observed 60 minutes after oral load they...