A5038060846- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Intensive Care Unit Cognitive Disorders
- Public Health and Nutrition
- Hemodynamic Monitoring and Therapy
- Family and Patient Care in Intensive Care Units
- Kawasaki Disease and Coronary Complications
- Mosquito-borne diseases and control
- Healthcare Quality and Satisfaction
- Pneumonia and Respiratory Infections
- COVID-19 Prevention and Impact
- Blood transfusion and management
- COVID-19 and Mental Health
- Andrographolide Research and Applications
- Neonatal and Maternal Infections
- SARS-CoV-2 and COVID-19 Research
- Pediatric Pain Management Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Diverse Scientific Research Studies
- Infectious Encephalopathies and Encephalitis
- COVID-19 Impact on Reproduction
- Infant Development and Preterm Care
RSUD Prof. Dr. Saiful Anwar Malang
2014-2024
KK Women's and Children's Hospital
2024
China Medical University
2024
University of Brawijaya
2013-2023
University of Oxford
2021
Prince Charles Hospital
2021
Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income (LMICs). We sought investigate differences in clinical outcomes and identify factors contributing disparity countries. Methods International Severe Acute Respiratory Emerging Infections Consortium (ISARIC) database was queried include children under 19 years age admitted hospital from January 2020 April 2021 with suspected or confirmed...
Mortality from pneumonia is three times higher in Asia compared with industrialized countries. We aimed to determine the epidemiology, microbiology, and outcome of severe PICUs across Pediatric Acute Critical Care Medicine Asian Network (PACCMAN).
Indonesia's national response to COVID-19 evolved rapidly throughout 2020. Understanding pandemic and outcomes is crucial for better mitigation strategies ahead. This study describes the characteristics of patients admitted ICU during early stages pandemic.This a multi-centre prospective observational including from twelve collaborating hospitals in Indonesia. All were clinically suspected or laboratory-confirmed cases between January 2020 March 2021. The primary outcome was monthly...
Background: Fluid resuscitation is the mainstay of treatment to counteract massive plasma leakage in dengue shock syndrome. We aimed determine differences clinical outcomes and hemodynamic parameters children with syndrome post restrictive liberal fluid resuscitation. Materials Methods: A retrospective observational study pediatric patients who were between one month 18 years old, presented criteria for hemorrhagic fever (DHF) grade III IV based on WHO classification 2011, admitted Saiful...
We describe a child with acute fever and abdominal pain who developed rash edema of extremities. Blood test revealed thrombocytopenia, lymphopenia, positive dengue-IgM, hypoalbuminemia elevated procalcitonin. Right pleural effusion from chest x-ray. Diagnosed as dengue hemorrhagic (DHF) grade 1, however, at 7th day illness, altered mental status, respiratory circulatory failure occurred. Laboratory examination showed marked transaminitis, metabolic acidosis, D-dimer, decrease fibrinogen,...
Introduction: Elizabethkingia meningoseptica is a Gram-negative Bacillus associated with various nosocomial infections. These bacteria cause meningitis, sepsis, bacteremia, pneumonia, infections of the skin and soft tissue, ocular infections, sinusitis, epididymitis, endocarditis. They can be opportunistic pathogens in newborns immunocompromised patients. Case Presentation: The current study reported case bacteremia caused by E. an infant presented clinical presentations suggestive...
Background: Fluid therapy for dengue shock syndrome (DSS) requires a dynamic approach that involves monitoring of the pathophysiological processes as well preload, contractility, and afterload assessment during course infection. Hemodynamically unstable DSS patients received in referral setting often complicated by fluid overload secondary Objective: This study aims to provide hemodynamic profiles responsiveness pediatric admitted PICU with DSS. Methods: Hemodynamic profiles, laboratories,...
Children admitted in the pediatric intensive care unit (PICU) often deal with long-term morbidities affecting physical, cognitive, emotional, social, and psychiatric symptoms. We aimed to identify internal external factors which predict occurrence of neurocognitive psychological disorders survivors at 3 months after PICU discharge.
Background. Coronavirus disease 2019 (Covid-19) is infrequently associated with severe complications in children. A recent observation has linked Covid-19 to recurrent ventricular fibrillation pediatric patients. Case report. We present a distinct case of an 11-year-old male child who was previously healthy but obese. The patient experienced as complication and underwent multiple defibrillation shocks, ultimately surviving the ordeal. Early on management refractory fibrillation, administered...
Latar belakang. Asma merupakan penyakit saluran napas akibat adanya peradangan kronis pada yang sering terjadi anak-anak dengan prevalensi mencapai 20%. Steroid anti-inflamasi dinilai paling efektif dalam terapi seperti asma. Akan tetapi, penelitian sebelumnya mengungkapkan bahwa steroid memiliki potensi menyebabkan penurunan kepadatan massa tulang atau osteoporosis. Tujuan. Penelitian ini bertujuan untuk menganalisis hubungan pemakaian inhalasi osteoporosis pasien asma anak. Metode. Studi...
Tata laksana adekuat sepsis dapat memperbaiki luaran pasien. Surviving campaign (SSC) guidelines 2012 merupakan panduan internasional tata berat dan syok septik, namun implementasinya dipengaruhi oleh sumberdaya fasilitas kesehatan. Penelitian ini mengevaluasi implementasi SSC di rumah sakit. Studi prospektif dilakukan antara Februari-Juni 2013 pada seluruh pasien usia 1 bulan–18 tahun yang memenuhi kriteria sepsis, dengan menilai penggunaan cairan resusitasi obat vasoaktif, waktu...
Decrease of lymphocyte  apoptosis is one factor that leads to chronic airway inflammation in allergic asthma. Previous studies revealed the role interleukin (IL)-4 preventing apoptosis; however there are few about lymphocyte-Bax and its relationship with IL-4 asthma. The aim study to demonstrate via inactivation bronchioli and lungs asthmatic mice. It a randomized control group experimental . subject was Balb/c mice that categorized into 2 groups: asthma non-asthma. Asthma sensitized...
Background: Coronavirus Disease-2019 (COVID-19) in children tend to have milder clinical manifestation. However, some develop critical conditions and require mechanical ventilation the Pediatric Intensive Care Unit (PICU). Various modalities are recommended for ventilation, such as High Flow Nasal Cannula (HFNC), Continuous Positive Airway Pressure (CPAP), or invasive with intubation. This study aims describe feature, usage, outcome of COVID-19.
 Methods: is a retrospective COVID-19...
Prior studies have shown that septic shock survivors had a normal cardiac index (CI) and systemic vascular resistance (SVRI). However, this feature seems to be questionable in other-caused shock, since several factors are associated with the hemodynamic profile. This study aims describe profiles (preload, inotropy, afterload, stroke volume, output) after fluid resuscitation vasoactive therapy children shock.Children aged 1 month 18 years old conditions were included study. Fluid was...
Generally, children infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS COV-2) have mild symptoms or are asymptomatic. However, some severe and critical affecting several organ systems, including the gastrointestinal, cardiovascular, respiratory, neurological systems. These associated multisystem inflammatory syndrome in (MISC). This study aimed to describe clinical features, ventilation modalities usage, outcome conditions of these children. was a retrospective COVID-19 MISC...
Critically ill children with anemia often requires blood transfusion, which can cause several complications. It is important to decide when start the red cell (RBC) transfusion; however, guidelines still lacking. The aim of this study was compare restrictive and liberal transfusion strategy.This an observational retrospective critically-ill who receive RBC transfusion. Subjects categorized into two groups by initial hemoglobin (Hb), that is, (Hb ≤ 7 g/dl) 9.5 strategy. In each group,...
Introduction: Severe pneumonia is a common indication for admission to the pediatric intensive care unit (PICU) and leading cause of morbidity mortality. The lack epidemiology outcome data from Asia barrier improving outcomes severe in region. Methods: This prospective multicenter cohort study carried out April 2019 2022. Fifteen PICUs participated this under Pediatric Acute & Critical Care Medicine Asian Network. Epidemiological, microbiological were collected up hospital discharge....
The failure of lymphocyte apoptosis is one the factors causing chronic airway inflammation in asthma. Some studies indicate role Bcl-2 inhibition apoptosis, but still little research on Bax and its relationship to purpose this study was prove Bcl-2-lymphocyte decrease Bax-lymphocytes bronchiolus lung asthmatic mice. This a randomized control group design. Subjects were Balb/c mice which divided into 2 groups: non-asthma Asthma sensitized with ovalbumin intraperitoneally day 0 14, followed by...
Background Sepsis is a major cause of morbidity and mortality in children. The American College Critical Care Medicine (ACCM) protocol currently use the management septic shock carries risk fluid overload. With ultrasonographic monitoring, Ultrasound-guided Fluid Resuscitation (USFR) may reduce incidence overload mortality.
 Objective To assess difference outcomes resuscitation pediatric using USFR vs. ACCM protocols.
 Methods This randomized clinical trial involved 36 subjects...
Background Early recognition of septic shock in terms clinical, macrocirculatory hemodynamic, and microcirculatory laboratory parameters is a fundamental challenge the emergency room intensive care unit for early identification, adequate management, prevention disease progression, reduction mortality risk.
 Objective To evaluate possible correlations between survival outcomes post-resuscitation pediatric patients clinical signs, hemodynamics, as well findings.
 Methods This...
Background Procalcitonin (PCT) level is one of known biomarker in septic diagnosis, but limited studies report its benefit predicting the outcomes children with sepsis. Neutrophil to lymphocyte (NLR) and mean platelet volume (MPV) are simple biomarkers inflammation that can be measured routine hematological examination which role organ dysfunction remain unclear.
 Objective To understand correlations between PCT level, NLR, MPV, tested first day admission intensive care unit.
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Background: The parenting style is chosen to educate children so that they have a mindset and behavior are in line with community standards. Mothers an important role educating nurturing according their stage of development. Today, many mothers dual roles as caregivers workers. This will certainly affect development because the limited interaction between mother child. Objective: study aims prove whether ability socially adjust cognitive relationship used by working for aged four five years...
During the Covid-19 outbreak, Ministry of Women's Empowerment and Child Protection recorded SYMPHONY PPA data 3,087 cases child abuse, namely 852 physical violence, 768 psychological cases, 1,848 sexual as January 1 - June 19 2020. Emotional intelligence should be developed strengthened since age is closely related to moral, social, personal, further development for better. The research objective was determine relationship between parental education well family social interaction on...