- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Computational Drug Discovery Methods
- Tuberculosis Research and Epidemiology
- Microbial Community Ecology and Physiology
- Synthesis and biological activity
- Metal complexes synthesis and properties
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Crystallography and molecular interactions
- SARS-CoV-2 and COVID-19 Research
- Aquaculture disease management and microbiota
- Biochemical and Molecular Research
- Hepatitis C virus research
- Ruminant Nutrition and Digestive Physiology
- RNA and protein synthesis mechanisms
- Peptidase Inhibition and Analysis
- Microbial Fuel Cells and Bioremediation
- Pesticide Exposure and Toxicity
- ATP Synthase and ATPases Research
- COVID-19 Clinical Research Studies
- Heat shock proteins research
- Herbal Medicine Research Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Genetics and Biotechnology
National Forensic Sciences University
2021-2023
Central Forensic Science Laboratory
2023
Hemchandracharya North Gujarat University
2012-2021
Veer Narmad South Gujarat University
2019-2020
A decade since the availability of Mycobacterium tuberculosis (Mtb) genome sequence, no promising drug has seen light day. This not only indicates challenges in discovering new drugs but also suggests a gap our current understanding Mtb biology. We attempt to bridge this by carrying out extensive re-annotation and constructing systems level protein interaction map with an objective finding novel target candidates. Towards this, we synergized crowd sourcing social networking methods through...
We report Metagenome from the saline desert soil sample of Little Rann Kutch, Gujarat State, India. consisted 633,760 sequences with size 141,307,202 bp and 56% G + C content. sequence data are available at EBI under Metagenomics database accession no. ERP005612. Community metagenomics revealed total 1802 species belonged to 43 different phyla dominating Marinobacter (48.7%) Halobacterium (4.6%) genus in bacterial archaeal domain respectively. Remarkably, 18.2% a poorly characterized group...
Pneumonia of unknown cause detected in Wuhan, China was first reported to the WHO Country Office on 31 December 2019. The outbreak declared a Public Health Emergency International Concern 30 January 2020. Currently, there is no Vaccine against COVID-19 pandemic and infection spreading worldwide vary rapidly an exigent requirement practicable drug treatment. Drug repurposing one most promising approaches for that. Many reports are available with silico but majority them engrossed single...
Aedes mosquitoes are the major cause of several vector-borne diseases in tropical and subtropical regions. Synthetic pesticides against these have certain limitations; hence, natural, eco-friendly, safe larvicides obtained from plant resources used to overcome these. In present study, larvicidal efficiency Commiphora wightii fourth instar stage dengue fever mosquito aegypti (Linnaeus, 1762) was studied. The gum resin C. collected using borehole tapping method, hexane extracts different...
Pneumonia of unknown cause detected in Wuhan, China was first reported to the WHO Country Office on 31 December 2019. The outbreak declared a Public Health Emergency International Concern 30 January 2020. Currently, there is no Vaccine against COVID-19 pandemic and infection spreading worldwide vary rapidly an exigent requirement practicable drug treatment. Drug repurposing one most promising approaches for that. Many reports are available with silico but majority them engrossed single...
Abstract A new series of Zn II metal complexes ligands 4‐(4‐chlorobenzoyl)‐5‐methyl‐2‐phenyl‐2,4‐dihydro‐3H‐pyrazol‐3‐one (PCBPMP) and 4‐(4‐chlorobenzoyl)‐5‐methyl‐2‐(p‐tolyl)‐2,4‐dihydro‐3H‐pyrazol‐3‐one (PCBTPMP) were prepared characterized. The nature bonding the stereochemistry deduced from 1 H 13 C Nuclear Magnetic Resonance (NMR), Fourier‐transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), Molar conductivity measurements Single‐crystal X‐ray diffraction. analyses...
<p>Pneumonia of unknown cause detected in Wuhan, China was first reported to the WHO Country Office on 31 December 2019. The outbreak declared a Public Health Emergency International Concern 30 January 2020. Currently, there is no Vaccine against COVID-19 pandemic and infection spreading worldwide vary rapidly an exigent requirement practicable drug treatment. Drug repurposing one most promising approaches for that. Many reports are available with <i>in silico</i> but...
Salinicoccus sp. BAB 3246 is a halophilic bacterium isolated from marine water sample collected the coastal region of Gujarat, India, surface stream. Based on 16sRNA sequencing, organism was identified as (Genebank ID: KF889285). The present work performed to determine whole genome sequence using Ion Torrent PGM platform followed by assembly CLC genomics workbench and annotation RAST, BASys MaGe. complete 713,204 bp with second largest size for reported in NCBI database. A total 652...
Cholera, a disease caused by the Vibrio cholerae bacteria, threatens public health worldwide. The organism mentioned above has significant historical record of being identified as prominent aquatic environmental pollutant capable adapting its phenotypic and genotypic traits to react host patients effectively. This study aims elucidate heterogeneity sporadic clinical strain V. VC01 among residing in Silvasa. involved conducting whole-genome sequencing isolate obtained from exhibiting...
SARS-CoV-2 is an RNA coronavirus responsible for Acute Respiratory Syndrome (COVID-19). In January 2021, the re-occurrence of COVID-19 infection was at its peak, considered second wave epidemics. initial stage, it a double mutant strain due to two significant mutations observed in their Spike protein (E484Q and L452R). Although first detected India later on, spread several countries worldwide, causing high fatality this strain. present study, we investigated spreading B.1.617 worldwide...