Background: The Theory of Planned Behavior (TPB) and the Health Belief Model (HBM) were used to examine opinion behaviors older adults regarding Coronavirus Disease 2019 (COVID-19), social distancing practices, stay-at-home orders, hypothetical public policy messaging strategies. Method: A convenience sample ( N = 242) 60 in state Maryland took part an online survey. Respondents filled out questions demographic information, political affiliation, current behaviors, TPB HBM constructs our...

Abstract Objectives: A growing body of research suggests that regular participation in long-term exercise is associated with enhanced cognitive function. However, less known about the beneficial effects acute on semantic memory. This study investigated brain activation during a memory task after single session healthy older adults using functional magnetic resonance imaging (fMRI). Methods: Using within-subjects counterbalanced design, 26 participants (ages, 55–85 years) underwent two...

Background: The purpose of this study was to examine the impact antecedent variables on older adults’ intention get a CORONAVIRUS DISEASE-2019 vaccine. Older adults are at higher risk severe illness from disease and face an increasingly ageist general population who misrepresent pandemic as adult problem. We use Theory Planned Behavior framework vaccine behavior intention. Method: A convenience sample ( n = 583) aged 60 in United States participated online survey using vignettes....

Background: Exercise training (ET) has neuroprotective effects in the hippocampus, a key brain region for memory that is vulnerable to age-related dysfunction. Objective: We investigated of ET on functional connectivity (FC) hippocampus older adults with mild cognitive impairment (MCI) and cognitively normal (CN) control group. also assessed whether ET-induced changes hippocampal FC (Δhippocampal-FC) are associated task performance (Δmemory performance). Methods: 32 (77.0±7.6 years; 16 MCI...

Abstract Aging is associated with disruptions in circadian rhythms, lower brain white matter integrity, and cognitive changes. However, whether integrity serves as a potential mechanism linking dysfunction to age-related abilities older adults unclear. We investigated cross-sectional associations of actigraphic rest/activity rhythms (RARs) whole-brain tract fractional anisotropy (FA) executive function performance 156 without dementia from the BIOCARD study (mean age = 71.3 years, including...

Although both exercise and sleep are significant lifestyle factors in cognitive aging, the interaction of these two with respect to cognition remains be determined.Also, little is known regarding role basal ganglia (BG) aging despite its involvement executive function.The primary objective this study was investigate between acute on function performance, secondarily, assess if BG volume mediates interaction.Thirty healthy older adults (65.8 ± 7.3 years) completed 30 minutes seated rest or...

Greater physical activity and better sleep are associated with reduced risk of cognitive decline dementia among older adults, but little is known about their combined associations measures brain function neuropathology. This study investigated potential independent interactive cross-sectional relationships between actigraphy-estimated total volume (TVPA) patterns [i.e., time (TST), efficiency (SE)] resting-state functional magnetic resonance imaging (rs-fMRI) large scale network connectivity...

Brain injury is the main cause of mortality and morbidity after cardiac arrest (CA). Changes in cerebral blood flow (CBF) reperfusion are associated with brain recovery. To characterize relative CBF (rCBF) CA, 14 rats underwent 7 min asphyxia-CA were randomly treated 6 h post-resuscitation normothermic (36.5–37.5℃) or hypothermic- (32–34℃) targeted temperature management (TTM) (N = 7). rCBF was monitored by a laser speckle contrast imaging (LSCI) technique. recovery evaluated neurologic...

Individuals with Mild Cognitive Impairment (MCI) are at an elevated risk of dementia and exhibit deficits in cognition cortical gray matter (GM) volume, thickness, microstructure. Meanwhile, exercise training appears to preserve brain function macrostructure may help delay or prevent the onset individuals MCI. Yet, our understanding neurophysiological effects MCI remains limited. Recent work suggests that measures microstructure using diffusion imaging be sensitive early cognitive changes...

Abstract Objectives: Ample evidence suggests exercise is beneficial for hippocampal function. Furthermore, a single session of aerobic provides immediate benefits to mnemonic discrimination performance, highly hippocampal-specific memory process, in healthy younger adults. However, it unknown if alters older adults, who generally exhibit greater deterioration and deficits performance. Methods: We conducted within subject acute study 30 cognitively physically active adults underwent baseline...

Abstract Aging is associated with deterioration in dentate gyrus (DG) and CA3, both crucial hippocampal subfields for age susceptible memory processes such as mnemonic discrimination (MD). Meanwhile, a single aerobic exercise session alters DG/CA3 function neural activity rats younger adults can elicit short‐term microstructural alterations the hippocampus of older adults. However, our understanding effects acute on subfield integrity via microstructure limited. Thus, within subject‐design...

The hippocampus experiences structural and functional decline with age is a critical region for memory many cognitive processes. Exercise beneficial the aging brain shows preferential benefits hippocampal volume, activation, memory-related However, research thus far has primarily focused on effects of exercise long-term volumetric changes in using magnetic resonance imaging. Critically, microstructural alterations within over short time intervals are associated neuroplasticity that do not...

The hippocampus is a brain structure known to be important for memory. However, studies examining relations between hippocampal volume and memory across development yield mixed results. This may due in part the fact that coarser measure of composition. Studies have begun examine measures diffusion, which capture characteristics microstructure hippocampus, thus provide additional information about integrity underlying neural circuits. present study applied this approach developmental period...

Abstract The relationship between gait speed and working memory is well-understood in older adults. However, it remains to be determined whether this also exists younger adults; there little known regarding the possible neural mechanism underlying association memory. aims of study are determine if is: (1) an performance; (2) a mediating role cerebellar subregion volume correlation healthy 1054 adults (28.7 ± 3.6 years) from Human Connectome Project were included analyses. A four-meter test...

Objectives: Psychosocial stressors associated with the COVID-19 pandemic may increase risk of depression and anxiety in general population. Individuals approaching or within older adulthood be especially vulnerable to these psychosocial their impact on mental health outcomes. Consequently, there is an urgent need identify protective factors for adults. The purpose present study was determine relative contribution coping flexibility (CF) two distinct strategies, forward-focused...

The well-elucidated improvement of mood immediately after exercise in older adults presumably involves adaptations emotion-processing brain networks. However, little is known about effects acute on appetitive and aversive emotion-related network recruitment adults. purpose this study was to determine the effect exercise, compared a seated rest control condition, pleasant unpleasant regional activation healthy Functional MRI data were acquired from 32 active during blocked presentations...