A5012720011- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Optical Coherence Tomography Applications
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Ocular Infections and Treatments
- Ophthalmology and Eye Disorders
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Drug-Induced Ocular Toxicity
- Cerebral Venous Sinus Thrombosis
- Corneal Surgery and Treatments
- Vascular Malformations Diagnosis and Treatment
- Connective tissue disorders research
- Connexins and lens biology
- Retinopathy of Prematurity Studies
- Ophthalmology and Visual Health Research
- Airway Management and Intubation Techniques
- Ocular Oncology and Treatments
- Advanced Algorithms and Applications
- Engineering Applied Research
- Retinal Development and Disorders
Centre for Sight
2023
Aravind Eye Hospital
2004-2022
Creative Commons
2022
L V Prasad Eye Institute
2022
Christie's
2020
Royal Devon & Exeter NHS Foundation Trust
2007
Norfolk and Norwich University Hospital
2006
Johns Hopkins University
1997
To establish the long-term, dose-response relationship between concentration of and duration exposure to mitomycin a decrease in intraocular pressure (IOP) fewer complications.We performed prospective double-masked, placebo-controlled, 1-year study evaluating IOP complications fornix-based trabeculectomy surgery 300 eyes equally divided among therapy with placebo; mitomycin, 0.2 mg/ mL, applied for 2 minutes; 0.4 mg/mL, 4 or minutes. All had vertical horizontal cup-disc ratios greater than...
To determine risk factors for lens opacities and age related cataract in an older rural population of southern India.A cross sectional based study 5150 people aged 40 years above from 50 clusters three districts India. The was graded classified after dilation using LOCS III system at the slit lamp cataract. Definite defined as nuclear opalescence >/=3.0 and/or cortical PSC >/=2.0.Definite cataracts were found 2449 (47.5%) subjects prevalence increased with age. adjusted significantly lower...
To study the results of phacoemulsification in eyes with white cataract.Aravind Eye Hospital, Madurai, India.This retrospective comprised 212 consecutive patients cataract: 192 mature (90.6%), 11 intumescent (5.2%), and 9 hypermature (4.2%). Patients had continuous curvilinear capsulorhexis. After nucleus was removed by divide conquer or phaco chop technique, a posterior chamber intraocular lens implanted. Preoperative intraoperative findings, as well postoperative outcomes, were...
The objectives of the study were to (a) describe different types problems that patients in southern India reported having when taking their glaucoma medications and (b) examine relationship between patient reported-problems self-reported adherence. A survey was conducted by clinical staff on 243 who at least one medication an eye clinic India. We found 42% or more using medications. Approximately 6% being less than 100% adherent past week. Unmarried difficulty squeezing bottle opening...
Recently proposed deep learning (DL) algorithms for the segmentation of optical coherence tomography (OCT) images to quantify morphological changes optic nerve head (ONH) tissues during glaucoma have limited clinical adoption due their device specific nature and difficulty in preparing manual segmentations (training data). We propose a DL-based 3D framework that is easily translatable across OCT devices label-free manner (i.e. without need manually re-segment data each device). Specifically,...
Hermansky-Pudlak Syndrome (HPS) is a rare autosomal recessive lysosomal storage disorder characterized by oculocutaneous albinism, bleeding diathesis and in some cases pulmonary fibrosis, granulomatous colitis. While genetic alterations HPS genes are known to cause the disorder, we explored variations associated with an individual clinical manifestations of HPS. We present 58-year-old female patient from Southern India, born consanguineous parents, who presented features Whole-exome...
<h3>Purpose</h3> To estimate the prevalence of uveitis in rural Tamil Nadu, India. <h3>Methods</h3> Cluster sampling identified a population-based sample 5150 persons ages 40 years and older, representative three districts Each received comprehensive dilated ocular examination by an ophthalmologist, results were registered on forms requiring responses about presence inflammatory signs diagnoses. Potential cases confirmed consensus two specialists, upon review study medical records. Crude...
Glaucoma is a major cause of blindness in developing nations. Medical and laser therapy have limitations this environment. Filtration surgery alone often fails young, darkly pigmented, individuals. The authors, therefore, evaluated the safety efficacy filtration surgery, using topical mitomycin C, patients undergoing trabeculectomy India.A short-term pilot study used C at time population southern Indians with various forms glaucoma. A single 5-minute intraoperative application 0.4 mg/ml was...
To compare initial glaucoma therapy with medications and trabeculectomy in southern India.Patients aged ≥ 30 years newly diagnosed were randomized to 5-fluorouracil or medical therapy. Subjects best-corrected vision <6/18 due cataract underwent phacoemulsification (phaco/intraocular lens, IOL). Intraocular pressure (IOP), visual function assessed at 12 months.Patients assigned surgery received the expected 86% (172/199) 64% (126/199) of cases, respectively. Forty patients (20%) refused any...
We determined the incidence in a developing nation of posterior capsule rupture during planned extracapsular cataract surgery and insertion chamber intraocular lens. The results, part, determine whether this complication limits widespread utility procedure nations. retrospectively reviewed charts all patients undergoing 6-month period; received as inpatients at Aravind Eye Hospital, Madurai, India, were southern Indians. tried to exclude most with prior ocular diseases associated loss...
Purpose . To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone. Methods Case reports. Results Bilateral shallow anterior chambers high intraocular pressure decline visual acuity were reported patients within days intake chlorthalidone for systemic hypertension. Gonioscopy confirmed appositional while choroidal detachment ciliochoroidal revealed on ultrasonographic studies....
Congenital glaucomas are present at birth while infantile refer to elevated ocular pressures and other sequelae with onset from up three years of life. Developmental associated developmental anomalies the eye birth. Defective primary development outflow structures causes whereas abnormalities secondarily affecting aqueous cause secondary (e.g. glaucoma persistent hyperplastic vitreous, spherophakia, retinopathy prematurity, Sturge Weber syndrome, congenital ectropion uveae, etc). This review...
Optical Coherence Tomography (OCT) imaging is pivotal in diagnosing ophthalmic conditions by providing detailed cross-sectional images of the anterior and posterior segments eye. Nonetheless, speckle noise other artifacts inherent to OCT impede accuracy diagnosis significantly. In this study, we proposed an enhanced denoising model using a Residual U-Net architecture that effectively diminishes improves image clarity across both Anterior Segment (ASOCT) polarization-sensitive (PSOCT) images....