A5002207908- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Epigenetics and DNA Methylation
- Maternal and fetal healthcare
- Diabetes Management and Research
- Prenatal Screening and Diagnostics
- Simulation-Based Education in Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nursing Roles and Practices
- Preterm Birth and Chorioamnionitis
- Health, Environment, Cognitive Aging
- Telemedicine and Telehealth Implementation
- Mobile Health and mHealth Applications
- Blood Pressure and Hypertension Studies
- Pluripotent Stem Cells Research
- Adipose Tissue and Metabolism
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Perinatal Health Interventions
- Pregnancy and Medication Impact
- Hospital Admissions and Outcomes
- Autopsy Techniques and Outcomes
- Electronic Health Records Systems
- Cancer Risks and Factors
- Healthcare Systems and Technology
New York University
2018-2025
Long Island University
2020-2025
NYU Langone Health
2020-2024
Island Hospital
2021-2023
Winthrop-University Hospital
2016-2021
Stony Brook University Hospital
2019-2021
Pusan National University
2020
Inje University
2018
Albert Einstein College of Medicine
2007-2016
Montefiore Medical Center
2007-2015
In Brief OBJECTIVE: To estimate whether shoulder dystocia documentation could be improved with a simulation-based educational experience. METHODS: Obstetricians at our institution (n=71) participated in an unanticipated simulated followed by debriefing session. A second simulation was completed later date. Delivery notes were required component of each simulation. Notes evaluated using standardized checklist for 16 key components. One point awarded element present. Wilcoxon signed rank tests...
Cells in maternal and fetal immune systems may communicate, leading to tolerance during pregnancy; however, this hypothesis remains controversial. Here, we profiled single cell transcriptional signatures placental layers comprising the maternal–fetal interface deep placenta, then searched for genes associated with preeclampsia. To investigate underlying principle of failure tolerance, started by clarifying systemic framework, models interaction frequency (IIF) specific triggers (i.e.,...
Social determinants of health (SDOH) may impact the incidence Respiratory Syncytial Virus (RSV) infection and uptake vaccinations in pregnancy. The objective this study is to identify contributors disparities RSV vaccination This a retrospective cohort patients delivering at term within three hospitals during February March 2024, comparing pregnant identified as receiving vs not vaccinations. period gestational age were chosen include who would have qualified for administration. Vaccination...
The rapid evolution of large-language models such as ChatGPT, Claude, and Gemini is reshaping the methodological landscape obstetrics gynecology (OBGYN) research. This narrative review provides a comprehensive account generative AI capabilities, key use-cases, recommended safeguards for investigators. First, expedites hypothesis generation, enabling researchers to interrogate vast corpora surface plausible, overlooked questions. Second, it streamlines systematic reviews by composing...
Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, the active component of clinical drug histochrome. We investigated potential use Ech for inducing cardiomyocyte differentiation mouse embryonic stem cells (mESCs). also assessed effects on mitochondrial mass, inner membrane (Δψm), reactive oxygen species generation, levels Ca2+. To identify direct target A, we performed in vitro kinase activity...
Adverse environmental exposures of mothers during fetal period predispose offspring to a range age-related diseases earlier in life. Here, we set determine whether deregulated epigenetic pattern is similar young animals whose mothers' nutrition was modulated growth that acquired normal aging animals. Using rodent model maternal undernutrition (UN) or overnutrition (ON), examined cytosine methylation profiles liver from female and compared them age-matched controls aged (20-month-old)...
Preeclampsia, traditionally characterized by high blood pressure and proteinuria, is a common pregnancy complication, which affects 2–8 % of all pregnancies. Although children born to women with preeclampsia have higher risk hypertension in later life, the mechanism this increased unknown. DNA methylation an epigenetic modification that has been studied as mediator cellular memory adverse exposures utero. Since each cell type body unique profile, subtype composition major confounding factor...
Accurate prediction of malignancies is important in choosing therapeutic strategies. Although there are many genetic and cytogenetic prognostic factors for acute myeloid leukemia (AML), prognosis difficult to predict because the heterogeneity AML. Prognostic factors, including messenger RNA (mRNA) expression, have been determined other malignancies, but not A total 402 patients from The Cancer Genome Atlas, GSE12417 (GPL96, 97), (GPL570) were included this study. In Kaplan-Meier curve...
Hyperglycemia and other adverse exposures early in life that reprogram stem cells may lead to long-lasting phenotypic influences over the lifetime of an individual. oxidative stress cause DNA damage when they exceed protective capabilities cell, turn affecting cellular function. response hyperglycemia was studied human umbilical cord mesenchymal (hUC-MSCs) from large-for-gestational-age (LGA) infants mothers with gestational diabetes mellitus (LGA-GDM) control subjects. We tested these...
Objective Due to poor adherence for glucose testing at 6- 12-week postpartum among women with gestational diabetes, we sought determine whether a 2-hour tolerance test (GTT) during hospitalization is predictive of testing. Study Design An institutional review board–approved prospective cohort study was performed over 3 years. Patients underwent an inpatient fasting 75-g, GTT on either days 2 through 4 and instructed follow up in 12-weeks Sensitivity, specificity, positive value (PPV),...
The transformation of health care during COVID-19, with the rapid expansion telemedicine visits, presents new challenges to chronic and preventive providers. Clinical decision support (CDS) is critically important providers, CDS malfunction common times change. It essential regularly reassess an organization's ambulatory program maintain quality. This especially true after immense change, like COVID-19 expansion.