- Lung Cancer Treatments and Mutations
- Head and Neck Cancer Studies
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Multiple Myeloma Research and Treatments
- Lung Cancer Research Studies
- Head and Neck Surgical Oncology
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Iron Metabolism and Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Legal principles and applications
- BRCA gene mutations in cancer
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Sarcoma Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Cytomegalovirus and herpesvirus research
- Esophageal Cancer Research and Treatment
- Chronic Myeloid Leukemia Treatments
- Genetic factors in colorectal cancer
- Hemoglobinopathies and Related Disorders
- Child Nutrition and Water Access
- Thyroid Cancer Diagnosis and Treatment
- Acne and Rosacea Treatments and Effects
NRG Oncology
2022-2024
American College of Radiology
2022-2023
RTOG Foundation
2004-2022
University of Pennsylvania
2004-2022
Maimonides Medical Center
2015-2018
Corporación Universitaria Rafael Nuñez
2018
ORCID
2018
Bellevue Hospital Center
2012
Moffitt Cancer Center
2004-2012
UCSF Helen Diller Family Comprehensive Cancer Center
2012
Purpose Tobacco smoking is associated with oropharynx cancer survival, but to what extent progression or death increases increasing tobacco exposure unknown. Patients and Methods enrolled onto a phase III trial of radiotherapy from 1991 1997 (Radiation Therapy Oncology Group [RTOG] 9003) chemoradiotherapy 2002 2005 (RTOG 0129) were evaluated for tumor human papillomavirus status by surrogate, p16 immunohistochemistry, standardized questionnaire. Associations between overall survival (OS)...
PURPOSE Radiotherapy (RT)/cetuximab (C) demonstrated superiority over RT alone for locally advanced squamous head and neck cancer. We tested this in completely resected, intermediate-risk METHODS Patients had cell carcinoma of the (SCCHN) oral cavity, oropharynx, or larynx, with one more risk factors warranting postoperative RT. were randomly assigned 1:1 to intensity-modulated (60-66 Gy) once-per-week C alone. The primary hypothesis was that + would improve overall survival (OS)...
We reviewed the linear growth and plate morphology in all children with homozygous beta thalassemia followed Toronto, for whom monthly height percentiles were available before, a 36-month period after, initiation of nightly subcutaneous deferoxamine therapy. All patients less than 7 years age when begun on deferoxamine, had received minimum 36 months. Marked abnormalities metaphyseal readily observed distal ulnar, radial, tibial metaphyses 11 37 significant decline mean percentile was also...
<div>AbstractPurpose:<p><i>NFE2L2/KEAP1/CUL3</i> mutations have been validated for radioresistance in cell-based assays and animal models. However, clinical validation of these biomarkers has challenging because multimodality treatment regimens. This study aims to investigate the association between <i>NFE2L2/KEAP1/CUL3</i> patient outcomes, including local failure, locoregional disease-free survival (DFS), overall survival, using samples from a phase III...
<p>Study schema of NRG/RTOG 9512</p>
<p>Analysis of local failure, local-regional disease-free survival and overall survival</p>
Besides an AIDS-defining illness, Kaposi sarcoma (KS) is also seen in individuals on long-term immunosuppressant therapy. We report KS a 70-year-old immunocompetent man, which initially mimicked acute flare of ulcerative colitis (UC). He was hospitalized multiple times for complaints watery diarrhea and tenesmus. Despite treatment with mesalamine, short courses methylprednisolone, one dose infliximab, his symptoms improved only partially. underwent colonoscopy, revealed mild active mass the...
ANCA-associated vasculitis (AAV) is a rare and potentially life threatening complication associated with antithyroid drug use. It more commonly reported propylthiouracil, fewer cases methimazole We present the case of 55-year-old man toxic multinodular goiter which was treated for 6 months. He developed ANCA positive leukocytoclastic hemorrhagic necrotic bullous lesions lower extremities. The initially thought to be secondary recent cephalosporin use; however, skin progressed despite...
Primary effusion lymphoma (PEL) is a rare form of non-Hodgkin that presents with body cavity effusions. It occurs chiefly in immunodeficient HIV-positive patients. The tumor cells generally express gene sequences human herpesvirus-8 (HHV-8) and Epstein-Barr virus (EBV). Tumor HIV-negative patients usually HHV-8 sequences, but rarely those EBV. We report novel case PEL an homosexual male whose expressed both EBV who developed evidence central nervous system involvement.
Adenomyomatous hyperplasia (AH) is commonly found in the gallbladder and considered a tumor-like inflammatory lesion arising from Rokitansky-Aschoff sinus. It extremely rare extrahepatic bile duct only 15 cases have been reported to date. We describe 63-year-old male patient who presented with cholangitis, underwent an extensive diagnostic workup, ultimately had Whipple procedure. Final pathology showed 2.0 × 1.5 0.5 cm3 granular distal common duct. There was prominent biliary epithelial...
A 67-year-old man presented with a 3-day history of abdominal pain, fever, and significant weight loss over 2 months. Physical examination revealed left upper quadrant tenderness, hepatomegaly, splenomegaly, bilateral pitting edema but peripheral lymphadenopathy was absent. Laboratory tests showed anemia, thrombocytopenia, elevated prothrombin time (PT), partial thromboplastin (PTT), increased lactate dehydrogenase (LDH). PTT corrected completely in mixing study. Further workup for the cause...
Burkitt’s lymphoma, a form of non-Hodgkin is neoplastic monoclonal proliferation lymphoid cells in areas the immune system. It can occur HIV-positive patients, as AIDS related to development non- Hodgkin lymphoma. Burkitt's lymphoma rare subtype, highly prevalent patients with AIDS. Incisional biopsy, situ hybridization and computerized axial tomography are appropriate tests determine characterize lesions. The case 4-year-old patient, who developed oral cavity, reported this paper. aim...