- Nanoparticles: synthesis and applications
- Analytical chemistry methods development
- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Chromatography
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Groundwater flow and contamination studies
- Microplastics and Plastic Pollution
- Skin Protection and Aging
- Healthcare and Environmental Waste Management
- X-ray Spectroscopy and Fluorescence Analysis
- Chemical and Physical Properties in Aqueous Solutions
- Recycling and Waste Management Techniques
- Electrohydrodynamics and Fluid Dynamics
- Extraction and Separation Processes
- Radioactive element chemistry and processing
- Heavy Metal Exposure and Toxicity
- Chemical Synthesis and Characterization
- Laser-induced spectroscopy and plasma
- Groundwater and Isotope Geochemistry
- Chemistry and Chemical Engineering
- Electron and X-Ray Spectroscopy Techniques
- Advanced Chemical Sensor Technologies
- Air Quality and Health Impacts
- Protein Interaction Studies and Fluorescence Analysis
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2013-2024
Direction de la Recherche Technologique
2023
Université Grenoble Alpes
2015-2023
CEA LITEN
2013-2023
Laboratoire de Mesure du Carbone 14
2021
CEA Grenoble
2011-2019
CEA Paris-Saclay
1998-2000
Centre National de la Recherche Scientifique
1998
CEA Paris-Saclay - Etablissement de Fontenay-aux-roses
1995
St. Jude Children's Research Hospital
1990
Abstract A human serum albumin‐based HPLC chiral stationary phase (HSA‐CSP) has been examined as a tool to investigate binding of drugs HSA and drug–drug protein‐binding interactions. Rac‐oxazepam hemisuccinate (OXH) was used model compound the chromatographic retention ( k ′) its enantiomers determined after addition displacers mobile phase. Compounds known bind at same site OXH different sites were tested for their displacing capacities. Competitive interactions between in reflected by...
Microalgae are good candidates for toxic metal remediation biotechnologies. This study explores the cellular processes implemented by green microalga Coccomyxa actinabiotis to take up and cope with silver over concentration range of 10(-7) 10(-2) M Ag(+). Understanding these enables us assess potential this applications bioremediation. Silver in situ speciation localization were investigated using X-ray absorption spectroscopy, diffraction, transmission electron microscopy. toxicity was...
Acute exposure of A549 cells to Ag-NPs induces stronger effects on DNA integrity, ROS level, cell metabolism and cycle than repeated exposure. dissolves in both conditions Ag ions recombine with thiolated proteins.
The widespread use of silver nanoparticles (Ag NPs) in food and consumer products suggests the relevance human oral exposure to these nanomaterials (NMs) raises possibility adverse effects gastrointestinal tract. aim this study was investigate toxicity Ag NPs a intestinal cell line, either uncoated or coated with polyvinylpyrrolidone PVP) hydroxyethylcellulose HEC) digested simulated fluids. Physicochemical transformations during different stages vitro digestion were identified prior...
Metal oxide nanoparticles were analyzed by ICP-MS with direct injection and their recoveries determined in different media.
Agreements and discrepancies are pointed out in the comparison between spICP-MS, AF4-MALLS-ICP-MS, other routine techniques for nanoparticle sizing. Calibration protocols play an important role analytical result quality.
Direct TXRF analysis of nanoparticles deposited on filters was evaluated. Standard spiked with known amounts NP were produced using an atomizer which generates aerosol from a containing-liquid suspension. Polycarbonate provided the highest fluorescence signals and black polycarbonate containing chromium further selected, Cr being used as internal standard for elemental quantification filter contaminants.