A5060730567- Metal complexes synthesis and properties
- Organometallic Compounds Synthesis and Characterization
- Asthma and respiratory diseases
- Porphyrin and Phthalocyanine Chemistry
- IL-33, ST2, and ILC Pathways
- Food Allergy and Anaphylaxis Research
- Metabolomics and Mass Spectrometry Studies
- Metal-Catalyzed Oxygenation Mechanisms
- Dermatology and Skin Diseases
- Crystal structures of chemical compounds
- Respiratory viral infections research
- Nonlinear Optical Materials Research
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Vanadium and Halogenation Chemistry
- Metabolism and Genetic Disorders
- Allergic Rhinitis and Sensitization
- Oxidative Organic Chemistry Reactions
- RNA and protein synthesis mechanisms
- Immunodeficiency and Autoimmune Disorders
- Pediatric health and respiratory diseases
- Eosinophilic Esophagitis
- Polyoxometalates: Synthesis and Applications
McMaster University
2019-2023
Sohag University
2018-2022
University of Alberta
2016
Three new Cu (II), Pd (II) and Ag (I) complexes of bidentate Schiff base ligand 2‐[(4‐chlorobenzylidene)amino] phenol (HL) were synthesized. The stoichiometric ratios physicochemical properties these determined using elemental analyses, magnetic measurements, infrared UV–visible spectra, molar conductivity measurements thermal analyses. results revealed that the metal ions coordinated with through azomethine nitrogen phenolic oxygen atoms. AgL PdL are present in a 1:1 ratio square planar...
STAT6 (signal transducer and activator of transcription 6) is a factor that plays central role in the pathophysiology allergic inflammation. We have identified 16 patients from 10 families spanning three continents with profound phenotype early-life onset immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia esosinophilic gastrointestinal disease, asthma, elevated serum IgE, IgE-mediated food allergies, anaphylaxis. The cases were either sporadic (seven...
Herein, we report facile procedures for synthesis of a new Schiff base ligand (H2L,5-Diethylamino-2-({2-[(2-hydroxy-benzylidene)-amino]-phenylimino}-methyl)-phenol) and its Ag(I), Pd(II) Cu(II) complexes. The structure the H2L as well metal complexes was deduced based on wide range analytical, structural spectroscopic tools, along with theoretical evidence via density functional theory (DFT) calculations. obtained results indicated that (H2L) acts tetradentate N2O2 donor two azomethine...
The new Schiff base ligand 2,2′-{(4-chloro-1,2-phenylene)bis(nitrilo(E)methylylidene)}bis(4-bromophenol) (H2L) and its VO(II), Zn(II) ZrO(II) metal chelates have been synthesized characterized by spectral, powder x-ray diffraction (PXRD), molar conductance, magnetic measurements, thermal elemental analyses. molecular geometry of the prepared compounds has confirmed applying theoretical density functional theory calculations (DFT). analytical data showed that parent azomethine H2L binds to...
Sensitization to common environmental aeroallergens plays a significant role in the pathogenesis and severity of respiratory allergic disorders, specifically asthma rhinitis. Understanding sensitization patterns helps clinicians tailor care more effectively. This study examines subjects suspected having an disease Edmonton catchment area.Retrospective chart review skin prick test (SPT) results 11 performed between January 1st June 30th 2014 at University-based clinic, where patients are...
A1 Role of fibrocytes in allergic rhinitis Marie-Ève Côté, Boulay, Sophie Plante, Jamila Chakir, Louis-Philippe Boulet A2 Patterns aeroallergens sensitization Northern Alberta Hanan Ahmed, Maria-Beatriz Ospina, Kyriaki Sideri, Harissios Vliagoftis A3 Addressing acceptable risk for adolescents with Food-Induced Anaphylaxis (FIA) Sara F. Johnson, Roberta L. Woodgate A4 Outcomes matched related and unrelated bone marrow transplantation after reduced-toxicity conditioning children suffering from...
Phenylketonuria (PKU) is a relatively common autosomal recessive disorder. The frequency of PKU among Caucasians populations approximately 1:10.000. primarily consequence deficiency in phenylalanine hydroxylase (PAH) activity, and un-treated patients develop severe mental retardation. absence this enzymatic activity causes disturbances tyrosine tryptophan metabolism diminished formation catecholamine (dopamine), melanin serotonin. In the present study, nucleotide sequence mutations were...
ABSTRACT STAT6 (Signal transducer and activator of transcription 6) is a factor that plays central role in the pathophysiology allergic inflammation. mediates biological effects IL-4, cytokine necessary for type 2 differentiation T cells B cell survival, proliferation class switching to IgE. We have identificated two unrelated patients with phenotype notable their early-life onset profound immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia esosinophilic...