A5080745185- Multiple Sclerosis Research Studies
- Traumatic Brain Injury Research
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Salivary Gland Disorders and Functions
- Cardiac Arrest and Resuscitation
- AI in cancer detection
- Mental Health Treatment and Access
- Family Support in Illness
- Medical Research and Treatments
- Global Health Workforce Issues
- Traumatic Ocular and Foreign Body Injuries
- Dementia and Cognitive Impairment Research
- Healthcare Systems and Public Health
- Neurobiology of Language and Bilingualism
- RNA regulation and disease
- Neonatal and fetal brain pathology
- Restraint-Related Deaths
- Neurological Disease Mechanisms and Treatments
- Effects of Vibration on Health
- Cardiovascular and Diving-Related Complications
- Pediatric health and respiratory diseases
- Cognitive Functions and Memory
Rutgers, The State University of New Jersey
2022-2023
Rutgers New Jersey Medical School
2022-2023
Kessler Foundation
2021-2023
Pennsylvania State University
2014-2021
Brown University
2020-2021
University of California, Los Angeles
2011-2014
Universidad de La Sabana
2014
In the cognitive and clinical neurosciences, past decade has been marked by dramatic growth in a literature examining brain "connectivity" using noninvasive methods. We offer critical review of blood oxygen level dependent functional MRI (BOLD fMRI) neural connectivity changes neurological disorders with focus on injury dementia. The goal is to demonstrate that there are identifiable shifts local large-scale network can be predicted degree pathology. anticipate most common response insult...
There remains much unknown about how large-scale neural networks accommodate neurological disruption, such as moderate and severe traumatic brain injury (TBI). A primary goal in this study was to examine the alterations network topology occurring during first year of recovery following TBI. To do so we examined 21 individuals with TBI at 3 6 months after resolution posttraumatic amnesia 15 age- education-matched healthy adults using functional MRI graph theoretical analyses. were two central...
BackgroundThe Symbol Digit Modalities Tests (SDMT) is the most sensitive measure to multiple sclerosis (MS)-related cognitive dysfunction. However, existing normative data has been under scrutiny. Specifically, they are outdated, do not take into account gender, and poorly stratified by education. More importantly, there exists no oral only version norms, which typical administration among individuals with MS.ObjectiveThe present investigation aimed develop updated of SDMT in age, education...
BackgroundDepression is three to four times more prevalent in patients with neurological and inflammatory disorders than the general population. For example, multiple sclerosis, 12-month prevalence of major depressive disorder around 25% it associated a lower quality life, faster disease progression, higher morbidity mortality. Despite its clinical relevance, there are few treatment options for depression sclerosis confirmatory trials scarce. We aimed evaluate safety efficacy...
The use of normative data is a hallmark the neuropsychological assessment process. Within context sports-related concussion, utilizing especially essential when individualized baseline are unavailable for comparison. primary purpose this study was to establish comprehensive test battery used in concussion. A secondary aim provide pertinent demographic variables relevant college athletes, including sex, previous head injuries (PHI), and history attention deficit hyperactivity disorder...
Objective: Based on evidence linking creativity and bipolar disorder, a model has been proposed whereby factors influencing liability to disorder confer certain traits with positive effects reproductive fitness. The authors tested this by examining key known be associated evolutionary fitness, namely, temperament neurocognition, in individuals carrying for disorder. Schizophrenia probands their co-twins were included as psychiatric controls. Method: Twin pairs discordant schizophrenia...
The oral Symbol Digit Modalities Test (SDMT) has become the standard for brief screening of cognitive impairment in persons with multiple sclerosis (PwMS). It been shown to be sensitive sensory-motor factors involving rudimentary motor speed and visual acuity, as well (MS) affective-fatigue including depression, fatigue, anxiety. present study was designed provide a greater understanding these noncognitive that might contribute SDMT by examining all variables same sample. We examined 50 PwMS...
Abstract Objective The purpose of this study was to explore racial/ethnic differences in neurobehavioral symptom reporting and validity testing among military veterans with a history traumatic brain injury (TBI). Method Participants observational cross-sectional (N = 9,646) were post-deployed Iraq-/Afghanistan-era enrolled the VA’s Million Veteran Program clinician-confirmed TBI on Comprehensive Evaluation (CTBIE). Racial/ethnic groups included White, Black, Hispanic, Asian, Multiracial,...
Abstract Because cognitive fatigue (CF) is common and debilitating following brain injury or disease we investigated the relationships among CF, behavioral performance, cerebral activation within across populations by combining data from two cross-sectional studies. Individuals with multiple sclerosis (MS) were included to model CF resulting neurological disease; individuals who had sustained a traumatic (TBI) insult; both groups compared control group (Controls). was induced while...
Multiple Sclerosis (MS) affects 2.8 million persons worldwide. One of the most persistent, pervasive, and debilitating symptoms MS is cognitive fatigue. While this has been known for over a century, fatigue difficult to study because patients' subjective (self-reported) consistently failed correlate with more objective measures, such as reaction time (RT) accuracy. Here, we investigated whether nuanced metrics performance, specifically Signal Detection Theory (SDT), would show relationship...
Fatigue, including cognitive fatigue, is one of the most debilitating symptoms reported by persons with multiple sclerosis (pwMS). Cognitive fatigue has been associated disruptions in striato-thalamo-cortical and frontal networks, but what remains unknown how rate at which pwMS become fatigued over time relates to microstructural properties within brain. The current study aims fill this gap knowledge investigating white matter basal ganglia microstructure a sample 62 relapsing-remitting MS....
Abstract Objective: Accelerated brain aging (ABA) has been identified in neurological/psychological populations and associated with poorer outcomes. Though studies multiple sclerosis (MS) are limited, ABA MS linked to disease progression disability. What remains unknown is how related cognitive functioning MS. We hypothesized that greater levels of would be performance on tests higher disability persons (pwMS). Method: Each participant’s (N&#3f40; ages 35+) “brain age” was calculated...
En el presente documento se analiza régimen de inversiones internacionales vigente en Colombia, dictado por Gobierno Nacional cumplimiento lo dispuesto la Ley Marco Cambios Internacionales (Ley 9 1991). Asimismo, abordan las dos grandes categorías internacionales: inversión extranjera y Colombiana exterior. Mediante descripción explicación los presupuestos procedimientos este pretende aclarar requisitos básicos para realización internacionales.
Becoming culturally competent healthcare providers depends on the ability of practitioners to acquire knowledge, awareness, and skills related other cultures. In building these areas competence, it is essential consider geopolitical factors that may influence health health-seeking behaviors, particularly when working with immigrant populations. When care sought, they are likely experience significant barriers effective care, including lack who speak their language failure integrate cultural...
<title>Abstract</title> Because cognitive fatigue (CF) is common and debilitating following brain injury or disease we investigated the relationships among CF, behavioral performance, cerebral activation within across populations by combining data from two cross-sectional studies. Individuals with multiple sclerosis (MS) were included to model CF resulting neurological disease; individuals who had sustained a traumatic (TBI) insult; both groups compared control group (Controls). was induced...
Racially/ethnically diverse persons with multiple sclerosis (pwMS) have worse outcomes than their white counterparts. Barriers to healthcare access may contribute these disparities, though much remains unknown. The current pilot study investigates the impact of barriers on cognition and accelerated brain aging in pwMS. We hypothesize that greater will be associated poorer cognitive performance increased aging.Eighteen middle-aged pwMS (40-60 years) were included. was evaluated using total...
Coping style has been identified as a potential strategy to lessen the impact of negative symptoms in persons with MS (pwMS). Prior work demonstrates that individuals executive dysfunction are less likely use effective coping strategies. Much remains unknown about relationship between functioning (EF) and style, however, especially diverse pwMS. The current pilot study aims examine this further.Eighteen middle aged pwMS (10 = Latino/a, 6 African American, 1 Asian, Biracial) underwent...
Objective: Multiple sclerosis (MS) has historically been considered a syndrome that primarily affects White persons of northern European ancestry. This strongly disproven in recent decades with prevalence/incidence studies showing MS impacts individuals from diverse backgrounds. The few available investigating clinical characteristics across groups have shown Hispanic/Latinx/e (Latinx) and non-Hispanic Black/African American (NHB) (pwMS) more severe disease trajectories compared to Whites...
Introduction: A number of recent well publicized deaths from police chokeholds have focused attention on the use and safety by law enforcement officers (LEO). LEO are depicted as a safe non-lethal restraint technique. Use is purported to be in middle range force options when compared other tools available. often likened judo which long history not directly contributed death judoka since sport Judo was founded Japan 1882. Some posited that employed especially likely young adults, they less...