A5033337912- Cell Image Analysis Techniques
- Medical Image Segmentation Techniques
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Advanced MRI Techniques and Applications
- AI in cancer detection
- Radiomics and Machine Learning in Medical Imaging
- Image Processing Techniques and Applications
- Cardiovascular Disease and Adiposity
- Birth, Development, and Health
- Cardiac Imaging and Diagnostics
- Advanced Electron Microscopy Techniques and Applications
- Advanced X-ray Imaging Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Medical Imaging Techniques and Applications
- Medical Imaging and Analysis
- Advanced Memory and Neural Computing
- Pediatric Hepatobiliary Diseases and Treatments
- Endoplasmic Reticulum Stress and Disease
- Lung Cancer Diagnosis and Treatment
- Sperm and Testicular Function
- Gallbladder and Bile Duct Disorders
- Anesthesia and Neurotoxicity Research
- Cardiovascular Function and Risk Factors
- Advanced Image and Video Retrieval Techniques
Hangzhou Dianzi University
2024-2025
Yunnan Investment Group (China)
2024
Shandong University of Traditional Chinese Medicine
2024
State Grid Corporation of China (China)
2017-2024
Capital Medical University
2017-2024
Southern University of Science and Technology
2024
Xuzhou Medical College
2024
Chengdu University
2023
Universitat Pompeu Fabra
2009-2021
Xinxiang Medical University
2019
Collagen export from the endoplasmic reticulum (ER) requires TANGO1, COPII coats, and retrograde fusion of ERGIC membranes. How do these components come together to produce a transport carrier commensurate with bulky cargo collagen? TANGO1 is known form ring that corrals we show here how this or fence assembled. Our data reveal organized by its radial interaction COPII, lateral interactions cTAGE5, TANGO1-short itself. Of particular interest finding recruits membranes for collagen via NRZ...
TANGO1 (transport and Golgi organization 1) interacts with CTAGE5 COPII components Sec23/Sec24 recruits ERGIC-53 (endoplasmic reticulum [ER]–Golgi intermediate compartment 53)–containing membranes to generate a mega-transport carrier for export of collagens apolipoproteins from the ER. We now show that TANGO1, at ER, assembles in ring encircles components. The C-terminal, proline-rich domains molecules are initially tilted onto coats but appear be pushed apart as grows. These findings lend...
While individual cardiac myocytes only have a limited ability to shorten, the heart efficiently pumps large volume-fraction thanks cell organization in complex 3D fibre structure. Subclinical subtle structural remodelling is often present before symptoms arise. Understanding and early detection of these changes crucial for diagnosis prevention. Additionally, personalized computational modelling requires knowledge on multi-scale structure whole vessels.We developed rapid acquisition together...
Background: In the era of increasingly successful corrective interventions in patients with congenital heart disease (CHD), global and regional myocardial remodeling are emerging as important sources long-term morbidity/mortality. Changes organization myocardium CHD, its mechanical properties, conduction, blood supply, result altered function both before after surgery. To gain a better understanding develop appropriate individualized treatment strategies, microscopic cardiomyocytes, their...
Abstract Background Due to the great heterogeneity of gastric cancer (GC), prognosis patients within a stage is very different. Therefore, it necessary identify high risk factors for postoperative recurrence and metastasis take appropriate therapeutic strategies improve patients. In this study, we aimed explore prognostic significance preoperative serum carcinoembryonic antigen (CEA), carbohydrate 19 − 9 (CA19-9) 72 4 (CA72-4) in with I, II III GC who underwent radical gastrectomy. Methods A...
The pathogenesis of temporomandibular joint osteoarthritis (TMJOA) is closely associated with mechanical friction, which leads to the up-regulation inflammatory mediators and degradation articular cartilage. Injectable drug-loaded microparticles have attracted widespread interest in intra-articular treatment TMJOA by providing lubrication facilitating localized drug delivery. Herein, a hyaluronic acid-based microparticle developed excellent properties, loading capacity, antioxidant activity,...
<ns3:p>Workflows are the keystone of bioimage analysis, and NEUBIAS (Network European BioImage AnalystS) community is trying to gather actors this field organize information around them. One its most recent outputs opening F1000Research gateway, whose main objective offer a channel publication for analysis workflows associated resources. In paper we want express some personal opinions recommendations related finding, handling developing workflows. </ns3:p><ns3:p> The emergence "big data” in...
This paper presents a technique to estimate and model patient-specific pulsatility of cerebral aneurysms over one cardiac cycle, using 3D rotational X-ray angiography (3DRA) acquisitions. Aneurysm pulsation is modeled as time varying B-spline tensor field representing the deformation applied reference volume image, thus producing instantaneous morphology at each point in cycle. The estimated obtained by matching multiple simulated projections deforming their corresponding original...
In the last few years, some of visionary concepts behind virtual physiological human began to be demonstrated on various clinical domains, showing great promise for improving healthcare management. current work, we provide an overview image- and biomechanics-based techniques that, when put together, a patient-specific pipeline management intracranial aneurysms. The derivation subsequent integration morphological, morphodynamic, haemodynamic structural analyses allow us extract models...
Our objective was to identify predictors of improved postthaw semen quality in men with testicular cancer banking sperm for fertility preservation. We reviewed 173 individual samples provided by 67 germ cell tumor (TGCT) who cryopreserved before gonadotoxic treatment between 1994 and 2010 at our tertiary university medical center. main outcomes measures were independent the greater total motile count (TMC) TGCT. Men NSGCT more likely be younger (P < 0.01) had high stage (II or III, P...
We present a method for detecting and segmenting yeast cells in bright field microscopy images from which are often almost transparent. A classifier is firstly trained to detect edges of interest. label cost model with cardinality constraints then simultaneously detects cell centers clusters edge points, using Integer Linear Programming. For noisy or partial clustering, an additional step contour fitting seeded watershed applied segmentation. Results demonstrate that our can consistently...
Objective The volume based procurement (VBP) program in China was initiated 2022. cost‐effectiveness of robotic arm assisted total knee arthroplasty is yet uncertain after the initiation program. objective study to investigate arm‐assisted and influence VBP its China. Methods a Markov model‐based study. Cases primary from January 2019 December 2021 were included retrospectively. A model developed simulate patients with advanced osteoarthritis. Manual arthroplasties compared for before...
The objective of this study is to investigate the feasibility detecting and quantifying 3D cerebrovascular wall motion from a single rotational x-ray angiography (3DRA) acquisition within clinically acceptable time computing estimated field for further biomechanical modeling wall.The whole cycle cerebral vasculature modeled using 4D B-spline transformation, which 2D + t image registration framework. performed by optimizing similarity metric between entire measured projection sequence...