A5101954694- Organic Electronics and Photovoltaics
- Kruppel-like factors research
- Eicosanoids and Hypertension Pharmacology
- Cancer-related molecular mechanisms research
- Conducting polymers and applications
- Genomics, phytochemicals, and oxidative stress
- Ginseng Biological Effects and Applications
- Lipid metabolism and disorders
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Circular RNAs in diseases
- Metabolism, Diabetes, and Cancer
- Bioactive Compounds and Antitumor Agents
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Cancer Cells and Metastasis
- Mycobacterium research and diagnosis
- Terahertz technology and applications
- Liver physiology and pathology
- Peroxisome Proliferator-Activated Receptors
- Phytochemistry and biological activity of medicinal plants
- Ovarian function and disorders
- MicroRNA in disease regulation
- Reproductive Biology and Fertility
- Esophageal Cancer Research and Treatment
Shandong University
2004-2025
Shandong Provincial Hospital
2012-2021
Shandong First Medical University
2019-2021
Shandong Tumor Hospital
2019
Abstract Obtaining controllable active layer morphology plays a significant role in boosting the device performance of organic solar cells (OSCs). Herein, quaternary strategy, which incorporates polymer donor D18‐Cl and small molecule acceptor AITC into host D18:N3, is employed to precisely modulate crystallization kinetics for favorable evolution within layer. In situ spectroscopic measurements during film‐formation demonstrate that while works as nucleator promote aggregation D18 foster...
Grape seed proanthocyanidin extracts (GSPE) belonging to polyphenols, possess various biological effects including anti-inflammation, anti-oxidant, anti-aging, anti-atherosclerosis, etc. GSPE is potential in regulating endothelial function. However, the underlying mechanism not clear yet. In this study, by small interfering RNA (siRNA) knocking down, we proved that increase nitric oxide synthase (eNOS) expression human umbilical vessel cells (HUVECs) vitro, which was attributed its...
Abstract Long noncoding RNA (lncRNA) LINC‐PINT expression is inhibited in many types of cancer cells, suggesting its role as a tumor suppressor. However, the functionality gastric and clinical values are unknown. In present study, we found that lncRNA was downregulated, while microRNA‐21 ( miR‐21 ) upregulated tissues than adjacent healthy patients. A significant inverse correlation between levels both tissues. The low level high were correlated with poor prognosis. overexpression casued...
Germacrone is one of the natural bioactive compounds found in Rhizoma curcuma essential oils. In this study, potential anti-cancer effect germacrone gastric cancer cell line BGC823 was investigated.The viability and proliferative activity were assessed, cycle analysis also performed. Hoechst 33258 Annexin V/PI double staining used for detection apoptosis. Protein profiles cycle-related apoptosis-related proteins assessed.MTT assay revealed that had marked cytotoxicity on cells. induced...
Abstract Achieving commercial viability for organic solar cells (OSCs) requires non‐toxic, non‐halogenated solvent processing. However, poor solubility and suboptimal morphology of commonly used active layer materials have been limiting their applications high‐performance OSCs. This study introduces a novel random terpolymer, PM7‐TTz50, designed to overcome these challenges. By incorporating 50 mol% co‐planar thiophene‐thiazolothiazole (TTz) unit into the PM7 backbones, resulting terpolymer...
ABSTRACT We investigated whether low-dose phloretin served as daily dietary supplements could ameliorate diabetic atherosclerosis and the role of kruppel-like factor 2 (KLF2). HUVECs cultured in high glucose medium were treated with different concentrations KLF2 mRNA, protein level was detected. Diabetes induced using streptozotocin Apoe−/- mice after which they fed a high-cholesterol diet for 8 weeks. Diabetic injected shRNA-lentivirus or control virus 20 mg/kg phloretin. Glucose, lipid...
The aim of the present study was to evaluate influence tumor necrosis factor-alpha (TNF-α) -308 G > A polymorphism on hepatocellular carcinoma (HCC) risk.The case-control conducted in a Han Chinese population consisting 753 HCC patients and 760 controls from May 2010 March 2013. TNF-a promoter polymorphisms were detected. Conditional logistic regression performed analyze association between TNF-α risk HCC, which estimated by odds ratios (ORs) their 95% confidence intervals (95% CIs).The...
Background The aim of this study was to evaluate the association between CYP2A13 polymorphisms and lung cancer susceptibility using HapMap database. Methods A case‐control analysis 532 subjects with 614 controls no personal history disease performed. tag SNPs rs1645690 rs8192789 for were selected, genetic confirmed experimentally through real‐time PCR, cloning, sequencing assay. Results SNP frequency in consistent Project database Han‐Chinese risk associated non‐smokers. shares a 93.5%...
Aim. To investigate the effect of Tongxinluo (Txl), a Chinese herbal compound, on diabetic peripheral neuropathy (DPN). Methods and Results. Diabetic rat model was established by peritoneal injection streptozotocin (STZ). Txl ultrafine powder treatment for 16 weeks from baseline significantly reversed impairment motor nerve conductive velocity (MNCV), mechanical hyperalgesia, structure. We further proved that upregulates PGC-1α its downstream factors including COX IV SOD, which were involved...
Objective: To investigate the effects of desmopressin acetate and pituitrin on proliferation, contraction, secretion hepatic stellate cells (HSCs). Methods: The human HSC cell line LX-2 was selected as research model. And three groups were designed: blank control group, group (three subgroups: 1×10-10mol/L, 1×10-9mol/L, 1×10-8mol/L acetate), 0.1 U/L, 1.0 10.0 U/L pituitrin). Water-soluble tetrazolium salt (WST)-1 assay used to evaluate proliferation; collagen gel contraction assess...