A5101517809- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Coronary Artery Anomalies
- Mitochondrial Function and Pathology
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Long-Term Effects of COVID-19
- Atrial Fibrillation Management and Outcomes
- Cardiac tumors and thrombi
- Potato Plant Research
- Cardiac pacing and defibrillation studies
- Pluripotent Stem Cells Research
- Cardiovascular Issues in Pregnancy
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Cerebrovascular and Carotid Artery Diseases
- Blood Pressure and Hypertension Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Apelin-related biomedical research
Inje University Ilsan Paik Hospital
2020-2025
Seoul Institute
2025
Inje University
2011-2024
Sungkyunkwan University
2009-2024
Green Cross Laboratories (South Korea)
2024
University of Utah
2024
Cedars-Sinai Medical Center
2024
St. Vincent's Hospital
2024
GTx (United States)
2024
Inje University Seoul Paik Hospital
2017-2019
A recent randomised trial demonstrated fractional flow reserve (FFR) guidance for percutaneous coronary intervention (PCI) was non-inferior to intravascular ultrasound (IVUS) regarding clinical outcomes, with a lower frequency of PCI. We sought evaluate the prognosis FFR versus IVUS PCI intermediate artery stenosis and low lesion complexity in diabetic non-diabetic patients. This study is prespecified post hoc analysis from FLAVOUR trial. The primary outcome major adverse cardiac events...
Echinochrome A (EchA) is a natural bioproduct extracted from sea urchins, and an active component of the clinical drug, Histochrome®. EchA has antioxidant, anti-inflammatory, antimicrobial effects. However, its effects on diabetic nephropathy (DN) remain poorly understood. In present study, seven-week-old obese db/db mice were injected with Histochrome (0.3 mL/kg/day; equivalent 3 mg/kg/day) intraperitoneally for 12 weeks, while control wild-type (WT) received equal amount sterile 0.9%...
Coronary artery disease (CAD) is a major determinant of long-term prognosis in patients with peripheral (PAD). We investigated the predictors CAD lower extremity PAD.A total 107 PAD who underwent and simultaneous coronary angiography were reviewed. was defined as (≥ 50%) stenosis associated claudication or critical limb ischemia. divided into proximal distal lesions. angiographically significant arteries.The prevalence 62% (67/107), this 62%, only 13% (9/67) had angina 72% (48/67)...
Coronary vasospasm is an important pathogenesis of acute coronary syndrome (ACS). However, the clinical features and prognosis vasospastic angina (VA) patients presenting with ACS (VAACS) are still unclear. We aimed to evaluate characteristics long-term outcomes VAACS without significant artery stenosis.
ABSTRACT It is important to efficiently recover (oo)cysts in water during the established detection process, as Cryptosporidium and Giardia are known cause waterborne outbreaks. We investigated recovery of these based on pH HCl NaOH used immunomagnetic separation (IMS) step. Additionally, we evaluated efficiency heat dissociation a potential alternative acid IMS. The results showed that rates decreased final deviated from neutral. highest rates, exceeding 60%, were observed when 0.1 N 1 fell...
Background: Whether prolonged dual antiplatelet therapy (DAPT) improves clinical outcomes after percutaneous coronary intervention for bifurcation lesion is uncertain. Methods and Results: We evaluated 2082 patients who were treated with drug-eluting stent lesions event free (no death, myocardial infarction [MI], cerebrovascular accident, thrombosis, or any revascularization) at 12 months the index procedure. Patients divided into 2 groups: DAPT ≥12-month group (n=1776) <12-month (n=306)....
Nanoscaled surface patterning is an emerging potential method of directing the fate stem cells. We adopted nanoscaled pillar gradient patterned cell culture plates with three diameter gradients [280-360 (GP 280/360), 200-280 200/280), and 120-200 nm 120/200)] investigated their fate-modifying effect on multipotent fetal liver kinase 1-positive mesodermal precursor cells (Flk1+ MPCs) derived from embryonic observed increased proliferation colony formation Flk1+ MPCs nanopattern plates....
Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, the active component of clinical drug histochrome. We investigated potential use Ech for inducing cardiomyocyte differentiation mouse embryonic stem cells (mESCs). also assessed effects on mitochondrial mass, inner membrane (Δψm), reactive oxygen species generation, levels Ca2+. To identify direct target A, we performed in vitro kinase activity...
There are multiple lines of evidence that persimmon extract and its constituents have potent antitumor activity against human cancer cells. However, the molecular mechanisms 24-hydroxyursolic acid, a triterpenoid found in persimmon, on activities not yet understood. Here, we demonstrate acid inhibited cell proliferation, strongly activated AMP-activated protein kinase (AMPK) mediated critical anticancer effects by inhibition cyclooxygenase (COX-2) expression HT-29 In addition, induced...
Primary cardiac lymphomas (PCL) are extremely rare. Clinical manifestations may be variable and attributed to location. Here, we report on a case of PCL presenting with atrioventricular (AV) block. A 55 year-old male had experienced chest discomfort unexplained dyspnea night sweating. His initial electrocardiogram (ECG) revealed first degree AV Along worsening dyspnea, his ECG changed show second block (Mobitz type I). Computed tomography (CT) scan showed mass (about 7 cm) biopsy was...