- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Sleep and Wakefulness Research
- Regulation of Appetite and Obesity
- Immunotherapy and Immune Responses
- Cancer, Stress, Anesthesia, and Immune Response
- Apelin-related biomedical research
- Cytomegalovirus and herpesvirus research
- Cancer Immunotherapy and Biomarkers
- Signaling Pathways in Disease
- Diabetes and associated disorders
- Circadian rhythm and melatonin
- Inflammation biomarkers and pathways
- Vagus Nerve Stimulation Research
- Invertebrate Immune Response Mechanisms
- Sleep and related disorders
Université Paris Cité
2016-2018
Inserm
2010-2018
Centre de Recherche sur l'Inflammation
2018
Institut Paoli-Calmettes
2011
Institut de Neurobiologie de la Méditerranée
2011
Centre de Recherche en Cancérologie de Marseille
2011
Aix-Marseille Université
2011
B and T lymphocyte attenuator (BTLA), like its relative programmed cell death-1 (PD-1), is a receptor that negatively regulates murine activation. However, expression function on human cells currently unknown. We report in this study the of BTLA subsets as well regulation virus-specific during primary CMV infection. expressed CD4(+) different stages differentiation, whereas CD8(+) cells, it found naive progressively downregulated memory differentiated effector-type cells. During infection,...
Abstract The human butyrophilin (BTN) 3 or CD277 molecules belong to the B7 family members and are expressed in various immune cells such as T NK cells. Here, we show that triggering considerably enhances TCR‐induced cytokine production cell proliferation, even when another co‐stimulatory molecule, CD28, is engaged. These CD277‐induced additive functional effects accordance with detection of early T‐cell activation events signaling being increased upon engagement. However, found not involved...