A5063110874- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Long-Term Effects of COVID-19
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sinusitis and nasal conditions
- Sepsis Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Pediatric health and respiratory diseases
- COVID-19 and Mental Health
- MicroRNA in disease regulation
- Tryptophan and brain disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammation biomarkers and pathways
- Congenital Diaphragmatic Hernia Studies
- Immune Response and Inflammation
- Global Health Care Issues
- Medical Imaging and Pathology Studies
- Rheumatoid Arthritis Research and Therapies
- Pancreatitis Pathology and Treatment
- COVID-19 Clinical Research Studies
- Occupational exposure and asthma
- Pneumonia and Respiratory Infections
- Air Quality and Health Impacts
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
Al-Azhar University
2021-2024
Al Azhar University
2023
Al-Azhar University
2023
Abstract Background Chronic inflammation plays a crucial role in developing various cardiovascular and metabolic disorders. Obstructive sleep apnea (OSA) is unique condition characterized by the coexistence of disturbances, where chronic may exacerbate disease progression severity. This study investigated how different hematological inflammatory cells mediators can serve as predictive indicators severe OSA. Methods In retrospective cohort study, 150 patients suspected having obstructive...
Abstract Background Severe COVID-19 disease is typically associated with an urgent need for supplemental oxygen therapy that may be successfully delivered through conventional methods or require invasive mechanical ventilation. Early prediction of the ventilation could significantly improve outcomes patients. Plasma levels D-dimer and a number inflammatory markers as well values complete blood counts, all measured in first two days hospital admission patients, were evaluated their...
Cigarette smoking is an important modifiable risk factor in kidney disease progression. Although long-term has been associated with chronic (CKD), its effect on function early stages not clarified.To detect the effects of either active or passive functions.The current study was comparative cross sectional conducted 280 participants, 140 were non‑smokers and smokers (70 70 smokers). The two groups comparable terms all parameters. We investigated possible functions using both serum tests...
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has profound effects on progression and patients' quality life. Emerging evidence suggests an association between alterations in the respiratory microbiome flora species airway inflammation patients with AECOPD. The present study aimed to describe inflammatory cells bacterial distributions tract Egyptian AECOPD.The cross-sectional included 208 Sputum broncho-alveolar lavage samples from studied were submitted microbial...
Background: Rheumatoid arthritis (RA) is a chronic inflammatory condition that impacts not only the musculoskeletal system but also various other systems in body, including cutaneous, ocular, respiratory, cardiovascular, and circulatory systems. MicroRNAs (miRNAs) are class of naturally occurring highly conserved transcripts primarily function regulation gene expression. They accomplish this by facilitating degradation messenger RNA (mRNA) or repressing mRNA translation. miRNAs well-known...
Background: Cigarette smoking is awell-known significant contributor to the development of many illnesses that having an inflammatory component.Smoking has both acute and chronic effects on haematological parameters.Objective: assess impact cigarette complete blood count (CBC) indices some markers erythrocytic sedemitation rate (ESR) C-reactive protein(CRP).Methodology: this case-control study was conducted 30 healthy active smokers passive age sexmatched non-smokers subjects.Data regarding...
<b>Aim: </b>To evaluate the relationships between sputum and bronchoalveolar lavage (BAL) cellular bacterial findings severity of exacerbation chronic obstructive pulmonary disease (ECOPD).<br /> <b>Patients &amp; methods: </b>A cross-section study was conducted on 307 patients with ECOPD. They underwent BAL inflammatory cell count culture.<br <b>Results:</b> Patients severe ECOPD have significantly higher neutrophils percentage (neut.%),...
Objective: To assess the clinical effects of incentive spirometry (IS) and diaphragmatic breathing (DB) in patients with post COVID-19 condition dysfunction as compared standard care alone. Methods: The present longitudinal randomized study included 60 dysfunction. Patients were equally to receive plus IS (G1), DB (G2) or alone (G3) for 8 weeks. primary outcome is improvement evaluated by modified Medical Research Council (mMRC) dyspnoea scale. Results: Comparison between studied groups...
Abstract Background While tuberculosis (TB) remains a significant global health threat, data on mortality in critically ill TB patients and those with drug-resistant (DR-TB) is limited. This study explores hematological profiles of DR-TB, investigating associations in-hospital short-term mortality. Methods A longitudinal 269 confirmed evaluated baseline blood cell counts indices from medical records. We calculated prognosis, followed by analysis to identify predictors using parameters....
Pediatric pneumonia is a common respiratory infection that affects children and thought to be major source of mortality morbidity worldwide, particularly in low- middle-income nations. Toll-like receptor2 (TLR2) an important receptor involved the recognition bacterial pathogens activation immune response. Genetic variability TLR2 may partially explain individual differences susceptibility infections. The purpose this study was investigate possible contribution (rs5743708) variant risk...
Background: Sarcoidosis is a multifactorial disorder of unfamiliar origin characterized by noncaseating granulomas in different body parts .The purpose this investigation was to study the association neuropathy patients with pulmonary sarcoidosis Methods: The included 30 on systemic steroid hypoxia, without hypoxia and not hypoxia.Clinical, neurophysiological, laboratory, radiological histopathological assessment done for them.Results: LANSS pain scale significantly associated neuropathic...
Sarcoidosis is a multisystem granulomatous disease of unknown origin. Ninety percent patients with sarcoidosis have lung involvement. The onset can be acute or non-acute and the severity ranges widely from asymptomatic accidental radiographic findings to severe organ This case control analytic prospective study was conducted at Chest Clinic, Al Zahraa hospital, assess diagnostic value serum soluble interleukin 2 receptor (sIL-2R), cluster differentiation 4 (CD4)/CD8 ratio CD103 in...
Background and Aim: Mental health of non-hospitalized patients those with non-severe infections has attracted lower attention in comparison to other patients. Circulating monocytes are deeply involved all stages COVID-19 infection. The present study aimed investigate the relationship between monocyte-to-lymphocyte ratio (MLR) depressive symptoms Methods: included 312 infection diagnosed on basis a positive reverse-transcriptase polymerase chain reaction (RT-PCR) test nasopharyngeal swabs....
Background: Coexistence of bronchial asthma and allergic nasal polyposis make both disorders more difficult to control with exacerbation eosinophilic inflammation. Aim: assess the coexistence subclinical in patients polyp refractory medical therapy identify those at risk developing asthma. Subjects methods: A case-control study was conducted on 60 healthy subjects. All them were assessed by peripheral eosinophils%, rhinitis score (SFAR), NOSE-score, endoscopic-sinus examination, sinus...
Background: Pneumonia represents a significant public health problem in the whole world, and it is one of leading causes morbidity mortality among children. Disease severity clinical outcome prediction are required pneumonia to manage resources give effective treatment options. Ischemia-modified albumin (IMA) marker recently used oxidant-antioxidant mechanism has been found toin crease many inflammatory conditions. Procalcitonin (PCT) released as part pro-inflammatory response innate immune...
Background: Coexistence of bronchial asthma and allergic nasal polyposis make both disorders more difficult to control with exacerbation eosinophilic inflammation. Aim: assess the coexistence subclinical in patients polyp refractory medical therapy identify those at risk developing asthma. Subjects methods: A case-control study was conducted on 60 healthy subjects. All them were assessed by peripheral eosinophils%, rhinitis score (SFAR), NOSE-score, endoscopic-sinus examination, sinus...