A5102781665- Gastrointestinal Tumor Research and Treatment
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Gastric Cancer Management and Outcomes
- Chronic Lymphocytic Leukemia Research
- Potassium and Related Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Testicular diseases and treatments
- Erythropoietin and Anemia Treatment
- Urological Disorders and Treatments
- Systemic Sclerosis and Related Diseases
- Renal Diseases and Glomerulopathies
- Hemoglobinopathies and Related Disorders
- Diagnosis and Treatment of Venous Diseases
- Muscle and Compartmental Disorders
- Neurofibromatosis and Schwannoma Cases
- Metastasis and carcinoma case studies
- Dermatologic Treatments and Research
- Autoimmune Neurological Disorders and Treatments
- Genetic and Kidney Cyst Diseases
- Animal Virus Infections Studies
- Parathyroid Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Electrolyte and hormonal disorders
Saga University
2016-2023
National Hospital
1989
The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab is a low-density lipoprotein (LDL)-lowering drug with new mechanism, which currently available in Japan. Here, for the first time, we report successful use of PCSK9 patient refractory nephrotic syndrome. A 61-year-old woman was diagnosed minimal change-type syndrome October 2012. She received prednisolone (PSL) and cyclosporin (CyA), but she experienced several cycles relapse remission hospitalized May 2016 due to...
Concerns about sodium overload when using polystyrene sulfonate (Na-resin) as an ion-exchange resin for the treatment of hyperkalemia led our institution to gradually shift use calcium (Ca-resin). However, serum potassium levels were insufficiently controlled and patients experienced constipation, we returned Na-resin observed better results than previously.As few papers have examined adsorption ability Ca-resin compared with Na-resin, investigated this issue within institution.We studied in...
10015 Background: Patients with GIST resistant to both imatinib (IM) and sunitinib (SU) have a poor prognosis few therapeutic options. The objective of this study is investigate efficacy safety nilotinib as third line therapy for Japanese pts who shown resistance and/or intolerance sunitinib. Methods: A single arm, open-label trial was conducted in 8 hospitals Japan. key eligibility criteria included histologically confirmed KIT-positive progression on or treatment. Pts were treated 400 mg...
Various factors are considered to be mechanisms of the increase in sizes cysts patients with polycystic kidney disease. Vasopressin is one causes, and drinking large volumes water shows an effect suppressing cysts. On other hand, it known that hydrogen-rich reduces oxidative stress has a good on injury. We examined whether affected Forty 5-week-old PCK rats were randomly assigned four groups: C(Control), purified water; W(Water), sugar; H(Hydrogen), WH(Water+Hydrogen), sugar. They consumed...
A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, rheumatoid factor. He negative anti-hepatitis C virus antibodies. pathological analysis the renal tissue membranoproliferative glomerulonephritis, common histological features cryoglobulinemic vasculitis (CV),...
High-dose erythropoietin (EPO) administration to hemodialysis (HD) patients with EPO hyporesponsiveness, due iron deficiency, hyperparathyroidism, malnutrition, inflammation, and inadequate HD, results in increased risk of mortality cardiovascular events. We investigated the relationship dose requirement 4-, 5-, 6-hour HD treatment times.This cross-sectional study enrolled 300 patients, including those on 4-hour (n = 78), 5-hour 106), 116). studied following parameters: weekly dose,...
Elevated creatinine concentrations often indicate acute renal injury and biopsies are considered in this situation. However,pseudohypercreatininemia is potential cause of elevated concentrations, invasive interventions should be avoided.A 54-year-old woman underwent surgery for descending aortic dissection.Nine days postoperatively, her concentration increased from 1 mg/dl to 5.78 (normal range, 0.47-0.7 mg/dl). Azotemia hyperkalemia were absent physical examination findings unremarkable....
26歳女性, 米国人. 1年前にALT (Assistant Language Teacher) として来日した. 頭痛と嘔気で前医を受診し, 急性腎不全, 高血圧症, 血小板減少と診断され入院した. 次第に腎機能が増悪し, 当院へ転院した. 前腕の皮膚硬化やRaynaud症状から強皮症と診断した. 急性腎不全の原因は強皮症腎クリーゼと診断し, ACE阻害薬を中心とした降圧療法を行ったが, 末期腎不全へ至った. 米国へ帰国して, 腎代替療法を導入することを提案したが, 患者は日本で仕事を続けることを強く希望したため, 日本で腹膜透析を導入した. 就労期限の後, 米国へ帰国した. 貴重な症例であり, 腹膜透析の導入から帰国に至るまでの経過を報告する.