A5062518631- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Bone Tissue Engineering Materials
- Cervical and Thoracic Myelopathy
- Spinal Cord Injury Research
- Management of metastatic bone disease
- Musculoskeletal pain and rehabilitation
- Trauma Management and Diagnosis
- Spondyloarthritis Studies and Treatments
- Scoliosis diagnosis and treatment
- Hip and Femur Fractures
- Trauma and Emergency Care Studies
- Mesenchymal stem cell research
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopaedic implants and arthroplasty
- Bone and Joint Diseases
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Hip disorders and treatments
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- Shoulder and Clavicle Injuries
- Cardiac, Anesthesia and Surgical Outcomes
University Medical Center Utrecht
2016-2025
University Hospital Heidelberg
2010-2024
Heidelberg University
2010-2024
University of Toronto
2024
Utrecht University
2012-2023
Financial Research (Hungary)
2020
Rijnstate Hospital
2020
National Jewish Health
2019
University of Colorado Denver
2019
University of Memphis
2019
In Brief Study Design. Reliability and agreement study, retrospective case series. Objective. To develop a widely accepted, comprehensive yet simple classification system with clinically acceptable intra- interobserver reliability for use in both clinical practice research. Summary of Background Data. Although the Magerl thoracolumbar injury (TLICS) are well-known schemes to describe (TL) fractures, no TL has achieved universal international adoption. This lack consensus limits communication...
In bone regenerative medicine there is a need for suitable substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit applicability, especially with respect to 3D bioprinting. this study, we modified the naturally occurring extracellular matrix glycosaminoglycan hyaluronic acid (HA), in order yield photo-crosslinkable hydrogels increased mechanical stiffness long-term stability, minimal decrease cytocompatibility....
Disc prosthesis surgery is rapidly becoming an option in treating patients with symptomatic degenerative disc disease. Only short-term and midterm results are described the literature. Most operated belong to age group of 30–50 years. In these active patients, complications can be expected increase longer follow-up, similar total joint replacements extremities. Reported here a series 27 from another institution, who presented unsatisfactory or after SB Charité replacement. The objective this...
Contemporary understanding of the biomechanics, natural history, and methods treating thoracolumbar spine injuries continues to evolve. Current classification schemes these injuries, however, can be either too simplified or overly complex for clinical use.The Spine Trauma Group was given a survey identify similarities in treatment algorithms common as well characteristics injury that played key role decision-making process.Based on survey, has developed system an severity score...
In this study we investigated the bone-forming capacity of tissue-engineered (TE) constructs implanted ectopically in goats. As cell survival is questionable large animal models, significance vitality, and thus whether living cells instead only potentially osteoinductive extracellular matrix are required to achieve bone formation. Vital TE porous hydroxyapatite (HA) covered with differentiated marrow stromal (BMSCs) within an (ECM) were compared identical that devitalized before...
At present, it is well known that populations of human bone marrow stromal cells (HBMSCs) can differentiate into osteoblasts and produce bone. However, the amount with osteogenic potential ultimately obtained will still be dependent on both patient physiological status culture system. In addition, to use a cell therapy approach in orthopedics, large numbers required and, as result, knowledge factors affecting growth kinetics these needed. present study we investigated effect dexamethasone...
The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation growth factors into bioprinted offers many new possibilities regarding both biological and architectural properties the scaffolds. This study investigates whether sustained release morphogenetic protein 2 (BMP-2) influences osteogenicity engineered constructs. BMP-2 loaded on gelatin microparticles (GMPs) was used as system, which dispersed hydrogel-based constructs compared to...