- Corneal Surgery and Treatments
- Osteoarthritis Treatment and Mechanisms
- Streptococcal Infections and Treatments
- Knee injuries and reconstruction techniques
- Bacterial Identification and Susceptibility Testing
- Mesenchymal stem cell research
- Antimicrobial Resistance in Staphylococcus
Georgia Institute of Technology
2014-2023
The Wallace H. Coulter Department of Biomedical Engineering
2014-2023
University of Pittsburgh Medical Center
2021
Abstract Introduction Micronized dehydrated human amnion/chorion membrane (μ-dHACM) is derived from donated placentae and has anti-inflammatory, low immunogenic anti-fibrotic properties. The objective of this study was to quantitatively assess the efficacy μ-dHACM as a disease modifying intervention in rat model osteoarthritis (OA). It hypothesized that intra-articular injection would attenuate OA progression. Methods Lewis rats underwent medial meniscal transection (MMT) surgery induce OA....
Bloodstream infections caused by MSSA are associated with significant morbidity and mortality. Traditional treatment of bacteraemia includes an IV antistaphylococcal β-lactam surgical source control when indicated.To evaluate the time to blood culture clearance as well in-hospital 90 day mortality in patients persistent treated combination penicillin plus carbapenem therapy.Consecutive therapy were identified study investigators reviewed independent clinicians. The decision initiate was made...
Background: Micronized dehydrated human amnion/chorion membrane (mdHACM) has reduced short term post-traumatic osteoarthritis (PTOA) progression in rats when delivered 24 h after medial meniscal transection (MMT) and is being investigated for clinical use as a disease modifying therapy. Much remains to be assessed, including its potential longer-term therapeutic benefit treatment effects onset of joint degeneration. Objectives: Characterize acute with mdHACM determine whether administered...