Germano Di Sciascio

ORCID: 0000-0003-0862-3619
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About
Contact & Profiles
Research Areas
  • Coronary Interventions and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Valve Diseases and Treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Health and Disease Prevention
  • Cardiac Arrhythmias and Treatments
  • Cardiac and Coronary Surgery Techniques
  • Cardiovascular Function and Risk Factors
  • Adipokines, Inflammation, and Metabolic Diseases
  • Atherosclerosis and Cardiovascular Diseases
  • Health Systems, Economic Evaluations, Quality of Life
  • Acute Kidney Injury Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Congenital Heart Disease Studies
  • Viral Infections and Immunology Research
  • Cardiac electrophysiology and arrhythmias
  • Peripheral Artery Disease Management
  • Infective Endocarditis Diagnosis and Management
  • Cardiac pacing and defibrillation studies

Università Campus Bio-Medico
2014-2024

Campus Bio Medico University Hospital
2010-2024

Ospedale Garibaldi
2019-2020

Associazione Nazionale Medici Cardiologi Ospedalieri
2006-2017

Onze Lieve Vrouwziekenhuis Hospital
2015-2016

National Cancer Registry
2014

Bioengineering Center
2014

Itron (United States)
2014

American Heart Association
2013-2014

May Institute
2013

Aggressive platelet inhibition is crucial to reduce myocardial injury and early cardiac events after coronary intervention. Although observational data have suggested that pretreatment with a high loading dose of clopidogrel may be more effective than conventional dose, this hypothesis has never been tested in randomized trial.A total 255 patients scheduled undergo percutaneous intervention were 600-mg (n=126) or 300-mg (n=129) regimen given 4 8 hours before the procedure. Creatine kinase...

10.1161/01.cir.0000161383.06692.d4 article EN Circulation 2005-03-07

Background— Atrial fibrillation (AF) after cardiac surgery is associated with increased risk of complications, length stay, and cost care. Observational evidence suggests that patients who have undergone previous statin therapy a lower incidence postoperative AF. We tested this observation in randomized, controlled trial. Methods Results— Two hundred undergoing elective cardiopulmonary bypass, without treatment or history AF, were enrolled. Patients randomized to atorvastatin (40 mg/d,...

10.1161/circulationaha.106.621763 article EN Circulation 2006-09-26

Small myocardial infarctions after percutaneous coronary intervention have been associated with higher risk of cardiac events during follow-up. Observational studies suggested that statins may lower the procedural injury. The aim our study was to confirm this hypothesis in a randomized study.One hundred fifty-three patients chronic stable angina without previous statin treatment were enrolled study. Patients scheduled for elective atorvastatin (40 mg/d, n=76) or placebo (n=77) 7 days before...

10.1161/01.cir.0000137828.06205.87 article EN Circulation 2004-07-27

Objectives: Systemic inflammatory response occurs frequently after coronary artery bypass surgery, and it is strongly correlated with the risk of postoperative morbidity mortality. Recent studies demonstrate that treatment statin associated a significant marked decrease in inflammation-associated variables such as C-reactive protein, cytokines, adhesion molecules. Therefore, we investigated effects preoperative atorvastatin on systemic perioperative cardiopulmonary bypass. Design:...

10.1097/01.ccm.0000201407.89977.ea article EN Critical Care Medicine 2006-02-22

Impaired endothelial function is a key event in the atherosclerosis process and predicts future cardiovascular events subjects with without coronary artery disease (CAD). We performed first prospective study evaluating whether early measurement of brachial endothelium-dependent dilation (flow-mediated [FMD]) after stenting could predict occurrence in-stent-restenosis.The population included 136 patients single-vessel CAD undergoing percutaneous intervention (PCI) at least 6 months follow-up....

10.1161/01.cir.0000151308.06673.d2 article EN Circulation 2005-01-03

The prevention of stroke and the correct treatment carotid artery stenosis represent today a major debate in cardiovascular medicine. Beside endarterectomy, angioplasty stenting is becoming more widely performed for severe obstructive disease, now accepted as less invasive technique that may provide an alternative selected patients, particularly those with significant comorbidities. An Italian multidisciplinary task force, which converged most representative scientific societies involved...

10.1161/01.str.0000236101.09480.b7 article EN Stroke 2006-08-11

Abstract Objective: To prospectively evaluate the outcome with circulating endothelial progenitor cell (EPC) capture stent implantation in a cohort of consecutive patients high‐risk angiographic and/or clinical features. Background: Genous R‐stent™ is stainless steel coronary covered antibodies specific to EPC's surface antigens, designed promote formation confluent functional layer over device; conceivably, this may prevent both thrombosis and restenosis. Methods: From November 2005 March...

10.1002/ccd.21437 article EN Catheterization and Cardiovascular Interventions 2008-03-21
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