A5100656343- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Ultrasound and Hyperthermia Applications
- Pulmonary Hypertension Research and Treatments
- Transplantation: Methods and Outcomes
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Cardiac tumors and thrombi
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Ultrasound in Clinical Applications
- Cardiovascular Health and Disease Prevention
- Cardiomyopathy and Myosin Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Cardiovascular and Diving-Related Complications
- Advanced MRI Techniques and Applications
- Congenital Diaphragmatic Hernia Studies
- Vascular anomalies and interventions
- Cardiovascular Issues in Pregnancy
- COVID-19 Clinical Research Studies
Huazhong University of Science and Technology
2016-2025
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2012-2025
Union Hospital
2016-2025
Union Hospital
2016-2025
Fujian Normal University
2025
Shanghai Pulmonary Hospital
2025
Tongji University
2025
Nanchang University
2024
Wuhan University
2023-2024
Wuhan Union Hospital
2006-2024
Background: To investigate deep vein thrombosis (DVT) in hospitalized patients with coronavirus disease 2019 (COVID-19), we performed a single institutional study to evaluate its prevalence, risk factors, prognosis, and potential thromboprophylaxis strategies large referral treatment center. Methods: We studied total of 143 COVID-19 from January 29, 2020 February 2020. Demographic clinical data, laboratory including ultrasound scans the lower extremities, outcome variables were obtained,...
Abstract Background Brain metastasis (BrM) poses a significant challenge to the prognosis and quality of life for patients with non-small cell lung cancer (NSCLC). Gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system (CNS), has been implicated progression various tumors. However, its potential role BrM NSCLC underlying mechanisms remain largely unexplored. Methods A multi-omics approach combined vivo vitro experiments identified GABA as key target NSCLC....
Abstract Background Bedside lung ultrasound (LUS) has emerged as a useful and non-invasive tool to detect involvement monitor changes in patients with coronavirus disease 2019 (COVID-19). However, the clinical significance of LUS score COVID-19 remains unknown. We aimed investigate prognostic value COVID-19. Method The protocol consisted 12 scanning zones was performed 280 consecutive based on B-lines, consolidation pleural line abnormalities evaluated. Results median time from admission...
•A total of 870 patients admitted with COVID-19 were enrolled in nine countries.•LV size and function analyzed by a core lab AI.•LV RV dysfunction are common acute illness portend poor prognosis.•Age, lung disease, LDH, LVLS, RVFWS associated in-hospital mortality.•World regional LV/RV differences highlight patient acuity echo utilization. BackgroundThe novel severe respiratory syndrome coronavirus-2 virus, which has led to the global coronavirus disease-2019 (COVID-19) pandemic is known...
Congenital heart disease (CHD) is a severe health risk for newborns. Early detection of abnormalities in fetal cardiac structure and function during pregnancy can help patients seek timely diagnostic therapeutic advice, early intervention planning significantly improve survival rates. Echocardiography one the most accessible widely used tools diagnosis CHD. However, traditional echocardiography has limitations due to fetal, maternal, ultrasound equipment factors, highly dependent on skill...
The sympathoadrenergic system and its major effector PKA (protein kinase A) are activated to maintain cardiac output coping with physiological or pathological stressors. If how plays a role in hypertrophy (PhCH) CH (PaCH) not clear.
In patients with heart failure preserved ejection fraction (HFpEF), the impact of type 2 diabetes (T2D) on left ventricular global longitudinal strain (LV GLS) and its prognostic implications remains unclear. We aimed to evaluate LV function using two-dimensional (2D) three-dimensional (3D) speckle-tracking echocardiography in HFpEF without T2D, investigate significance. A total 335 were prospectively enrolled for echocardiographic evaluation. GLS was obtained 2D- 3D-speckle-tracking...
Nanobubbles with a size of less than 1 µm can be used as ultrasound contrast agents for diagnosis and drug/gene carriers therapy. However, the optimal method preparing uniform-sized nanobubbles is considered controversial. In this study, we developed novel biocompatible by performing differential centrifugation to isolate relevant subpopulation from parent suspensions. Compared modulating thickness phospholipid film without centrifugation, fabricated under conditions exhibited uniform bubble...
Severe functional tricuspid regurgitation is associated with adverse clinical outcomes. Conventional surgical risk for patients advanced stage high. Alternative approaches are therefore required.The purpose of this study was to investigate the feasibility, technical details, and midterm outcomes implantation a novel radial force-independent orthotopic transcatheter valve -the LuX-Valve- in severe regurgitation.The implantations LuX-Valve were performed six left-sided valvular surgery...
Myocardial ischemia/reperfusion injury (MIRI) is the leading cause of irreversible myocardial damage. A pivotal pathogenic factor (I/R)-induced cardiomyocyte ferroptosis, marked by iron overload and lipid peroxidation. However, impact droplet (LD) changes on I/R-induced ferroptosis unclear. In this study, an aggregation-induced emission probe, TPABTBP developed that used for imaging dynamic in LD during ferroptosis. exhibits excellent LD-specificity, superior capability monitoring lipophagy,...