A5048432336- Forensic and Genetic Research
- Environmental DNA in Biodiversity Studies
- Molecular Biology Techniques and Applications
- Forensic Anthropology and Bioarchaeology Studies
- Forensic Fingerprint Detection Methods
- Ethics in Clinical Research
- Diabetes and associated disorders
- Pain Management and Opioid Use
- Identification and Quantification in Food
- Diabetes Management and Research
- Plant Genetic and Mutation Studies
- S100 Proteins and Annexins
- Archaeological Research and Protection
- Neuropeptides and Animal Physiology
- Opioid Use Disorder Treatment
- Anesthesia and Pain Management
- Forensic Toxicology and Drug Analysis
- Electronic Health Records Systems
- Advanced Proteomics Techniques and Applications
- Mobile Health and mHealth Applications
- Radiation Effects and Dosimetry
- Forensic Entomology and Diptera Studies
- Drug Transport and Resistance Mechanisms
- Pancreatic function and diabetes
- Pain Management and Placebo Effect
MaineHealth
2025
University of Vermont
2025
University of Colorado Anschutz Medical Campus
2025
Queensland Police Service
2009-2024
University of Technology Sydney
2007-2010
Kingston General Hospital
1984-1999
Queen's University
1984-1986
University of Calgary
1984
Internal carotid artery infusion of bradykinin caused extensive breakdown the blood-brain barrier to protein as demonstrated by extravasation marker, horseradish peroxidase, into vessel walls and adjacent parenchyma. Pretreatment animals with indomethacin, trifluoperazine, or imidazole significantly reduced quantity abnormally permeable vessels determined light microscopy. By electron microscopy, it was that an intense increase in number pinocytotic vesicles segments, but no change...
An investigation was carried out to determine general staining and histochemical properties of rat atrial specific granules. It found that these granules may be demonstrated using aldehyde fuchsin after pretreatments which involve oxidation or thiosulfation. This new way demonstrating is compared other methods in terms sensitivity selectivity as well the nature reactive groups involved reactions. No lipid carbohydrate were detected histochemically. Overall assessment reactions suggests are a...
For decades, researchers have utilized paper card studies to assess primary care clinician (PCC) perceptions across various clinical and practice topics. Since 2022, cards can be completed electronically through the electronic health record (EHR) or a novel smartphone application (app). These delivery modalities not previously been evaluated head-to-head. We report findings from work in progress comparing paper, EHR, app-delivered cards. The Northern New England CO-OP Practice Community...
Background: The purpose of this study was to collect 1 year real-world data from individuals with type diabetes (T1D) initiating the Medtronic 670G hybrid closed-loop insulin delivery system as part usual care. We sought expand current knowledge understand how use impacts patient-reported outcomes, in addition clinical for children and adults T1D. Methods: Questionnaires were completed by participant (and/or parent) before initiation (baseline) at 6 weeks, months, 12 months enrollment....
Understanding casework DNA recovery rates per evidence type is crucial for advancing forensic methodologies and practices. This study assesses profile data 17 firearm parts (including cartridges, bullets cases: CBCs) using New South Wales firearms from 2015 to 2019. CBCs were further classified as shotgun or metallic cartridges unfired fired. Quantitative analysis showed that the least was recovered hammer, safety CBCs, while a single swab of multiple resulted in highest recovery. Shotgun...
Forensic DNA Phenotyping (FDP) is an established but evolving field of testing. It provides intelligence regarding the appearance (externally visible characteristics), biogeographical ancestry and age unknown donor and, although not necessarily a requirement for its casework application, has been previously used as method last resort in New South Wales (NSW) Police Force investigations. FDP can further assist law enforcement agencies by re-prioritising existing pool suspects or generating...
The manufacture and distribution of fraudulent identity documents (IDs) is a pervasive prolific crime problem, enabling the activities organized networks terrorist cells. As reactive policing methods are ill-equipped to handle transversal repetitive nature document fraud, in 2012 Baechler et al. suggested complementary method that uses systematic profiling comparison IDs identify those produced by same source. While this has been successful Europe, it yet be implemented worldwide, there...
The successful application of Forensic Investigative Genetic Genealogy (FIGG) to the identification unidentified human remains and perpetrators serious crime has led a growing interest in its use internationally, including Australia. Routinely, FIGG relied on generation high-density single nucleotide polymorphism (SNP) profiles from forensic samples using whole genome array (WGA) (∼650,000 or more SNPs) sequencing (WGS) (millions for DNA segment-based comparisons commercially available...
In 2004, a survey was sent to forensic organisations in every jurisdiction Australia and New Zealand, benchmarking practices relation trace DNA analysis. Concerning issues were identified such as lack of standard training protocols, little ongoing or proficiency testing, poor information gathering sharing. To assess the changes occurring five years since this survey, follow-up devised distributed same early 2009. Seventy-seven surveys received from persons active field including crime scene...
The recovery of trace DNA from cartridge cases is common interest across many jurisdictions. Soaking offers improved profiling success rates over traditional methods. We evaluated the effects firing, calibre, and metal composition on controlled handled samples utilizing a soaking method. Our results show that firing decreases quantities recoverable higher are nickel ammunition compared to brass. In spiked samples, calibre had no significant effect recovery. Despite slight moderate...
ABSTRACT The effect of desipramine, imidazole, thioridazine and trifluoperazine on blood-brain barrier(BBB) permeability after a 24 hour cold lesion was studied in rats. Changes BBB were determined using quantitative horseradish peroxidase (HRP) assay. four drugs tested did not alter the quantity HRP cortex control animals, or contralateral test animals. However, desipramine significantly reduced extravasation around lesion. Several mechanisms for this are suggested; one possible mechanism...