A5020391993- Dementia and Cognitive Impairment Research
- Neurological disorders and treatments
- Neurobiology of Language and Bilingualism
- Traumatic Brain Injury Research
- Parkinson's Disease Mechanisms and Treatments
- Cognitive Functions and Memory
- Epilepsy research and treatment
- Educational and Psychological Assessments
- Amyotrophic Lateral Sclerosis Research
- Psychosomatic Disorders and Their Treatments
- Language Development and Disorders
- Obsessive-Compulsive Spectrum Disorders
- Transcranial Magnetic Stimulation Studies
- Autism Spectrum Disorder Research
- Neurogenetic and Muscular Disorders Research
- Health Systems, Economic Evaluations, Quality of Life
- Counseling Practices and Supervision
- Neuroscience, Education and Cognitive Function
- Botulinum Toxin and Related Neurological Disorders
- EEG and Brain-Computer Interfaces
- Health and Well-being Studies
- Retinal Imaging and Analysis
- Schizophrenia research and treatment
- Alzheimer's disease research and treatments
- Cardiac Arrest and Resuscitation
Baylor College of Medicine
2012-2023
New York Proton Center
2020
American Headache Society
2020
Texas Medical Center
2020
Amyotrophic Lateral Sclerosis Association
2012
The success of deep brain stimulation (DBS) for treating Parkinson's disease has led to its application several other disorders, including treatment-resistant depression. Results with DBS depression have been heterogeneous, inconsistencies largely driven by incomplete understanding the networks regulating mood, especially on an individual basis. We report results from first subject treated using approach that incorporates intracranial recordings personalize network behavior and response...
Up to half of patients with ALS develop cognitive impairment during the course illness. Despite this, there is no simple tool for screening in clinical setting. This study examines sensitivity, specificity and accuracy Cognitive Behavioral Screen (ALS-CBS™). We administered measure 112 patients, including 31 who also underwent comprehensive neuropsychological testing. results were validated by determining against full battery. Optimal cut-off scores predicting correct diagnosis determined,...
Cognitive impairment secondary to frontal lobe atrophy exists in 40-60% of Amyotrophic Lateral Sclerosis (ALS) cases. We aimed determine the prevalence frontal-lobe mediated behavioral and ascertain its relationship cognitive impairment.Two-hundred twenty five patients diagnosed with sporadic ALS were evaluated for dysfunction using Frontal Systems Behavior Scale (FrSBe), a validated measure used examine behaviors, specifically apathy, executive disinhibition; total behavior score is also...
Better tools for assessing cognitive impairment in the early stages of Alzheimer's disease (AD) are required to enable diagnosis before substantial neurodegeneration has taken place and allow detection subtle changes progression disease. The National Institute on Aging Association convened a meeting discuss state art methods assessment, including computerized batteries, as well new approaches pipeline. Speakers described research using novel tests object recognition, spatial navigation,...
Several metabolic derangements associated with diabetes mellitus type 2 (DM) have been a better outcome in amyotrophic lateral sclerosis (ALS), including hyperlipidemia and obesity. Here, we tested the hypothesis that DM would positive effect on motor cognitive findings of ALS.We compared data from ALS patients pre-morbid (ALS-DM; n = 175) versus without (ALS; 2196) regard to age onset, rate progression, survival, neuropsychological test performance.The onset was later for women, Caucasians...
Background and purpose: Subthalamic nucleus deep brain stimulation (STN‐DBS) has been shown to have beneficial effects on the motor features of Parkinson’s disease (PD), but its impact non‐motor symptoms, most notably mood, not fully explored. Methods: In first study independently compare emotional‐cognitive somatic/physiological symptoms depression, we examined mood differences in 17 bilateral STN‐DBS 22 matched non‐surgical PD patients at baseline 6 months. Results: The group reported...
Objective: To evaluate the role of neurocognitive impairment on retention in care across lifespan antiretroviral-naïve persons newly diagnosed with HIV. Design: A prospective observational study 138 antiretroviral-naive HIV-positive participants who presented to an urban clinic between August 2010 and April 2013. Methods: All underwent a baseline evaluation that included neuromedical examination brief neuropsychological test battery. Retention was operationalized as attending at least two...
Neuropsychological assessments with monolingual Spanish and bilingual Spanish/English-speaking adults present unique challenges. Barriers include, but are not limited to, the paucity of test norms, uncertainty about equivalence translated neuropsychological tests, proficiency in provision culturally competent services. Similar issues generalize to telephone- video-based administration tests or teleneuropsychology (TeleNP) Hispanics/Latinos (as), few studies have examined its feasibility...
In this position article, we highlight the importance of considering cultural and linguistic variables that influence neuropsychological test performance possible moderating impact on our understanding brain/behavior relationships. Increasingly, neuropsychologists are realizing language differences between countries, regions, ethnic groups outcomes, as scores may not have same interpretative meaning across cultures. Furthermore, attempts to apply norms diverse populations without accounting...
To quantify the areas of burden experienced by patients requiring repeated intravitreal injections (IVI) in management exudative retinal diseases.The validated Questionnaire to Assess Life Impact Treatment Intravitreal Injections survey was administered at four retina clinical practices across US states. The primary outcome measure Burden Score (TBS), a single score assessing overall burden.Of 1416 (n=657 age-related macular degeneration; n=360 diabetic oedema/diabetic retinopathy; n=221...
Primary objectives: To examine the clinical utility of Test Memory Malingering (TOMM) with US Spanish speaking patients diagnosed traumatic brain injury (TBI).Research design: The demographic characteristics and neuropsychological functioning TBI valid vs suboptimal performance were compared.Methods procedures: Demographic data retrospectively collected from charts who underwent neurocognitive evaluations for clinical, med-legal workmen's compensation purposes. Slick et al. criteria...
A brain health equity neuropsychology research framework (NRF) is crucial to the anti-racist movement in cognitive assessments. Universalist interpretation of neuropsychological tools contributes systemic disparities, and there a need for clear conceptual disentangling direct indirect impact social determinants (SDH) on brain-behavior relationships performance. The aim this paper present NRF anchored principles that inclusive, can be implemented across racially ethnically diverse...
The training competency of individual and cultural diversity is an advanced, fundamental to health service psychology since 2015. However, there minimal instruction on how integrate it into curricula in neuropsychology, especially at the postdoctoral fellowship level. Our objective was operationalize standard provide a tangible application for educational programs develop competency-based model Latinx/a/o-Hispanic (L/H) neuropsychology across lifespan.The knowledge-based applied-based...
Amyotrophic lateral sclerosis (ALS) has been associated with changes in frontal and temporal lobe-mediated cognitive behavioral functions. Verbal fluency, a sensitive measure to these changes, was utilized investigate phonemic semantic abilities 49 ALS patients 25 healthy controls (HCs). A subset of the classified as ALS-intact, mild impairments (ALS-mild), fronto-temporal dementia (ALS-FTD) based on comprehensive neuropsychological evaluation. Clustering switching, underlying component...
Psychogenic movement disorders (PMDs) often result in disability and diminished quality of life, yet medical therapies are presently limited largely ineffective. On the basis previous reports that transcutaneous electrical nerve stimulation (TENS) is helpful for certain patients with organic disorders, authors studied effects TENS 19 PMDs, utilizing Movement Disorder Rating Scale (PMDRS) as well patient-rated assessments PMD magnitude, persistence, disability. The PMDRS Severity score...
Background and purpose Despite common occurrences of verbal fluency declines following bilateral subthalamic nucleus deep brain stimulation ( STN ‐ DBS ) for the treatment Parkinson's disease PD ), alternating measures using cued uncued paradigms have not been evaluated. Methods Twenty‐three patients were compared with 20 non‐surgical on a comprehensive neuropsychological assessment, including intradimensional (phonemic/phonemic semantic/semantic) extradimensional (phonemic/semantic) at...
The Rey 15-Item Memory Test (Rey-15) is a standard instrument frequently employed to assess suspect effort/motivation in English-speaking populations. objective of the current study was examine influence socio-demographic variables on this measure and provide normative data for use with Spanish speakers. performance 130 primarily Spanish-speaking, cognitively intact, older adults (ages 50-69) six Rey-15 scoring systems embedded measures suboptimal examined. Approximately 8% sample scored...
Several studies have demonstrated impaired cognition in amyotrophic lateral sclerosis (ALS) patients, but it has been difficult to identify risk factors for this impairment. An association between cognitive changes and bulbar site of onset or dysarthria suggested, the findings are variable. We tested both associations a large cohort ALS patients. At time diagnosis sporadic ALS, all patients (n=355) prospective study underwent comprehensive neuropsychological testing. In addition, subset 175...
Objectives To describe the phenomenology and prevalence of leg stereotypy syndrome (LSS), characterised chiefly by repetitive, rhythmical, stereotypic movement, especially when sitting. Methods We sought to characterise LSS in two groups subjects: (1) general population (GP) group, defined as individuals accompanying patients during their visits Baylor College Medicine Parkinson’s Disease Center Movement Disorders Clinic who are not genetically related patients; (2) movement disorders (MD)...