A5052244335- Ear Surgery and Otitis Media
- Olfactory and Sensory Function Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Otolaryngology and Infectious Diseases
- Obstructive Sleep Apnea Research
- Fibroblast Growth Factor Research
- Hearing Loss and Rehabilitation
- Streptococcal Infections and Treatments
- Vestibular and auditory disorders
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Tracheal and airway disorders
- Biochemical Analysis and Sensing Techniques
- Sinusitis and nasal conditions
- Respiratory and Cough-Related Research
- Advanced Chemical Sensor Technologies
- Neuroscience of respiration and sleep
- Bacterial Infections and Vaccines
- Otitis Media and Relapsing Polychondritis
- Ophthalmology and Eye Disorders
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Infectious Diseases and Tuberculosis
- Hearing Impairment and Communication
Aarhus University
2016-2025
Glostrup Hospital
2023-2025
Regionshospitalet Herning
2022-2024
Aarhus University Hospital
2010-2024
Central Denmark Region
2023
Regional Hospital West Jutland
2016-2022
Regional Hospital Holstebro
2009-2021
State of Illinois
2020
Louisiana State University
2018
Aalborg University Hospital
2013
Group A streptococci are commonly regarded as the most prevalent cause of acute bacterial tonsillitis and peritonsillar abscess (PTA). However, majority PTA aspirates also contain strains anaerobes, accumulating evidence indicates that Fusobacterium necrophorum (FN) could be involved in tonsillitis. The purpose present study was to describe epidemiology bacteriology Denmark, with particular emphasis on correlations between microbiological, clinical, laboratory data.A retrospective all...
Abstract Olfactory deficits are a common (often prodromal) symptom of neurodegenerative or psychiatric disorders. As such, olfaction could have great potential as an early biomarker disease, for example using neuroimaging to investigate the breakdown structural connectivity profile primary olfactory networks. We investigated suitability this purpose in two existing maps found problems with both terms their known secondary Based on these findings, we were able merge new template map networks...
Background Hypoparathyroidism following total thyroidectomy is globally the most common complication to thyroid surgery. The reported rates vary widely and might be highly dependent on surgical experience. In this study we aimed evaluate rate of hypoparathyroidism primary at a low-volume institution that only performs surgery does not have any experience with parathyroid Methods Retrospective cohort study. All patients undergoing ENT-Department, Goedstrup Hospital, Denmark, over 5-year...
The FGFR kinases are promising therapeutic targets in multiple cancer types, including lung and head neck squamous cell carcinoma, cholangiocarcinoma, bladder cancer. Although several kinase inhibitors have entered clinical trials, single-agent efficacy has been modest resistance invariably occurs. We therefore conducted a genome-wide functional screen to characterize mechanisms of inhibition FGFR1-dependent cellular model. Our identified known drivers, such as MET, additional novel...
Importance Hypoparathyroidism following thyroid surgery is a serious complication that occurs frequently when performed by low-volume surgeons without experience in parathyroid surgery. Objective To evaluate the occurrence of hypoparathyroidism total thyroidectomy after introduction autofluorescence low-volume, nonparathyroid institutions. Design, Setting, and Participants This prospective, multicenter cohort study, with follow-up period up to 1 year, was conducted Denmark at 2 institutions...
Necrotizing fasciitis of the head and neck is a rapidly progressing life-threatening condition. The purpose this study was to describe patients with focus on clinical presentation, microbiology, treatment, prognosis.Seventeen (10 men; median age, 54 years) were included. Nine underwent minor surgery immediately prior necrotizing fasciitis. typical course quickly spreading erythema, pronounced tenderness, severe pain. Imaging demonstrated diffuse swelling soft tissue, poorly differentiated...
Objectives The applicability of olfactory testing is dependent on cultural adaptation. aim this study was to validate the Sniffin' Sticks (Burghart Messtechnik, Wedel, Germany) threshold (T), discrimination (D), and identification (I) olfaction test. This data subsequently used investigate external validity international normative values separate hyposmia from normosmia. Methods included 388 participants. first step a questionnaire in which 238 adults rated their familiarity with 125 odor...
Cubilin and megalin are multifunctional endocytotic receptors expressed in many absorptive epithelia. The have separate functions but may act concert several tissues including the small intestine, visceral yolk sac renal proximal tubule to perform significant physiological essential homeostasis extracellular fluid compartments. Because of importance inner ear, we investigated expression cubilin this structure. Furthermore, examined binding properties 6 different aminoglycosides (AGs)...
Background: The Centor criteria and the streptococcal rapid antigen detection test (RADT) are commonly used to differentiate sore throat patients with group A streptococci (GAS) from other pathogens. We aimed investigate if procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC), absolute neutrophil (ANC) could increase diagnostic accuracy when added score RADT, or be instead of in differential diagnosis. Methods: 6-month prospective study was carried out a Danish general...
Abstract Objective: Cholesteatoma patients have a high risk of recurrence with complications, and knowledge exchange is prerequisite for improving treatment. This study aimed to apply appropriate statistics provide meaningful transferable results from cholesteatoma surgery, highlight independent prognostic factors, assess the incidence rate. Methods: Incidence rates were assessed district Aarhus, Denmark. From 147 operated on mainly canal wall up mastoidectomies debuting cholesteatomas,...
Abstract Objective To investigate the predictive value of tubomanometry (TMM) in predicting subjective outcome Balloon Eustachian Tuboplasty (BET) patients with long‐lasting tube dysfunction (ETD). Study Design Retrospective case series. Setting Single tertiary referral center. Methods A total 111 ETD undergoing 194 BET procedures were included. Demographics, TMM measurements, and tympanograms registered before 3 to 6 months after BET. The time ratio between pressure increase nasopharynx...
Positron emission tomography (PET) was used to investigate the neural systems involved in central processing of different auditory stimuli. Noise, pure tone and pure-tone pulses, music speech were presented monaurally. O-15-water PET scans obtained relation these stimulations five normal hearing healthy subjects. All stimuli related a basic scan silence. Processing simple stimuli, such as tones noise, predominantly activate left transverse temporal gyrus (Brodmann area [BA] 41), whereas...