- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Moyamoya disease diagnosis and treatment
- Lower Extremity Biomechanics and Pathologies
- Venous Thromboembolism Diagnosis and Management
- Diabetic Foot Ulcer Assessment and Management
- Foot and Ankle Surgery
- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- COVID-19 Pandemic Impacts
- COVID-19 and Mental Health
- Infection Control and Ventilation
- Intracranial Aneurysms: Treatment and Complications
- Neurological Complications and Syndromes
- Advanced MRI Techniques and Applications
- Drilling and Well Engineering
- Prosthetics and Rehabilitation Robotics
- S100 Proteins and Annexins
- Coronary Artery Anomalies
- Apelin-related biomedical research
- Muscle activation and electromyography studies
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Sun Yat-sen University
2007-2025
The Seventh Affiliated Hospital of Sun Yat-sen University
2017-2025
Ministry of Agriculture and Rural Affairs
2022
Guangzhou Medical University
2011-2018
Second Affiliated Hospital of Guangzhou Medical University
2011-2018
University of Virginia
2013-2017
Guangdong Provincial People's Hospital
2016-2017
University of Virginia Hospital
2016
Columbia University
2014
Stanford University
2014
Background and Purpose— Although arteriopathies are the most common cause of childhood arterial ischemic stroke, strongest predictor recurrent they difficult to diagnose. We studied role clinical data follow-up imaging in diagnosing cerebral cervical arteriopathy children with stroke. Methods— Vascular effects infection pediatric an international prospective study, enrolled 355 cases stroke (age, 29 days 18 years) at 39 centers. A neuroradiologist neurologist independently reviewed vascular...
Background and Purpose- Although perfusion abnormality is an increasingly important therapeutic target, the natural history of tissue at risk without reperfusion treatment understudied. Our objective was to determine how time affects penumbral salvage infarct growth in untreated acute ischemic stroke patients whether collateral status this relationship. Methods- We used a prospectively collected, multicenter registry assess who were not treated with intravenous thrombolysis or endovascular...
<h3>BACKGROUND AND PURPOSE:</h3> Childhood arteriopathies are rare but heterogenous, and difficult to diagnose classify, especially by nonexperts. We quantified clinical imaging characteristics associated with childhood arteriopathy subtypes facilitate their diagnosis classification in research settings. <h3>MATERIALS METHODS:</h3> The Vascular Effects of Infection Pediatric Stroke (VIPS) study prospectively enrolled 355 children arterial ischemic stroke (2010–2014). A central team experts...
Maintaining compliance with personal preventive measures is important to achieve a balance of COVID-19 pandemic control and work resumption.
Background and Purpose— To investigate the effect of chronic hyperglycemia on cerebral microvascular remodeling using perfusion computed tomography. Methods— We retrospectively identified 26 patients from our registry 2453 who underwent a tomographic study had their hemoglobin A 1c (HbA ) measured. These were divided into 2 groups: those with HbA >6.5% (n=15) ≤6.5% (n=11). Perfusion studies processed delay-corrected, deconvolution-based software. values compared between patient groups,...
Secondary degeneration in areas beyond ischemic foci can inhibit poststroke recovery. The cysteine protease Cathepsin B (CathB) regulates cell death and intracellular protein catabolism. To investigate the roles of CathB development secondary ventroposterior nucleus (VPN) ipsilateral thalamus after focal cerebral infarction, infarct volumes, immunohistochemistry immunofluorescence, Western blotting analyses were conducted a distal middle artery occlusion (dMCAO) stroke model adult rats. We...
Stroke is the leading cause of adult disability in world. In general, recovery from stroke incomplete. Accumulating evidences have shown that focal cerebral infarction leads to dynamic trans-neuronal degeneration non-ischemic remote brain regions, with disruption connections synapsed neurons sustaining ischemic insults. Previously, we had reported ipsilateral striatum, thalamus degenerated succession after permanent distal branch middle artery occlusion (dMCAO) Sprague-Dawley (SD) rats and...
Accurate gait event detection is necessary for control strategies of rehabilitation robots. However, due to personal diversity between individuals, it a challenge robots detect at various stride frequencies. This paper proposes novel method robot using single inertial sensor mounted on the thigh. A self-adaptive threshold detecting heel strike obtained in real time via linear regression model. Observable thresholds toe off are constant Experiments conducted based 20 healthy subjects and six...
We aim to test how well modern nonhabitual barefoot people can adapt and Minimalist Bare Foot Technology (MBFT) shoes, in regard gait symmetry. 28 healthy university students (22 females/6 males) were recruited walk on a 10-meter walkway randomly barefoot, MBFT neutral running shoes at their comfortable walking speed. Kinetic kinematic data collected using an 8-camera motion capture system. Data of joint angles, forces, moments extracted compute consecutive symmetry index. Compared led worse...
Barefoot technology shoes are becoming increasingly popular, yet modifications still needed. The present study aims to gain valuable insights by comparing barefoot walking neutral shoe in a healthy youth population.28 university students (22 females and 6 males) were recruited walk on 10-meter walkway both running at their comfortable speed. Full step cycle kinematic kinetic data collected using an 8-camera motion capture system.In the early stance phase, knee extension moment (MK1), first...
Profound malnutrition and immunodeficiency are serious negative effects of radiotherapy bone marrow transplantation for hematologic malignancy patients. This study aimed to evaluate the nutritional supplementation with a soy-whey protein mixture on hematopoietic immune reconstitution in an allogeneic transplant mouse model. Male BALB/c (H-2Kd) mice, 6-8 weeks-old, were divided randomly into five groups then provided different nutrition support. After 28 days, blood samples, marrow, spleen,...
<sec> <title>BACKGROUND</title> Maintaining compliance with personal preventive measures is important to achieve a balance of COVID-19 pandemic control and work resumption. </sec> <title>OBJECTIVE</title> The aim this study was investigate self-reported four prevent among sample factory workers in Shenzhen, China, at the beginning resumption China following outbreak. These included consistent wearing face masks public spaces (the workplace other settings); sanitizing hands using soap, liquid...
Transient ischemic attack (TIA) is a brief episode of cerebral ischemia. However, if symptom not presented as drop or hemiplegia, and alarming to the patient physician, how short duration would raise concern physician for TIA? It will be more complicated location neurological deficit vagrant. This report highlights rare TIA case which very migratory patchy distribution numbness.A middle-aged gentleman was with recurrent numbness on right side body 2 months, lasting about 10 s. The erratic...