Francesca Manni

ORCID: 0000-0003-0470-2299
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About
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Research Areas
  • Optical Imaging and Spectroscopy Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Artificial Intelligence in Healthcare and Education
  • Medical Imaging and Analysis
  • Infrared Thermography in Medicine
  • Surgical Simulation and Training
  • Privacy-Preserving Technologies in Data
  • Robotics and Sensor-Based Localization
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Machine Learning in Healthcare
  • Explainable Artificial Intelligence (XAI)
  • Augmented Reality Applications
  • Corneal surgery and disorders
  • Artificial Intelligence in Healthcare
  • Photodynamic Therapy Research Studies
  • Scoliosis diagnosis and treatment
  • Advanced Image and Video Retrieval Techniques
  • Optical Coatings and Gratings
  • Remote-Sensing Image Classification
  • Cryptography and Data Security
  • Spinal Fractures and Fixation Techniques
  • Advanced Vision and Imaging
  • Medical Image Segmentation Techniques
  • Advanced Semiconductor Detectors and Materials
  • Advanced Radiotherapy Techniques

Philips (Netherlands)
2022-2024

Eindhoven University of Technology
2018-2024

Philips (India)
2023

Philips (Finland)
2020

Karolinska University Hospital
2020

The primary treatment for malignant brain tumors is surgical resection. While gross total resection improves the prognosis, a supratotal may result in neurological deficits. On other hand, accurate intraoperative identification of tumor boundaries be very difficult, resulting subtotal resections. Histological examination biopsies can used repeatedly to help achieve but this not practically feasible due turn-around time tissue analysis. Therefore, techniques recognize types are investigated...

10.3390/s20236955 article EN cc-by Sensors 2020-12-05

Federated Learning (FL) is a machine learning technique that enables to collaboratively learn valuable information across devices or sites without moving the data. In FL, model trained and shared decentralized locations where data are privately owned. After local training, updates sent back central server, thus enabling access distributed on large scale while maintaining privacy, security, rights. Although FL well-studied topic, existing frameworks still at an early stage of development....

10.1109/jbhi.2022.3185418 article EN IEEE Journal of Biomedical and Health Informatics 2022-06-22

In spinal surgery, surgical navigation is an essential tool for safe intervention, including the placement of pedicle screws without injury to nerves and blood vessels. Commercially available systems typically rely on tracking a dynamic reference frame attached spine patient. However, can be dislodged or obscured during procedure, resulting in loss navigation. Hyperspectral imaging (HSI) captures large number spectral information bands across electromagnetic spectrum, providing image unseen...

10.3390/app10124078 article EN cc-by Applied Sciences 2020-06-12

The most important prognostic factor for the survival of advanced-stage epithelial ovarian cancer (EOC) is completeness cytoreductive surgery (CRS). Therefore, an intraoperative technique to detect microscopic tumors would be great value. aim this pilot study assess feasibility near-infrared hyperspectral imaging (HSI) EOC detection in ex vivo tissue samples. Images were collected during CRS 11 patients wavelength range 665−975 nm, and processed by calibration, normalization, noise...

10.3390/cancers14061422 article EN Cancers 2022-03-10

Surgical navigation systems are increasingly used for complex spine procedures to avoid neurovascular injuries and minimize the risk reoperations. Accurate patient tracking is one of prerequisites optimal motion compensation navigation. Most current optical use dynamic reference frames (DRFs) attached spine, movement tracking. However, itself subject intrinsic movements which can impact accuracy system. In this study, we aimed detect actual features in different image views captured by...

10.3390/s20133641 article EN cc-by Sensors 2020-06-29

Glial tumors grow diffusely in the brain. Survival is correlated to extent of tumor removal, but borders are often invisible. Resection beyond as defined by conventional methods may further improve prognosis. In this proof-of-concept study, we evaluate diffuse reflectance spectroscopy (DRS) for discrimination between glial and normal brain ex vivo. DRS spectra histology were acquired from 22 samples nine tissue retrieved 30 patients. The content biological chromophores scattering features...

10.1364/boe.474344 article EN cc-by Biomedical Optics Express 2022-11-09

The main curative treatment for localized colon cancer is surgical resection. However when tumor residuals are left positive margins found during the histological examinations and additional needed to inhibit recurrence. Hyperspectral imaging (HSI) can offer non-invasive guidance with potential of optimizing effectiveness. In this paper we investigate capability HSI automated detection in six ex-vivo specimens employing a spectral-spatial patch-based classification approach. results...

10.1109/embc44109.2020.9176543 article EN 2020-07-01

Head and neck cancer (HNC) includes cancers in the oral/nasal cavity, pharynx, larynx, etc., it is sixth most common worldwide. The principal treatment surgical removal where a complete tumor resection crucial to reduce recurrence mortality rate. Intraoperative imaging enables surgeons objectively visualize malignant lesion maximize with healthy safe margins. Hyperspectral (HSI) an emerging modality for detection, which can augment inspection, currently limited subjective visual inspection....

10.1117/12.2512238 article EN 2019-03-08

During complex interventions, patient tracking is needed for optimal motion compensation, in order to guide the physician a minimally invasive way. Nowadays, optical systems are used of markers. Despite unobtrusiveness this technology, approach cumbersome because it requires manual placement markers, which can alter during operations due presence liquids. To improve clinical workflow, new feature algorithm designed, involving detection and without The markers created with multispectral...

10.1109/icip.2018.8451263 article EN 2018-09-07

In neurosurgery, technical solutions for visualizing the border between healthy brain and tumor tissue is of great value, since they enable surgeon to achieve gross total resection while minimizing risk damage eloquent areas. By using real-time non-ionizing imaging techniques, such as hyperspectral (HSI), spectral signature analyzed allowing classification, thereby improving boundary discrimination during surgery. More particularly, infrared penetrates deeper in than visible light, use an...

10.1117/12.2548754 article EN 2020-03-16

Abstract Background Minimally invasive spine surgery is dependent on accurate navigation. Computer-assisted navigation increasingly used in minimally (MIS), but current solutions require the use of reference markers surgical field for both patient and instruments tracking. Purpose To improve reliability facilitate clinical workflow, this study proposes a new marker-free tracking framework based skin feature recognition. Methods Maximally Stable Extremal Regions (MSER) Speeded Up Robust...

10.1186/s12938-020-00843-7 article EN cc-by BioMedical Engineering OnLine 2021-01-07

Surgical navigation systems can enhance surgeon vision and form a reliable image-guided tool for complex interventions as spinal surgery. The main prerequisite is successful patient tracking which implies optimal motion compensation. Nowadays, optical satisfy the need of detecting position during surgery, allowing without risk damaging neurovascular structures. However, spine subject to vertebrae movements impact accuracy system. aim this paper investigate feasibility novel approach offering...

10.1109/embc.2019.8856304 article EN 2019-07-01

Surgery is a crucial treatment for malignant brain tumors where gross total resection improves the prognosis. Tissue samples taken during surgery are either subject to preliminary intraoperative histological analysis, or sent full pathological evaluation which can take days weeks. Whereas lengthy complete analysis includes an array of techniques be executed, tissue on frozen performed as quickly possible (30-45 minutes average) provide fast feedback surgeon surgery. The uses information...

10.1117/12.2580158 article EN 2021-02-12

MR-guided high-intensity focused ultrasound (MR-HIFU) is a non-invasive therapeutic technology which has demonstrated clinical potential for tissue ablation. The application of this approach facilitated to be promising option achieve faster pain palliation in patients with bone metastasis. However, its adoption still hampered by lack workflow integration. Currently, ensure sufficient positioning, MR images have repeatedly acquired between patient re-positioning tasks, leading time-consuming...

10.1117/12.2580838 article EN 2021-02-12

<h3>Introduction/Background*</h3> The most important prognostic factor for the survival of advanced-stage ovarian cancer is completeness cytoreductive surgery (CRS). Therefore, an intraoperative technique to detect microscopic tumours would be great value. aim this pilot study assess feasibility near infrared (NIR) hyperspectral imaging (HSI) detection malignant cancer, using ex vivo tissue samples collected during CRS. <h3>Methodology</h3> In pilot-study, patients with proven or suspected...

10.1136/ijgc-2021-esgo.260 article EN Miscellaneous 2021-10-01

Abstract Background : Minimally invasive spine surgery is dependent on accurate navigation. Computer-assisted navigation increasingly used in minimally (MIS), but current solutions require the use of reference markers surgical field for both patient and instruments tracking. Purpose: To improve reliability facilitate clinical workflow, this study proposes a new marker-free tracking framework based skin feature recognition. Methods Maximally Stable Extremal Regions (MSER) Speeded Up Robust...

10.21203/rs.3.rs-87107/v1 preprint EN cc-by Research Square (Research Square) 2020-10-09

10.5281/zenodo.7447362 article Zenodo (CERN European Organization for Nuclear Research) 2022-12-16
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