- Lipid Membrane Structure and Behavior
- Cellular Mechanics and Interactions
- Photosynthetic Processes and Mechanisms
- Force Microscopy Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- Cardiomyopathy and Myosin Studies
- Neuroscience and Neuropharmacology Research
- Analytical Chemistry and Chromatography
- Electrochemical Analysis and Applications
- Metabolomics and Mass Spectrometry Studies
- Nanopore and Nanochannel Transport Studies
- Ion channel regulation and function
- Advanced Fluorescence Microscopy Techniques
- Cell Adhesion Molecules Research
- Lipid metabolism and biosynthesis
- RNA Interference and Gene Delivery
- Protein Interaction Studies and Fluorescence Analysis
Technische Universität Dresden
2012-2024
University Hospital Carl Gustav Carus
2019-2020
Carl Gustav Carus-Institut
2019
Fluorescence correlation spectroscopy (FCS) measurements are widely used for determination of diffusion coefficients lipids and proteins in biological membranes. In recent years, several variants FCS have been introduced. However, a comprehensive comparison these methods on identical systems has so far lacking. addition, there exist no consistent values already determined well-known or membrane systems. This study aims to contribute better comparability experiments membranes by determining...
F-actin binding and bundling are crucial to a plethora of cell processes, including morphogenesis, migration, adhesion many others. SWAP-70 was recently described as an
Dynamic rearrangements of the F-actin cytoskeleton are a hallmark tumor metastasis. Thus, proteins that govern major interest for understanding metastasis and potential therapies. We hypothesized unique binding bundling protein SWAP-70 contributes importantly to Orthotopic, ectopic, short-term tail vein injection mouse breast lung cancer models revealed strong positive dependence bone on SWAP-70. Breast cell growth, migration, adhesion, invasion assays SWAP-70’s key role in these...