Jaymesh Thadani

ORCID: 0000-0003-4268-5549
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About
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Research Areas
  • Mesenchymal stem cell research
  • Adipose Tissue and Metabolism
  • Natural Antidiabetic Agents Studies
  • Antioxidant Activity and Oxidative Stress
  • Osteoarthritis Treatment and Mechanisms
  • Hematopoietic Stem Cell Transplantation
  • Heme Oxygenase-1 and Carbon Monoxide
  • Selenium in Biological Systems
  • Papaya Research and Applications
  • Aquatic life and conservation
  • Liver physiology and pathology
  • Nitric Oxide and Endothelin Effects
  • Hair Growth and Disorders
  • Protein Hydrolysis and Bioactive Peptides
  • Autoimmune Bullous Skin Diseases
  • Aquaculture Nutrition and Growth
  • Cell Adhesion Molecules Research
  • Traditional Chinese Medicine Analysis
  • Phytochemicals and Medicinal Plants
  • Biomedical Ethics and Regulation
  • Platelet Disorders and Treatments
  • Optimism, Hope, and Well-being
  • Tissue Engineering and Regenerative Medicine
  • Moringa oleifera research and applications
  • Enzyme Catalysis and Immobilization

Maharaja Sayajirao University of Baroda
2015-2020

Total (France)
2019

Indian Institute of Information Technology Vadodara
2017

Total (Belgium)
2014

Cardioprotective potential of anthocyanin rich red cabbage extract (ARCE) was assessed in H2O2 treated rat neonatal cardiomyoblasts (H9c2 cells) and isoproterenol (ISO) induced rodent model myocardial infarction. H9c2 cells recorded cytotoxicity (48–50%) apoptosis (57.3%), the same were reduced presence ARCE (7–10% & 12.3% respectively). Rats pretreated with for 30 days followed by ISO treatment favourable heart: body weight ratio as compared to group. Also, mRNA levels enzymatic...

10.1371/journal.pone.0182137 article EN cc-by PLoS ONE 2017-08-01

The significance of oxidative modification LDL in the pathogenesis atherosclerosis and lack efficient treatment intervention has led researchers to develop an effective therapy based on natural antioxidants. present study provides preliminary evidence support anti-atherosclerotic potential methanolic extract Cuminum cyminum L. (CC). We found that CC inhibited Cu2+ -mediated oxidation as demonstrated by ex vivo kinetic study, products (malondialdehyde, lipid hydroperoxide protein carbonyl),...

10.31254/phyto.2018.7116 article EN The Journal of Phytopharmacology 2018-01-22

Background: A number of papers describe different stem cell lines as the presenting feature to treat diabetes. Case Report: We report a 21 year old female with type 1 diabetes mellitus who was treated islet like aggregates (ICAs) translated from autologous adipose derived mesenchymal cells (ADMSCs). Half total count adipose-derived stromal vascular fraction (AD-SVF) injected intramuscularly. The other half purified ADMSCs and ICAs by intra-hepatic route. patient showed remarkable decrease in...

10.17659/01.2017.0064 article EN Journal of Case Reports 2017-07-05

Aim: The present study aims to compare the cytoprotective effect of Cuminum cyminum L. (CC) extract and cuminaldehyde (CA) against lipotoxicity induced by oxidized low density lipoprotein (Ox-LDL) in mouse macrophage (RAW 264.7) cells. Objective: To assess comparative Cytoprotective potential CC CA Ox-LDL cytotoxicity. ii) efficacy preventing apoptosis Methods: Protective aganist cytotoxicity RAW 264.7 cells was assessed MTT assay. DCFDA stain used check generation ROS followed analysis...

10.2174/2210315509666190624130123 article EN The Natural Products Journal 2020-03-16

Adipose derived autologous mesenchymal stem cells have been transplanted and tested for their ability to regenerate tissues several indications.While treating various age related neurodegenerative disorders with regenerative rejuvenating properties, we accidentally observed a transition of hair colorations from mostly grey black in all the 4 elderly patients.We given 20million intravenous also 20 million intrathecal, multiple sessions each patient.Though low dose effects were very obvious...

10.7243/2054-717x-2-3 article EN Stem Cell Biology and Research 2015-01-01

Abstract Background Stem cells are widely used for therapy including treatment of liver damage. Adipose-derived mesenchymal stem (ADMSCs) administered to treat fatty known improve function but their use is restricted due a poor success rate. This study investigates efficacy melatonin-primed ADMSCs (Mel. MSCs) in experimentally induced non-alcoholic disease (NAFLD). Results MSCs treated with LPS showed prominent DCFDA fluorescence as compared the untreated cells. Also, JC-1 staining had...

10.1186/s43066-021-00157-w article EN cc-by Egyptian Liver Journal 2021-12-21

Stem Cell therapeutics is a revolutionary change in the world of modern medicine. These magical bullets have evolved as alternative therapeutic modality to conventional method. Different countries passed legislation undertake human embryonic stem cell research. Developed like USA and, Australia banned exploration hESCs for research purpose. While on other hand, developing made stringent regulatory approvals and permitted To avoid ethical conspiracy, induced Pluripotent cells with same...

10.4172/2157-7633.1000403 article EN Journal of Stem Cell Research & Therapy 2017-01-01

Background: Conventional treatments of osteoarthritis demonstrate only modest clinical benefits without lesion reversal. Autologous mesenchymal stem cells (MSCs) are known to have potential for articular cartilage regeneration. We assess the feasibility and safety treating autologous MSCs in combination with platelet rich plasma (PRP). Material & Methods: Patients chronic knee pain unresponsive conservative showing radiological evidence were enrolled injected adipose derived...

10.17659/01.2017.0103 article EN Journal of Case Reports 2017-11-30
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