- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Bone Tumor Diagnosis and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Blood Pressure and Hypertension Studies
- Reproductive Biology and Fertility
- Cardiovascular and exercise physiology
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Ovarian function and disorders
- Cardiac Health and Mental Health
- Takotsubo Cardiomyopathy and Associated Phenomena
- Heart Failure Treatment and Management
- Heart rate and cardiovascular health
- Sarcoma Diagnosis and Treatment
- Renin-Angiotensin System Studies
Green Cross (South Korea)
2025
Sungkyunkwan University
2014-2024
Samsung (South Korea)
2001-2024
Chonnam National University Hospital
2023-2024
Samsung Medical Center
2013-2023
University of Cincinnati
2023
University of Cincinnati Medical Center
2023
Pohang SeMyeong Christianity Hospital
2016-2018
University of Alberta
2016-2017
Tianjin First Center Hospital
2012-2013
<h3>Background</h3> Whether final kissing ballooning (FKB) is mandatory in the 1-stent technique uncertain. <h3>Objective</h3> To evaluate effect of FKB on long-term clinical outcomes coronary bifurcation lesions treated with technique. <h3>Methods</h3> Consecutive patients undergoing percutaneous intervention using drug-eluting stents for non-left main were enrolled from 16 centres Korea between January 2004 and June 2006. In major adverse cardiac events (MACE; death, myocardial infarction...
Although carina shift and plaque are suggested as mechanisms of side branch ostial (SBo) compromise after main vessel (MV) stenting in bifurcation lesions, there few direct evidence. Our purpose was to confirm the mechanism SBo MV stent implantation.Intravascular ultrasound images both SB before procedure immediately were evaluated 44 lesions. Three 5 mm segments interest volumetrically analyzed: proximal MV, distal SBo. defined a lumen volume decrease, increase segment stenting. The...
Background As an initial treatment strategy, percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) did not show midterm survival benefits compared with optimal medical therapy (OMT). We sought to evaluate the benefit of PCI OMT in patients CTO over extended long-term follow-up. Methods and Results Between March 2003 February 2012, 2024 were enrolled a single-center registry followed ≈10 years. excluded who underwent artery bypass graft (n=477) classified into CTO-PCI...
Data on the association between glycemic control after percutaneous coronary intervention and clinical outcomes are limited controversial in diabetic patients.We studied 980 patients with type 2 diabetes mellitus undergoing using drug-eluting stents. Based 2-year glycosylated hemoglobin A (HbA1c) levels, we divided into groups of HbA1c<7.0 (n=489) HbA1c≥7.0 (n=491). Propensity score-matched analysis was performed 322 pairs. The primary outcome major adverse cardiac cerebrovascular events...
Background— The use of dual-antiplatelet therapy (DAPT) exceeding 12 months may increase a bleeding risk despite lower ischemic events. There is no study to compare clinical outcomes in patients treated with single-antiplatelet drug after DAPT the era drug-eluting stents (DES). We sought investigate efficacy and safety clopidogrel versus aspirin monotherapy 12-month DES implantation using an institutional registry. Methods Results— This observational was conducted on consecutive receiving...
Abstract Background: We sought to compare long‐term outcomes for multivessel revascularization (MVR) vs single‐vessel (SVR) with drug‐eluting stents (DES) in patients non–ST‐segment elevation acute coronary syndrome (NSTE‐ACS) and artery disease (MVD). Hypothesis: In DES era, MVR would improve clinical NSTE‐ACS. Methods: studied 179 undergoing 187 SVR NSTE‐ACS MVD. Major adverse cardiac events (MACE) were defined as death, myocardial infarction, or any revascularization. Results: During...
Background/Objectives: Acetaminophen (APAP) is a widely used analgesic and antipyretic, but overdose can lead to APAP-induced liver injury (AILI), major cause of acute failure. While N-acetylcysteine (NAC) the current standard care, its efficacy significantly reduced when administered after peak time injury, highlighting need for alternative therapeutic strategies. Human placenta hydrolysate (HPH) has shown potential as agent various diseases due rich content bioactive compounds. This study...
A case of catecholamine cardiomyopathy associated with paraganglioma, which was rescued by percutaneous cardiopulmonary support system (PCPS), is presented. Unlike typical apical ballooning, transthoracic echocardiography and left ventriculography revealed severe ventricular (LV) dysfunction an abnormal contractile pattern, consisting akinesis the basal midventricular segments hyperkinesis segments. Because intractable cardiogenic shock, despite conventional treatment, PCPS performed. The...
Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, use of non-compliant may reduce side branch complications and optimise stent deployment. We sought to investigate impact on long-term clinical outcomes patients undergoing coronary bifurcation intervention.A total 2,897 treated with drug-eluting stents for lesions were enrolled. used in 752 (26%). During median three-year follow-up, major adverse cardiac events (MACE: death,...
Background: The optimal duration of dual antiplatelet therapy remains controversial. Methods and Results: Between December 2006 March 2008, 823 patients were enrolled in a prospective multicenter registry for 3-month (aspirin 100-200mg+clopidogrel 75mg daily) followed by aspirin mono-therapy after zotarolimus-eluting stents (ZES). Major exclusion criteria were: cardiogenic shock, stent thrombosis (ST)-segment elevation myocardial infarction (MI) within 48h, previous drug-eluting...
The aim of this study was to compare the long-term clinical outcomes patients with chronic total occlusion (CTO) treated percutaneous coronary intervention (PCI) versus medical therapy (MT) according presence diabetes mellitus.A 845 without and 702 were included from Samsung Medical Center CTO registry. inverse probability treatment weighting (IPTW) method used adjust for confounding factors. primary outcome cardiac death. Median follow-up duration 46 (interquartile range: 23-71) months....
Abstract Background : N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) is increased in patients with hypertrophic cardiomyopathy (HCM); however, the determinants of NT‐proBNP level have not been clarified HCM. Hypothesis This study was performed to determine relationship between levels and various echocardiographic variables HCM normal left ventricular ejection fraction (LVEF). Methods We assessed plasma 36 (19 men, 58 ± 14 years) an LVEF ≥ 55%. Echocardiographic measured were LV wall...
Migraine is a neurovascular disorder that affects approximately 12% of the global population. While its exact causes are still being studied, researchers believe nociceptors in trigeminal ganglia play key role pain signals migraine. These innervate intracranial meninges and convey from to thalamus. Targeting these considered promising due their accessibility distinct molecular profile, which includes expression several transient receptor potential (TRP) channels. channels have been linked...
The N-terminal fragment of pro Brain Natriuretic Peptide (NT-pro BNP) is a neuro-hormone synthesized in the cardiac ventricles response to increased wall tension. purpose this study was assess correlation between NT-pro BNP levels and New York Heart Association function class (NYHA Fc) dyspnea echocardiographic findings for patients who visited our cardiology departments.From October, 2002 April, 2003, serum were measured 348 Samsung Medical Center Jong Koo Lee Clinic.The with progression...