Håkon Olav Leira

ORCID: 0000-0003-0845-3891
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Radiotherapy Techniques
  • Tracheal and airway disorders
  • Augmented Reality Applications
  • Surgical Simulation and Training
  • Soft Robotics and Applications
  • Salivary Gland Tumors Diagnosis and Treatment
  • Robotics and Sensor-Based Localization
  • Flow Measurement and Analysis
  • Occupational exposure and asthma
  • Voice and Speech Disorders
  • Medical Imaging Techniques and Applications
  • Head and Neck Cancer Studies
  • Air Quality Monitoring and Forecasting
  • AI in cancer detection
  • Ultrasound in Clinical Applications
  • Advanced Image and Video Retrieval Techniques
  • Inhalation and Respiratory Drug Delivery
  • Global Cancer Incidence and Screening
  • Esophageal Cancer Research and Treatment
  • Occupational Health and Safety Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Head and Neck Surgical Oncology
  • Chemotherapy-related skin toxicity

Norwegian University of Science and Technology
2014-2025

St Olav's University Hospital
2014-2025

Introduction Our motivation is increased bronchoscopic diagnostic yield and optimized preparation, for navigated bronchoscopy. In bronchoscopy, virtual 3D airway visualization often used to guide a tool peripheral lesions, synchronized with the real time video Visualization during segmentation methods, differs. Time consumption logistics are two essential aspects that need be when integrating such technologies in interventional room. We compared three different approaches obtain centerlines...

10.1371/journal.pone.0144282 article EN cc-by PLoS ONE 2015-12-11

Endobronchial ultrasound (EBUS) is used in the minimally invasive sampling of thoracic lymph nodes. In lung cancer staging, accurate assessment mediastinal structures essential but challenged by variations anatomy, image quality, and operator-dependent interpretation. This study aimed to automatically detect segment nodes blood vessels employing a novel U-Net architecture-based approach EBUS images. A total 1161 images from 40 patients were annotated. For training validation, 882 30 145 5...

10.3390/jimaging10080190 article EN cc-by Journal of Imaging 2024-08-06

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a cornerstone in minimally invasive thoracic lymph node sampling. In lung cancer staging, precise assessment of position crucial for clinical decision-making. This study aimed to demonstrate new deep learning method classify nodes based on their anatomical location using EBUS images. Bronchoscopists labeled stations real-time according the Mountain Dressler nomenclature. images were then used train and test...

10.3390/jimaging11010010 article EN cc-by Journal of Imaging 2025-01-05

Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) of mediastinal lymph nodes is essential for lung cancer staging and distinction between curative palliative treatment. Precise sampling crucial. Navigation multimodal imaging may improve the efficiency EBUS-TBNA. We demonstrate a novel EBUS-TBNA navigation system in dedicated airway phantom.Using convex probe EBUS bronchoscope (CP-EBUS) with an integrated sensor electromagnetic (EM) position tracking, we performed...

10.1007/s11548-015-1326-7 article EN cc-by International Journal of Computer Assisted Radiology and Surgery 2015-11-28

The accuracy of navigated bronchoscopy relies on a best possible correlation between the preoperative computed tomography images used for planning and actual tumor position during bronchoscopy. Change in lung structure procedure may reduce success rate. size changes breathing, which be predicted at least partly compensated by navigation system. We have studied effect itself, to see if how causes further distortions, might harder predict compensate.Using newly developed tracking sensors, we...

10.1097/lbr.0b013e31829cb2b5 article EN Journal of Bronchology & Interventional Pulmonology 2013-07-01

Purpose: The authors have studied the accuracy and robustness of a prototype electromagnetic window field generator (WFG) in an interventional radiology suite with robotic C-arm. overall purpose is development guidance systems combining real-time imaging tracking flexible instruments for bronchoscopy, laparoscopic ultrasound, endoluminal surgery, endovascular therapy, spinal surgery. Methods: WFG has torus shape, which facilitates x-ray through its centre. compared performance to that...

10.1118/1.3666768 article EN Medical Physics 2011-12-23

Purpose: Electromagnetic based navigated bronchoscopy using preoperative CT images has reached the clinic during last decade. One of challenges is “CT to patient anatomy alignment” acquired days or even weeks ahead bronchoscopy. An automatic registration method, without manual anatomical landmarks, was developed, implemented, and evaluated in current study. Methods: The method aligns automatically patientˈs initial part algorithm a modified version an iterative closest point algorithm, which...

10.1118/1.4866884 article EN Medical Physics 2014-03-07

Background and purpose: Multi-disciplinary Team (MDT) meetings are widely regarded as the ‘gold standard’ of lung cancer care. MDTs improve adherence to clinical guidelines for patients. In this study, we describe compare in Denmark Norway by combining national surveys MDT-Metric Observation Decision-making (MDT-MODe) instrument. Materials method: Identical were sent out all MDT centers Danish Lung Cancer Group Norwegian Group. Six centers, three Norway, observed using MDT-MODe Results...

10.2340/1651-226x.2024.40777 article EN cc-by Acta Oncologica 2024-08-11

Background Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is the endoscopic method of choice for confirming lung cancer metastasis to mediastinal lymph nodes. Precision crucial correct staging and clinical decision-making. Navigation multimodal imaging can potentially improve EBUS-TBNA efficiency. Aims To demonstrate feasibility a image guiding system using electromagnetic navigation bronchoschopy in humans. Methods Four patients referred diagnosis with were enrolled...

10.1371/journal.pone.0171841 article EN cc-by PLoS ONE 2017-02-09

One of the major challenges in electromagnetic navigated bronchoscopy is navigation accuracy. An initial rigid image-to-patient registration may not be optimal for entire lung volume, as tissue anatomy likely to have shifted since time computer tomography (CT) acquisition. The accuracy will also affected throughout procedure by breathing, coughing, patient movement and displacements due pressure from tools. A method minimize negative impact these factors updating locally during needed...

10.1002/mp.12361 article EN Medical Physics 2017-05-25

Electromagnetic guided bronchoscopy is a new field of research, essential for the development advanced investigation airways and lung tissue. Consecutive problem-based solutions refinements are urgent requisites to achieve improvements. For that purpose, our intention build complete research platform electromagnetic bronchoscopy. The experimental interventional tracking system in conjunction with C-arm cone beam CT unit presented this paper. animal model navigation performed well aims were...

10.3109/13645706.2010.518747 article EN Minimally Invasive Therapy & Allied Technologies 2010-09-27

The purpose of this study was to evaluate the accuracy a method for estimating tip position fiber optic shape-sensing (FOSS) integrated instrument being inserted through bronchoscope. A modified guidewire with multicore optical into working channel custom-made catheter three electromagnetic (EM) sensors. displacement between instruments manually set, and point-based applied match EM sensors corresponding points on shape. evaluated in realistic bronchial model. An additional sensor used...

10.1016/j.medengphy.2024.104116 article EN cc-by Medical Engineering & Physics 2024-02-14

Abstract Introduction Endobronchial ultrasound with transbronchial needle aspiration (EBUS‐TBNA) has become an important diagnostic tool for the pulmonologist. Learning this procedure and maintaining technical skills requires continuous practice evaluation. Objectives The aims of study were a retrospective evaluation quality EBUS‐technique learning profile endoscopy team during first years (2007–2013) experience in unselected population. Methods EBUS‐TBNA procedures analysed clinical data,...

10.1111/crj.12475 article EN The Clinical Respiratory Journal 2016-03-09

To improve the prognosis of patients suffering from pulmonary diseases, such as lung cancer, early diagnosis and treatment are crucial. The analysis CT images is invaluable for diagnosis, whereas high quality segmentation airway tree required intervention planning live guidance during bronchoscopy. Recently, Multi-domain Airway Tree Modeling (ATM'22) challenge released a large dataset, both enabling training deep-learning based models bringing substantial improvement state-of-the-art task....

10.48550/arxiv.2311.01138 preprint EN cc-by arXiv (Cornell University) 2023-01-01

In flexible endoscopy techniques, such as bronchoscopy, there is often a challenge visualizing the path from start to target based on preoperative data and accessing these during procedure. An example of this only inside central airways in bronchoscopy. Virtual bronchoscopy (VB) does not meet pulmonologist's need detect, define sample frequent targets outside bronchial wall. Our aim was develop study new visualization technique for navigated bronchoscopy.We extracted shortest possible top...

10.1080/13645706.2017.1327870 article EN Minimally Invasive Therapy & Allied Technologies 2017-05-30

Knowledge about lung movement in health and disease is sparse. Current evaluation methods, such as CT, MRI external view have significant limitations. To study respiratory for image guided tumour diagnostics physiology, we needed a method that overcomes these We fitted balloon catheters with electromagnetic sensors, placed them lobes of ventilated pigs. The sensors sensed their position at 40 Hz an tracking field precision ∼0.5 mm. was evaluated by recording sensor different body positions...

10.1088/0031-9155/57/4/1071 article EN Physics in Medicine and Biology 2012-02-01

Objectives: The goal was to demonstrate the utility of open-source tracking and visualisation tools in targeting lung cancer.Material methods: study demonstrates first deployment Anser electromagnetic (EM) system with CustusX image-guided interventional research platform navigate using an endobronchial catheter injected tumour targets. Live animal investigations validated peripheral models innovative marking routine.Results: Novel model successfully achieved at all eight target sites across...

10.1080/13645706.2018.1544911 article EN Minimally Invasive Therapy & Allied Technologies 2018-11-15

10.1111/j.1755-3768.1961.tb00292.x article EN Acta Ophthalmologica 1961-08-01

Current image guidance systems for bronchoscopy are limited to the diagnosis of small tumors and placing fiducials radiation therapy surgery. Ideally, a navigation system should be useable range bronchoscopic procedures, including with concurrent radiology imaging control. As most rely on electromagnetic (EM) fields, it is advised leave C-arm mounted fluoroscopy unit outside operating field during navigation. We have assessed accuracy our research platform, containing an EM generator unit....

10.1097/lbr.0b013e318235d471 article EN Journal of Bronchology & Interventional Pulmonology 2011-10-01

Purpose The aim of this paper is to show how a specialized planning and guidance application called Fraxinus, can be built on top the CustusX platform (www.custusx.org), which an open source image-guided intervention software platform. Fraxinus has been customized meet clinical needs in navigated bronchoscopy. Methods requirements for were defined close collaboration between research scientists, developers clinicians (pulmonologists), CustusX. Its superbuild system downloads specific...

10.1371/journal.pone.0211772 article EN cc-by PLoS ONE 2019-02-08
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