A5018992469- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Heart Rate Variability and Autonomic Control
- Muscle activation and electromyography studies
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Dental Radiography and Imaging
- Infrared Thermography in Medicine
- Transcranial Magnetic Stimulation Studies
- Multiple Sclerosis Research Studies
- Animal Behavior and Reproduction
- Advanced Chemical Sensor Technologies
- Orthodontics and Dentofacial Orthopedics
- Insect and Arachnid Ecology and Behavior
- Postharvest Quality and Shelf Life Management
- Turtle Biology and Conservation
- Advanced Neuroimaging Techniques and Applications
- Stroke Rehabilitation and Recovery
- Neuroscience and Neural Engineering
- Morphological variations and asymmetry
- Plant and animal studies
- Photoreceptor and optogenetics research
University of Trento
2016-2020
Politecnico di Milano
2007-2017
University of L'Aquila
2012-2013
Istituto di Fotonica e Nanotecnologie
2009
Performance assessment of instruments devised for clinical applications is key importance validation and quality assurance. Two new protocols were developed applied to facilitate the design optimization time-domain optical brain imaging within European project nEUROPt. Here, we present “Basic Instrumental Performance” protocol direct measurement relevant characteristics. tests are discussed in detail. First, responsivity detection system a measure overall efficiency detect light emerging...
We have designed a compact dual wavelength (687 nm, 826 nm) multi-channel (16 sources, 8 detectors) medical device for muscle and brain imaging based on time domain functional near infrared spectroscopy. The system employs the space multiplexing approach to reduce cross-talk increase signal-to-noise ratio. System performances been tested homogeneous heterogeneous tissue phantoms following specifically protocols photon migration instruments. Preliminary in vivo measurements performed validate...
We evaluated frontal brain activation during a mixed attentional/working memory task with graded levels of difficulty in group 19 healthy subjects, by means time-domain functional near-infrared spectroscopy (fNIRS). Brain was assessed, and load-related oxy- deoxy-hemoglobin changes were studied. Generalized linear model (GLM) applied to the data explore metabolic processes occurring mental effort and, possibly, their involvement short-term memorization. GLM twice: for modeling as whole...
Neuroimaging studies have shown neuromuscular electrical stimulation (NMES)-evoked movements activate regions of the cortical sensorimotor network, including primary cortex (SMC), premotor (PMC), supplementary motor area (SMA), and secondary somatosensory (S2), as well prefrontal (PFC) known to be involved in pain processing. The aim this study, on nine healthy subjects, was compare network activation profile ratings during NMES right forearm wrist extensor muscles at increasing current...
The relationship between white matter injury and cortical atrophy development in relapsing-remitting multiple sclerosis (RRMS) remains unclear.To investigate the associations corticospinal tract integrity morphology measures of primary motor cortex RRMS patients healthy controls.51 30 controls underwent MRI examination for reconstruction assessment integrity. Partial correlation linear regression analyses were used to focal normal appearing (NAWM) with thickness surface area cortex....
Abstract Theory predicts that social interactions can induce an alignment of behavioral asymmetries between individuals (i.e., population-level lateralization), but evidence for this effect is mixed. To understand how interaction with other affects asymmetries, we systematically manipulated the environment Drosophila melanogaster , testing individual flies and dyads (female-male, female-female male-male pairs). In these contexts measured population in behaviors (circling asymmetry, wing use)...
This review is an introduction to functional near infrared spectroscopy techniques and instrumentation which are commonly used for the estimation of haemoglobin concentration in muscle brain cortex. Three approaches considered: continuous wave, frequency domain time spectroscopy. The different briefly analysed from a theoretical point view order understand their capabilities drawbacks. Some considered, presenting main characteristics techniques, similarities principal differences.
We designed and developed a compact dual-wavelength dual-channel time-resolved system for near-infrared spectroscopy studies of muscle brain. The employs pulsed diode lasers as sources, photomultipliers, time-correlated single photon counting boards detection. To exploit the full temporal dynamic range acquisition technique, we implemented an approach based on wavelength space multiplexing: laser pulses at two wavelengths are alternatively injected into channels by means optical 2×2 switch....
By exploiting a multichannel portable instrument for time-domain near-infrared spectroscopy (TD-NIRS), we characterized healthy neonates' brains in term of optical properties and hemodynamic parameters. In particular, assessed the absolute values absorption reduced scattering coefficients at two wavelengths, together with oxy-, deoxy- total hemoglobin concentrations, blood oxygen saturation brains. this study, 33 full-term neonates were tested, obtaining following median values: 0.28...
Purpose: Sustained attention is one of the most important cognitive abilities for management everyday life, but it often studied only at behavioral level, while functional correlates are scarcely investigated. In this article, authors address topic characterizing dynamics cerebral metabolism in prefrontal cortex during a task prolonged attention. Method: By means multichannel time‐resolved near‐infrared spectroscopy and generalized linear model based data processing, measured hemodynamic...
Mental processes bring about neural, vascular and autonomic changes in the brain cortex. Due to different nature of these modifications, their onsets show no synchrony time dynamics is often strongly dissimilar. After acquiring data from a group 16 subjects, we estimated temporal correlation between task signals order assess possible influences induced by an attentive on electroencephalographic (EEG), heart rate variability (HRV), oxy- deoxy-haemoglobin concentration signals. We also...
We evaluated neurovascular and autonomic response to a Divided Attention task within group of 16 healthy subjects, by means Electroencephalography, Electrocardiography, functional Near Infrared Spectroscopy techniques, acquired simultaneously. exctracted Alpha (8-13,5 Hz) Beta (13,5-30 power rhythms with spectral autoregressive residual model, inter-beat-interval (RR series) separated superficial (extracortical) depth NIRS contribution. Cross Correlation Function at different time lags was...
We developed and optimized a multichannel dual-wavelength time-domain brain oximeter for functional studies in the clinical environment. The system, mounted on 19"-rack, is interfaced with instrumentation monitoring physiological parameters stimuli presentation.
To facilitate the design and optimization of instruments for time-domain optical brain imaging within European project "nEUROPt", performance various is assessed compared. This type relies on picosecond lasers with high repetition rates, fast detectors time-correlated single photon counting. The first step assessment included a number basic tests that are related to parameters source, differential nonlinearity timing electronics temporal instrument response function (IRF). An additional test...
We recorded maps of cortical and systemic hemodynamic responses (oxy-hemoglobin, O<sub>2</sub>Hb deoxy-hemoglobin, HHb) during incremental neuromuscular electrical stimulation (NMES) the right forearm in nine subjects by a 32- channel time domain fNIRS (TD-fNIRS) instrument. Statistical parametric (SPM) relative to different current stimulations (under over maximal tolerated intensity-MTI) versus 10%MTI were generated. Exploiting temporal information contained TD-fNIRS signal it was possible...
ISHS II WOCMAP Congress Medicinal and Aromatic Plants, Part 2: Pharmacognosy, Pharmacology, Phytomedicine, Toxicology PROTEOLYTIC ENZYMES FROM THE LATEX OF MORRENIA ODORATA (HOOK ET ARN.) LINDLEY (ASCLEPIADACEAE)
We evaluated frontal brain activation during a working memory task with graded levels of difficulty in group 19 healthy subjects, by means time-resolved fNIRS technique. Brain was computed, and then separated into "block-related" "tonic" components. Load-related increases blood oxygenation were studied for the four different difficulty. Generalized Linear Models applied to data order explore metabolic processes occurring mental effort and, possibly, their involvement short term memorization....