Małgorzata Łobocka

ORCID: 0000-0003-0679-5193
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About
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Research Areas
  • Bacteriophages and microbial interactions
  • Plant Virus Research Studies
  • Microbial infections and disease research
  • Bacterial Genetics and Biotechnology
  • Genomics and Phylogenetic Studies
  • Plant and Fungal Interactions Research
  • Viral gastroenteritis research and epidemiology
  • Antibiotic Resistance in Bacteria
  • Polyamine Metabolism and Applications
  • Antimicrobial Resistance in Staphylococcus
  • Monoclonal and Polyclonal Antibodies Research
  • CRISPR and Genetic Engineering
  • Zoonotic diseases and public health
  • Amino Acid Enzymes and Metabolism
  • RNA and protein synthesis mechanisms
  • Bacillus and Francisella bacterial research
  • Legume Nitrogen Fixing Symbiosis
  • Vibrio bacteria research studies
  • Enzyme Structure and Function
  • Antifungal resistance and susceptibility
  • Insect Resistance and Genetics
  • Enzyme Catalysis and Immobilization
  • Redox biology and oxidative stress
  • Plant Pathogenic Bacteria Studies
  • Environmental and Biological Research in Conflict Zones

Institute of Biochemistry and Biophysics, Polish Academy of Sciences
2016-2025

Warsaw University of Life Sciences
2011-2021

University of Wisconsin System
2012

Zero to Three
2001

National Cancer Institute
1996-1999

National Institutes of Health
1996

Polish Academy of Sciences
1994

Imperial College London
1992

Abstract This article summarises the activities of Bacterial Viruses Subcommittee International Committee on Taxonomy for period March 2021−March 2022. We provide an overview new taxa proposed in 2021, approved by Executive Committee, and ratified vote Significant changes to taxonomy bacterial viruses were introduced: paraphyletic morphological families Podoviridae , Siphoviridae Myoviridae as well order Caudovirales abolished, a binomial system nomenclature species was established. In...

10.1007/s00705-022-05694-2 article EN cc-by Archives of Virology 2023-01-23

This article reports the changes to virus taxonomy approved and ratified by International Committee on Taxonomy of Viruses (ICTV) in March 2022. The entire ICTV was invited vote 174 taxonomic proposals Executive at its annual meeting July 2021. All were an absolute majority members. Of note, Study Groups have started implement new rule for uniform species naming that became effective 2021 mandates binomial 'Genus_name species_epithet' format with or without Latinization. As a result this...

10.1007/s00705-022-05516-5 article EN cc-by Archives of Virology 2022-08-23

Phage therapy is increasingly put forward as a “new” potential tool in the fight against antibiotic resistant infections. During “Centennial Celebration of Bacteriophage Research” conference Tbilisi, Georgia on 26–29 June 2017, an international group phage researchers committed to elaborate expert opinion three contentious related issues that are hampering clinical progress field therapy. This paper explores and discusses bacterial resistance, training presence prophages production strains...

10.3390/v10040178 article EN cc-by Viruses 2018-04-05

A universal taxonomy of viruses is essential for a comprehensive view the virus world and communicating complicated evolutionary relationships among viruses. However, there are major differences in conceptualisation approaches to classification nomenclature virologists, clinicians, agronomists, other interested parties. Here, we provide recommendations guide construction coherent taxonomy, based on expert scientific consensus. Firstly, assignments should be congruent with best attainable...

10.1371/journal.pbio.3001922 article EN public-domain PLoS Biology 2023-02-13

This article reports changes to virus taxonomy and taxon nomenclature that were approved ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2023. The entire ICTV membership was invited vote 174 taxonomic proposals had been Executive July 2022, as well a proposed revision Statutes. All revised Statutes majority voting membership. Of note, continued process renaming existing species accordance with recently mandated binomial format included gene transfer agents...

10.1007/s00705-023-05797-4 article EN cc-by Archives of Virology 2023-06-10

Abstract This article reports changes to virus taxonomy and taxon nomenclature that were approved ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2024. The entire ICTV membership was invited vote 203 taxonomic proposals had been Executive (EC) July 2023 at 55th EC meeting Jena, Germany, or second November 2023. All online vote. Taxonomic additions include one new phylum ( Ambiviricota ), class, nine orders, three suborders, 51 families, 18 subfamilies, 820...

10.1007/s00705-024-06143-y article EN cc-by Archives of Virology 2024-11-01

P1 is a bacteriophage of Escherichia coli and other enteric bacteria. It lysogenizes its hosts as circular, low-copy-number plasmid. We have determined the complete nucleotide sequences two strains thermoinducible mutant, c1-100. The genome (93,601 bp) contains at least 117 genes, which almost two-thirds had not been sequenced previously 49 no homologs in organisms. Protein-coding genes occupy 92% are organized 45 operons, four decisive for choice between lysis lysogeny. Four others ensure...

10.1128/jb.186.21.7032-7068.2004 article EN Journal of Bacteriology 2004-10-15

Partition modules stabilize bacterial plasmids and chromosomes by actively promoting their segregation into daughter cells. The partition module of plasmid P1 is typical consists a centromere site, parS , genes that encode proteins ParA ParB. We show ParB can silence flanking (to which binds), apparently polymerizing along the DNA from nucleation site at . Wild-type contacts an extensive region DNA; silencing-defective proteins, were found to be partition-defective, are less able spread....

10.1126/science.283.5401.546 article EN Science 1999-01-22

The taxonomy of viruses is developed and overseen by the International Committee on Taxonomy Viruses (ICTV), which scrutinizes, approves ratifies taxonomic proposals, maintains a list virus taxa with approved names (https://ictv.global). ICTV has approximately 180 members who vote simple majority. Taxon-specific Study Groups established have combined membership over 600 scientists from wider virology community; they provide comprehensive expertise across range known are major contributors to...

10.1099/jgv.0.001840 article EN Journal of General Virology 2023-05-04

In this article we compare the efficacy of different pharmacological agents (ranitidine, and omeprazole) to support phage transit from stomach distal portions gastrointestinal tract in rats. We show that a temporal modification environment animal may protect Twort-like therapeutic antistaphylococcal A5/80 (from bacteriophage collection Hirszfeld Institute Immunology Experimental Therapy PAS Wroclaw, Poland) inactivation by gastric juice effectively enough enable significant fraction orally...

10.3389/fmicb.2017.00467 article EN cc-by Frontiers in Microbiology 2017-03-23

In this article, we - the Bacterial Viruses Subcommittee and Archaeal of International Committee on Taxonomy (ICTV) summarise results our activities for period March 2020 2021. We report division former in two separate Subcommittees, welcome new members, a Chair Vice Chair, give an overview taxa that were proposed 2020, approved by Executive ratified vote particular, realm, three orders, 15 families, 31 subfamilies, 734 genera 1845 species newly created or redefined (moved/promoted).

10.1007/s00705-021-05205-9 article EN cc-by Archives of Virology 2021-08-21

Bacillus anthracis is an etiological agent of anthrax, a severe zoonotic disease that can be transmitted to people and cause high mortalities. Bacteriophages their lytic enzymes, endolysins, have potential therapeutic value in treating infections caused by this bacterium as alternatives or complements antibiotic therapy. They also used identify detect B. anthracis. Endolysins two Wbetavirus phages, J5a F16Ba which were described us recently, differ significantly from the best-known phage...

10.1007/s00253-023-12839-z article EN cc-by Applied Microbiology and Biotechnology 2024-01-09
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