A5012289608- Natural product bioactivities and synthesis
- Protease and Inhibitor Mechanisms
- Bioactive Compounds in Plants
- Flavonoids in Medical Research
- Saffron Plant Research Studies
- Peptidase Inhibition and Analysis
Ruijin Hospital
2023
Shanghai Jiao Tong University
2023
Nanchang University
2022
Background Catestatin has been reported as a pleiotropic cardioprotective peptide. Heart failure with preserved ejection fraction (HFpEF) was considered heterogeneous syndrome complex cause. We sought to investigate the role of catestatin in HFpEF and diastolic dysfunction. METHODS AND RESULTS Administration recombinant (1.5 mg/kg/d) improved dysfunction left ventricular chamber stiffness transverse aortic constriction mice deoxycorticosterone acetate pellet implantation, reflected by...
As a kind of flavonoid, scutellarein is widely used to protect against various human diseases. Although the protective effects have been well studied, its influence on reproduction remains unknown. In this research, we evaluated effect sperm functions in vitro. Three different concentrations (1, 10, 100 μM) were applied ejaculated sperm. Fertilisation-essential functions, as intracellular calcium concentration ([Ca2+ ]i ) and protein-tyrosine phosphorylation, two factors which are vital for...