Shujun Zhang

ORCID: 0000-0003-0719-8534
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Research Areas
  • Natural product bioactivities and synthesis
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Traditional Chinese Medicine Analysis
  • Phytochemistry and Biological Activities
  • Ear Surgery and Otitis Media
  • Bone Tissue Engineering Materials
  • Medicinal plant effects and applications
  • Medical Imaging and Analysis
  • Silk-based biomaterials and applications
  • Esophageal Cancer Research and Treatment
  • Ear and Head Tumors
  • Extracellular vesicles in disease
  • Nerve injury and regeneration
  • Shoulder and Clavicle Injuries
  • Acupuncture Treatment Research Studies
  • Cancer-related molecular mechanisms research
  • Trauma Management and Diagnosis
  • Foot and Ankle Surgery
  • Hydrogen's biological and therapeutic effects
  • Moyamoya disease diagnosis and treatment
  • Nasal Surgery and Airway Studies
  • Bioactive Natural Diterpenoids Research
  • Tracheal and airway disorders
  • Biological Activity of Diterpenoids and Biflavonoids

Shanxi University of Traditional Chinese Medicine
2024

Affiliated Hospital of Jining Medical University
2024

Wuhan Puai Hospital
2017-2023

Soochow University
2021-2023

Institute of Chemistry
2011-2022

Qiqihar University
2011-2022

Harbin Institute of Technology
2022

Wuxi No.2 People's Hospital
2021

Second Hospital of Shandong University
2018-2020

Huazhong University of Science and Technology
2017

Exosomal long non-coding RNAs (lncRNAs) have been recognised as promising stable biomarkers in cancers. The aim of this study was to identify an exosomal lncRNA panel for diagnosis and prognosis esophageal squamous cell carcinoma (ESCC).Exosomes were isolated from serum by ExoQuick Solution. To validate the exosomes, markers characterization nanoparticle performed. Quantitative real-time PCR used measure levels lncRNAs exosomes ESCC patients healthy subjects. In training set, profiles 404...

10.2147/cmar.s250971 article EN cc-by-nc Cancer Management and Research 2020-10-01

Medical sutures with sustainable antibacterial properties can effectively inhibit pathogens, thus avoiding the occurrence of surgical site infection and reducing recurrence patients resulting in postoperative death. This paper describes a facile scalable suture function fair mechanical biocompatible using simple, efficient, eco-friendly method. Silk filaments were braided into core–shell structure braiding machine, then silk fibroin (SF) films loaded different percentages berberine (BB)...

10.1021/acsbiomaterials.1c00481 article EN ACS Biomaterials Science & Engineering 2021-05-27

Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) been used for the treatment of KOA more than one thousand years, but its treating not revealed. In our previous study, we confirmed that DHJST inhibited activation NLRP3 signaling in rats humans. current aimed determine how inhibits alleviate knee cartilage damage.Mice were injected with shRNA or Notch1-overexpressing adenovirus into tail vein...

10.1186/s13020-023-00784-y article EN cc-by Chinese Medicine 2023-06-29

Background The angiographic features of moyamoya disease (MMD) and atherosclerosis‐associated vasculopathy (AS‐MMV) are similar, but the etiology clinical treatment strategies different. Differentiating MMD from AS‐MMV helps to choose appropriate treatment. Purpose To investigate feasibility a nomogram based on high‐resolution vessel wall (HR‐VWI) MRI differentiate AS‐MMV. Study Type Retrospective. Subjects One hundred two patients with (N = 52) or 50) in training cohort (9–72 years; 54...

10.1002/jmri.29407 article EN Journal of Magnetic Resonance Imaging 2024-05-09

Abstract Peripheral nerve injures have long been a tricky problem in surgery and feasible treatment is the transplantation of guidance conduits (NGCs). This study presents two‐layer composite NGC with fair mechanical properties good biocompatibility. The inner layer was made degummed silk yarns/magnesium wires using braiding technology, outer from mixed solution fibroin/chitosan (SF/CS) freeze‐drying treatment. Orthogonal experimental design applied to rationally braided structural obtain...

10.1002/jbm.a.37426 article EN Journal of Biomedical Materials Research Part A 2022-07-14

The chemical constituents from Euphorbia lunulata was investigated in this paper. Fourteen compounds were isolated and purified by column chromatographies on silica gel preparative HPLC. Their structures identified physiochemical properties NMR data analysis as lupeol (1), euphol (2), cassipourol(3) , 24-methylenecycloartan-3beta-ol (4), 24-hydroperoxycycloart-25-en-3beta-ol (5), 25-hydroperoxycycloart-23-en-3beta-ol (6), betulin (7), uvaol (8), (23E) -25-methoxycycloart-23-en-3beta-ol (9),...

10.4268/cjcmm20141227 article EN China Journal of Chinese Materia Medica 2014-06-15

In the last decade, there has been an increasing use of biomaterial patches in regeneration traumatic tympanic membrane perforations. The major advantages are to provisionally restore physiological function middle ear, thereby immediately improving ear symptoms, and act as a scaffold for epithelium migration. However, whether additional biological effects on eardrum is unclear material patching clinic.This study evaluated healing response different repair patterns human perforations by...

10.1016/j.bjorl.2017.06.011 article EN cc-by Brazilian Journal of Otorhinolaryngology 2017-08-03

To explore the diagnostic and prognostic values of Sirtuin 6 (SIRT6) Vanin-1 (VNN1) in peripheral blood monocytes children with primary nephrotic syndrome (PNS) their correlation acute kidney injury (AKI).

10.62347/touh6376 article EN American Journal of Translational Research 2024-01-01

To explore the correlation between serum interleukin-22 (IL-22) and interleukin-27 (IL-27) levels vasculopathy in patients with diabetic nephropathy (DN).

10.62347/dupc2324 article EN American Journal of Translational Research 2024-01-01

// Jie Liang 1 , Guodong Li 1, 2 Jun Xu 3 Tong Wang 5 Yanyan Jia 4 Qinghua Zhai Lihua Qiao Miao Chen Yajing Guo and Shujun Zhang Department of Medical Records Statistics, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China Hospital Administration, General Surgery, Follow-up, Health School Public Health, University, Correspondence to: Li, email: 314350829@qq.com Xu, xujun_sxth@sina.com Keywords: ESCC; hypertension; hypoxia; VEGF; esophagectomy Received: June 22, 2017 Accepted: December...

10.18632/oncotarget.23774 article EN Oncotarget 2017-12-30

Silica gel column chromatography and preparative HPLC were applied to isolate the chemical constituents from roots of Ixeris chinensis. Fifteen compounds isolated their structures elucidated by physicochemical properties spectral analysis as chinensioide G(1), B(2), 10α-hydroxy-guaia-12,6-lactone-3-keton(3), C(4), 10α-hydroxy-11βH-guaia-4(5) -ene-12,6-lactone (5), 3β, 10α-dihydroxy-11βH-guaia-11 (13)-ene-12,6-lactone (6), 10α-dihydroxy-4βH, 11βH-guaia-12,6-lactone(7), 10α-dihydroxy-guaia-4...

10.4268/cjcmm20141617 article EN China Journal of Chinese Materia Medica 2014-08-15

Twenty-three morphometric fruit traits for common pear (Pyrus communis L.) cultivars and hybrids were recorded from trees growing in the tree resources nursery of Yantai Academy Agricultural Sciences, Shandong, China, to provide mon cultivars.The frequency distribution, co--Weaver diversity index calculated.A Q-mode cluster analysis principal component used evaluate groups among accessions pomological charobserved accessions.The Shannon-Weaver cient variation was lowest total soluble solids...

10.17660/ejhs.2022/019 article EN European Journal of Horticultural Science 2022-04-25

To study the value of a retrograde flow sign and collateral circulation on CT angiography (CTA) for differential diagnosis chronic total occlusion from subtotal femoropopliteal artery (FPA). 50 patients with obstruction FPA underwent CTA digital subtraction examinations lower limbs. The frequency in was noted analyzed, results as standard to judge or occlusion. decreasing distal proximal direction suggests existence flow.There were significant differences occurrence rates groups (X2 = 13.1,...

10.1259/bjr.20170016 article EN cc-by-nc British Journal of Radiology 2017-07-14
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