This article aims to examine how certain economic and social factors influence short- long-term performance of small medium enterprises (SMEs). SMEs' is defined by using the value added (VA) SMEs, as a percent total VA enterprises. The study targets European Union (EU) countries selected authors following cluster analysis procedure. In order obtain influences, an that carries out three types tests conducted: testing stationarity, cointegration causality between indicators identified...

Chemotherapy (CT) resistance in ovarian cancer is related to multiple factors, and assessment of these factors necessary for the development new drugs therapeutic regimens. In an effort identify such determinants, we evaluated expression approximately 21,000 genes using DNA microarray screening paired tumor samples taken prior after CT treatment from 6 patients with predominantly advanced stage, high-grade epithelial cancer. A subset differentially expressed was selected all data by initial...

Context.—Breast cancer is increasingly treated with neoadjuvant chemotherapy to improve surgical resectability and evaluate tumor response, which assessed histopathologically. Several histopathologic classification systems have been previously described for assessment of treatment response. Objectives.—To test performance in a side-by-side comparison several after clinical outcome. Design.—Sixty-two patients were enrolled randomized trial receiving sequential doxorubicin paclitaxel....

Recently, there have been significant changes in the labour market and lives of employees, as modern society adapts increasingly easily to implementation artificial intelligence tools.However, technological also created challenges, including a gap between available required competencies use technologies.This study aims analyse relationships employee effectiveness tools, order highlight set essential effective interaction with technology.Therefore, achieve purpose research, questionnaire was...

The COVID-19 pandemic has resulted in the imposition of certain changes management organizations and behavior actions employees. purpose this paper is to investigate impact effects on employees' health mental well-being, as well their working performance. Moreover, aims highlight whether health- work-related stress factors mediate above relations. For data collection, a structured questionnaire was used. first results study showed that felt by employees did not directly affect physical...

The paper presents the impact of digital transformation on organizations.It outlines specific details management functions and protective actions with particular emphasis information security.The function is analyzed thought pillars primary activities that managers perform in order to achieve organizational goals.The key (foresight, planning, organizing, leading, controlling) are interrelated interdependent, effective requires a balanced approach all including cybersecurity procedures.The...

Despite the increasing emphasis placed on knowledge management (KM) by business sector and common belief that creating, acquiring, sharing, use of enable individuals, teams, communities to achieve superior performance, within healthcare context, there is still room from improvements both theoretical empirical perspectives. The purpose this paper outline contribution KM process social- economic-related outcomes in context health organizations. Given approach considered concepts their...

Purpose The current study has a two-fold purpose. Firstly, it aims to analyze the extent which knowledge management (KM) affects performance of individuals (task and contextual) on one hand that organizations (product or service, perceived financial) other hand. Secondly, proposes investigate mediating effect motivation innovation in relationship between KM individual organizational performance. Design/methodology/approach Partial least squares structural equation modeling (PLS-SEM) was...

Protein glycosylation perturbations are implicated in a variety of diseases, including cancer. Aberrant cancer is frequently attributed to altered expression polypeptide GalNAc transferases (GalNAc‑Ts) - enzymes initiating mucin-type O-glycosylation. A previous study from our group demonstrated that one member this family (GALNT3) overexpressed epithelial ovarian (EOC), and GALNT3 correlated with shorter progression-free survival (PFS) EOC patients advanced disease. As considerable degree...

Corporate social responsibility (CSR) is a trend that manifests on global level. The positive effects of CSR initiatives depend the reaction stakeholders, among which customers represent an important category. purpose this paper was to analyse impact cosmetics companies have customer behaviour in both short-term (buying intention) and long-term (client loyalty) case electronic commerce. Starting from existing literature, conceptual model proposed different dimensions as influencers (legal...

As far as students are concerned, there is a well-founded relationship between academic performance and career management from which special professional path can result, based on the multitude of knowledge, skills, experiences acquired during years study. To this end, presence help teachers participating in learning process, teaching activities they involved in, their own participation determinant factors. This research aims to highlight impact that above factors have future students. For...

Artificial intelligence (AI) is an increasingly notable presence in society, industries, and organizations, making its necessity felt more managerial decisions practices. This paper aims to outline the importance of topic related increase adaptability, agility, resilience management system as a result AI integration, resorting bibliometric type research. A total 107 papers from period 2007–2024 exported Web Science Core Collection database were analyzed, with support Biblioshiny software....

Tourism is an evolving phenomenon that integrates economic, social, cultural, and environmental dimensions, enabling a country's economic progress cultural exchange. Also, how people behave when they travel do it can represent useful information for both government agencies the business environment. The purpose of this research to observe preferences Romanian tourists regarding trips make on national territory, considering specifics trends characteristic practices each category belong to. To...

This study examines the perceived relationships between circular economy practices, procurement strategies, and organizational competitiveness using a theory-driven model survey data from future business professionals. Drawing on multiple theoretical perspectives, research explores how practices strategies influence investigates mediating moderating roles of culture, stakeholder pressure, resource availability, innovation, industry characteristics. The findings suggest that not only...

Maintenance of cellular homeostasis and xenobiotic detoxification is mediated by 19 human UDP-glucuronosyltransferase enzymes (UGTs) encoded ten genes that comprise the glucuronidation pathway. Deep RNA sequencing major metabolic organs exposes a substantial expansion UGT transcriptome alternative splicing, with variants representing 20% to 60% canonical transcript expression. Nearly fifth expressed in-frame sequences may create distinct structural functional features. Follow-up cell-based...

Chemotherapy (CT) resistance in ovarian cancer is broad and encompasses diverse, unrelated drugs, suggesting more than one mechanism of resistance. We aimed to analyze the gene expression patterns primary serous epithelial (EOC) samples displaying different responses first-line CT an attempt identify specific molecular signatures associated with response CT. Initially, profiles 15 chemoresistant EOC tumors [time recurrence (TTR) </=6 months] 10 chemosensitive (TTR > or =30 months) were...