A5043967941- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Palliative Care and End-of-Life Issues
- Renal Transplantation Outcomes and Treatments
- Grief, Bereavement, and Mental Health
- Patient Satisfaction in Healthcare
- Liver Disease and Transplantation
- Prostate Cancer Diagnosis and Treatment
- Healthcare Policy and Management
- Health Systems, Economic Evaluations, Quality of Life
- Health Policy Implementation Science
- Digital Mental Health Interventions
- Psoriasis: Treatment and Pathogenesis
- Parathyroid Disorders and Treatments
- Opioid Use Disorder Treatment
- Patient Safety and Medication Errors
- Autopsy Techniques and Outcomes
- Economic and Financial Impacts of Cancer
- Prostate Cancer Treatment and Research
- Behavioral Health and Interventions
- Bone and Joint Diseases
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Meta-analysis and systematic reviews
- Hip and Femur Fractures
Navitas Systems (United States)
2024
Ottawa Hospital
2017-2022
Ottawa Hospital Research Institute
2017-2022
Western University
2013-2021
University of Ottawa
2021
Institute for Clinical Evaluative Sciences
2017-2020
Lawson Health Research Institute
2017-2019
Stanford University
2018
Quality and Reliability (Greece)
2016
London Health Sciences Centre
2012-2013
Background Cardiovascular death remains the leading cause of mortality in kidney transplant recipients. events are associated with significant morbidity. However, current trends cardiovascular after transplantation poorly understood. Methods We conducted a retrospective study using healthcare databases Ontario, Canada, to determine whether incidence has changed from 1994 2009. Our primary endpoint was 3-year composite outcome posttransplant or major event (myocardial infarction, coronary...
There is a worldwide shortage of organs available for transplant, leading to preventable mortality associated with end-stage organ disease. While most citizens in many countries an intent-to-donate “opt-in” system support donation, registration rates remain low. In Canada, Canadians donation but less than 25% provinces have registered their desire donate when they die. The family physician office promising yet underused setting which promote donor and address known barriers enablers...
Early hospital readmission (EHR) is associated with morbidity, mortality, and significant healthcare costs. However, trends over time in EHR events kidney transplant recipients have not been examined. We conducted a population-based cohort study using linked databases from Ontario, Canada, to determine whether the incidence has changed 2002 2014 recipients.We defined as an unplanned admission for any reason acute care within 30 days of being discharged transplantation; admissions elective...
The purpose of this study was to assess the facilitators and barriers implementation Systemic Falls Investigative Method (SFIM) on selected hospital units.A cross-sectional explanatory mixed methods design used converge results from a standardized safety culture survey with themes that emerged interviews focus groups. Findings were organized by six elements Ottawa Model Research Use framework.A geriatric rehabilitation unit an acute care neurological purposefully due high frequency...
Background The epidemiology of ESRD requiring maintenance dialysis (ESRD-D) in large, diverse immigrant populations is unclear.Methods We estimated ESRD-D prevalence and incidence among immigrants Ontario, Canada. Adults residing Ontario 2014 were categorized as long-term Canadian residents or according to administrative health immigration datasets. determined these adults calculated age-adjusted ratios (PRs) comparing residents. Among those who immigrated between 1991 2012, was by world...
Prior work showed that patients from the CorEvitas Psoriasis Registry who had previously failed a prior biologic and then initiated ixekizumab demonstrated improvements in disease severity patient-reported outcomes after 6 months. However, newer therapies such as interleukin-23 inhibitors (IL-23i) were not considered. Here, with more recent data including IL-23i, 6-month effectiveness of following switch any was assessed well whether impacted by class. We included discontinuing another...
Objective For various reasons, people of Chinese (China, Hong Kong or Taiwan) and South Asian (Indian subcontinent) ancestry (the two largest ethnic minority groups in Ontario, Canada) may be less likely to register for deceased organ donation than the general public, their families consent at time death. Methods We conducted population-based studies: (1) a cross-sectional study donor registration as May 2013, (2) cohort steps proceeding with patients who died hospital from October 2008...
Early hospital readmissions (EHRs) occur commonly in kidney transplant recipients. Conflicting evidence exists regarding risk factors and outcomes of EHRs.To determine associated with EHRs (ie, hospitalization within 30 days discharge from hospitalization) recipients.Population-based cohort study using linked, administrative health care databases.Ontario, Canada.We included 5437 recipients 2002 to 2015.Risk EHRs. We assessed donor, recipient, factors. also the following outcomes: total graft...
Background The Government of Ontario, Canada, announced hospital funding reforms in 2011, including Quality-based Procedures (QBPs) involving pre-set funds for managing patients with specific diagnoses/procedures. A key goal was to improve quality care across the jurisdiction. Methods Interrupted time series evaluated policy change, focusing on four QBPs (congestive heart failure, hip fracture surgery, pneumonia, prostate cancer surgery), hospitalized 2010–2017. Outcomes included return or...
A shortage of organs for transplant has prompted many countries to encourage citizens register ("opt in") donate their and tissues when they die. 1 However, less than 40% the public is registered organ donation in most with a registry. 1One common fear that physicians will not take all measures save life citizen at time illness. 2 Showing are themselves could help dispel this myth.Although surveys support donation, 3 whether actually remains unknown.Methods | We conducted population-based...
In Canada, deceased organ donation provides over 80% of transplanted organs. At the time death, families, friends or others assume responsibility as substitute decision-makers (SDMs) to consent donation. Despite their central role in this process, little is known about what barriers, enablers and beliefs influence decision-making among SDMs. This study aims explore experiences perspectives SDMs involved making decisions around withdrawal life-sustaining therapies, end-of-life care 60...
Objective Increasing deceased organ donation registration may increase the number of available organs for transplant to help save lives. This study aimed identify which behaviour change techniques (BCTs; or ‘active ingredients’) are reported within randomized trials interventions promoting and those, associated with a larger intervention effect. Methods We conducted secondary analysis 45 included in Cochrane systematic review interventions. Two researchers used BCT Taxonomy v1 independently...
Objective We evaluated the validity of physician billing claims to identify deceased organ donors in large provincial healthcare databases. Methods conducted a population-based retrospective validation study all Ontario, Canada from 2006 2011 (n = 988). included registered deaths during same period 458,074). Our main outcome measures sensitivity, specificity, positive predictive value, and negative value various algorithms consisting organ-specific compared reference standard medical chart...
Background: Many families choose not to consent organ donation at the time of their loved one’s death. In Ontario, Canada, whether these decisions vary by ethnicity remains unclear. Objective: To compare proportion immigrants who consented for deceased with long-term residents. Design: Population-based retrospective cohort study. Setting: Potential donors in between November 2008 and March 2013. Methods: We used linked administrative databases study donation. Results: Overall, 2873 potential...
The shortage of available organs for life-saving transplants persists worldwide. While a majority support donating their or tissue when they die, many have not registered wish to do so. When registered, next kin are much more likely follow-through with the decision donate. In countries, most people visit family physician office each year and this setting is promising, yet underused, site where could register deceased organ donation. Our primary aim was evaluate effectiveness an intervention...
The Kidney Foundation of Canada developed a pilot campaign to educate persons attending junior hockey league games in London, Ontario, Canada, on deceased organ donation.To evaluate the impact number new and tissue donor registrants.Population-based retrospective cohort study.Residents Ontario.We included 255 476 individuals eligible register for donation with Ontario postal code.We compared registrants during period (March 12 April 16, 2015) 3 different time periods (December 30, 2014...