A5039731213- Liver Disease Diagnosis and Treatment
- Heart Failure Treatment and Management
- Diet, Metabolism, and Disease
- Menopause: Health Impacts and Treatments
- Cancer Cells and Metastasis
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Pharmacogenetics and Drug Metabolism
- Estrogen and related hormone effects
- Cardiac pacing and defibrillation studies
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Retinal Diseases and Treatments
- Endometriosis Research and Treatment
- Urticaria and Related Conditions
- Metabolism and Genetic Disorders
- Endometrial and Cervical Cancer Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Orthopaedic implants and arthroplasty
- Diet and metabolism studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Medication Adherence and Compliance
- Dermatology and Skin Diseases
- Potassium and Related Disorders
Novartis (Italy)
2006-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
Centro di Riferimento Oncologico
2023-2024
Azienda Ospedaliera di Perugia
2023
Ospedale Buccheri la Ferla Fatebenefratelli
2023
Ospedale Santa Maria della Misericordia di Udine
2023
Ospedali Riuniti di Foggia
2023
Ospedale Civile di Venezia
2023
Evidence (Italy)
2023
Azienda Usl Toscana Centro
2019
Background. Migraine attacks are often treated with simple analgesics or ergotamme-containing preparations alone in combination anti-emetics. Although also sometimes used to treat migraine, nonsteroidal anti-inflammatory drugs (NSAIDs) have not been systematically evaluated controlled clinical trials, particularly comparison the newer drug sumatriptan. Sumatriptan is a specific migraine treatment which has recently become among most widely prescribed acute therapies. However, while...
Abstract Background Recent estimates indicate an increase in the prevalence of skin diseases children. Few large epidemiologic studies have examined trends Europe. This study evaluated incidence and frequently occurring pediatric ( PSD s) Italy as seen by family pediatricians FP s). Methods Data were retrospectively extracted from Pedianet database (2006–2012) children ages 0 to 14 years presenting with a disease at their . The calculated per year stratified according sex, age, geographic...
Insulin resistance is a significant risk factor for hepatic fibrosis in patients with both non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C (CHC), either directly or by favouring steatosis. Several methods are available to assess insulin resistance, but their impact on this issue has never been evaluated.To determine the relative contribution of steatosis, metabolic abnormalities measured different basal post-load parameters, CHC NAFLD patients.In 90 pair-matched NAFLD,...
Awareness about the importance of implementing
Factors predicting prescriptions of triple therapy were investigated in a large group general practitioners Italy. In the population treated by identified practitioners, cohort newly diagnosed chronic obstructive pulmonary disease patients was extracted from IMS Health Longitudinal Database during period 2010-2013. From diagnosis, 1-year follow-up evaluated. Thirty-two thousand forty-six evaluated (57.7% male, mean age 67 years). During 2 years prior to diagnosis less than 13% requested with...
Sacubitril/valsartan reduces heart failure (HF)-related hospitalizations and cardiovascular mortality in PARADIGM-HF has become a foundational treatment for HF with reduced ejection fraction (HFrEF). However, data of its routine real-world use are limited, evidence from Italian settings is lacking. The REAL.IT study aimed to characterize the demographics, pharmacotherapy, clinical characteristics outcomes sacubitril/valsartan-treated patients HFrEF. Electronic medical records initiating...
Seborrheic dermatitis (SD) is a common disorder for which no satisfactory curative treatment exists. Preliminary studies suggest that terbinafine may be effective. The efficacy and tolerability of oral was evaluated in multi-site SD randomized, double-blind, placebo-controlled study. For this purpose, 174 adult patients with lesions involving ≥3 skin areas, each causing ≥2 moderate/severe symptoms according to pre-defined clinical score, were classified the localization lesions:...
Introduction: GOLD guideline recommendations are currently the “gold standard” for treatment of COPD patients.Objectives: The objective this analysis was to evaluate compliance with guidelines in managing patients’ by general practitioners (GPs) and pulmonologists. Since inhaled corticosteroid (ICS) use is defined as inappropriate mild moderate patients, special attention paid ICS therapy these classes.Methods: study based on Italian GP database IMS Health Longitudinal Patient Database (IMS...
Objective To assess the efficacy of a continuous-combined transdermal patch (estradiol/ norethisterone acetate [E2/NETA] 25/125; Estragest TTS, Novartis, Basel, Switzerland) in reduction bone loss postmenopausal women. Design In 96-week, double-blind, randomized, multicenter, parallel study, 124 healthy women with an intact uterus more than 4 years after menopause received either E2/NETA (0.025/0.125 mg/day) or placebo for 24 treatment cycles; diet was normalized calcium intake. Lumbar spine...
Abstract Aims The current European Society of Cardiology (ESC) guidelines provide clear indications for the treatment acute and chronic heart failure (HF). Nevertheless, there is a constant need real‐world evidence regarding effectiveness, adherence, persistence drug therapy. We investigated use sacubitril/valsartan HF with reduced ejection fraction in clinical practice Italy. Methods results An observational, retrospective, non‐interventional cohort study based on electronic medical records...
Identification of clinical factors that can predict mortality and hospital early readmission in acute decompensated heart failure (ADHF) patients help emergency department (ED) physician optimize the care-path resource utilization. We conducted a retrospective observational study 530 ADHF evaluated ED an Italian academic 2013. Median age was 82 years, females were 55%; 31.1% discharged directly from (12.5% after short staying observation unit), while 68.9% admitted to ward (58.3% 10.6%...
Objective The aim of this analysis is to find any association between the use hormone replacement therapy (HRT) and sociodemographic clinical factors among women attending 54 menopause clinics in Italy.Methods includes data relating 17 851 who attended one Italy for general gynecological evaluations counselling 1995 1997. characteristics reporting ever HRT were compared with those never users. odds ratios (ORs) computed relation selected reference categories, together their 95% confidence...
Objective To assess the overall effectiveness of anti-vascular endothelial growth factor (VEGF) therapy in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) a clinical practice setting. Study design EAGLE was retrospective, 2-year, cohort observational, multicenter study conducted Italy that analyzed secondary data nAMD. The primary endpoint evaluated mean annualized number anti-VEGF injections at Years 1 and 2. main endpoints change visual acuity (VA) from...
Importance To date, the clinical benefit and utility of implementing a DPYD/UGT1A1 pharmacogenetic-informed therapy with fluoropyrimidines and/or irinotecan have not been prospectively investigated. Objective examine clinically relevant toxic effects, hospitalizations, related costs while preserving treatment intensity efficacy outcomes in patients gastrointestinal cancer. Design, Setting, Participants This nonprespecified secondary analysis stems from Pre-Emptive Pharmacogenomic Testing for...