A5085934194- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Sleep and Wakefulness Research
- Sleep and related disorders
- Cardiovascular and Diving-Related Complications
- EEG and Brain-Computer Interfaces
- Tracheal and airway disorders
- Sleep and Work-Related Fatigue
- Dysphagia Assessment and Management
- Cardiovascular Disease and Adiposity
- Restless Legs Syndrome Research
- Context-Aware Activity Recognition Systems
- Gastroesophageal reflux and treatments
- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Time Series Analysis and Forecasting
- Cardiovascular Syncope and Autonomic Disorders
- Diet and metabolism studies
- Voice and Speech Disorders
- Non-Invasive Vital Sign Monitoring
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Anomaly Detection Techniques and Applications
- Adipose Tissue and Metabolism
- Circadian rhythm and melatonin
Reykjavík University
2013-2025
National University Hospital of Iceland
2016-2025
University of Iceland
2009-2021
University of Pennsylvania
2009-2014
SleepMed
2009-2014
Circadian (United States)
2014
Barnaspítali
2013
Hospital of the University of Pennsylvania
2009
Summary This European guideline for the diagnosis and treatment of insomnia was developed by a task force Sleep Research Society, with aim providing clinical recommendations management adult patients insomnia. The is based on systematic review relevant meta‐analyses published till June 2016. target audience this includes all clinicians involved in insomnia, patient population adults chronic disorder. GRADE (Grading Recommendations Assessment, Development Evaluation) system used to grade...
Although commonly observed in clinical practice, the heterogeneity of obstructive sleep apnoea (OSA) presentation has not been formally characterised. This study was first to apply cluster analysis identify subtypes patients with OSA who experience distinct combinations symptoms and comorbidities. An baseline data from Icelandic Sleep Apnoea Cohort (822 newly diagnosed moderate-to-severe OSA) performed. Three clusters were identified. They classified as "disturbed group" (cluster 1),...
The aim was to assess the prevalence of obstructive sleep apnoea (OSA) as defined by an apnoea–hypopnea index (AHI) ≥15 in middle-aged general population, and interrelationship between OSA, sleep-related symptoms, sleepiness vigilance. A population sample 40–65-year-old Icelanders invited participate a study protocol that included type 3 study, questionnaire psychomotor vigilance test (PVT). Among 415 subjects 56.9% had no OSA (AHI <5), 24.1% mild 5–14.9), 12.5% moderate 15–29.9), 2.9%...
A recent study of patients with moderate-severe obstructive sleep apnea (OSA) in Iceland identified three clinical clusters based on symptoms and comorbidities. We sought to verify this finding a new cohort examine the generalizability OSA an international ethnically diverse cohort.Using data 972 (apnea-hypopnea index [AHI] ≥ 15 events per hour) recruited from Sleep Apnea Global Interdisciplinary Consortium (SAGIC), we performed latent class analysis 18 self-reported symptom variables,...
To assess the changes of insomnia symptoms among patients with obstructive sleep apnea (OSA) from starting treatment positive airway pressure (PAP) to a 2-y follow-up.
Distinct clinical phenotypes of obstructive sleep apnea (OSA) have been identified: Disturbed Sleep, Minimally Symptomatic, and Sleepy. Determining whether these respond differently to standard treatment helps us create a foundation for personalized therapies. We compared responses positive airway pressure (PAP) therapy in OSA phenotypes. The study sample included 706 patients from the Icelandic Sleep Apnea Cohort with moderate-to-severe who were prescribed PAP. Linear logistic mixed models...
To assess the relative roles and interaction of obstructive sleep apnea (OSA) severity obesity on interleukin-6 (IL-6) C-reactive protein (CRP) levels.Cross-sectional cohort.The Icelandic Sleep Apnea Cohort.454 untreated OSA patients (380 males 74 females), mean ± standard deviation age 54.4 10.6 yr.N/A.Participants underwent a study, abdominal magnetic resonance imaging to measure total visceral fat volume, had fasting morning IL-6 CRP levels measured in serum. A significantly higher...
Summary Obstructive sleep apnea leads to recurrent arousals from sleep, oxygen desaturations, daytime sleepiness and fatigue. This can have an adverse impact on quality of life. The aims this study were compare: (i) life between the general population untreated patients with obstructive apnea; (ii) changes among after 2 years positive airway pressure treatment adherent non‐users. Propensity score methodologies used in order minimize selection bias strengthen causal inferences. enrolled...
To address whether changes in gene expression blood cells with sleep loss are different individuals resistant and sensitive to deprivation.Blood draws every 4 h during a 3-day study: 24-h normal baseline, 38 of continuous wakefulness subsequent recovery sleep, for total 19 time-points per subject, 2-h psychomotor vigilance task (PVT) assessment when awake.Sleep laboratory.Fourteen subjects who were previously identified as behaviorally (n = 7) or deprivation by PVT.Thirty-eight hours...
Abstract Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely is Epworth Sleepiness Scale (ESS). However, it unclear if using ESS adequate on its own when assessing EDS. The aim of this study was estimate characteristics and prevalence EDS Basic Nordic Sleep Questionnaire (BNSQ) in general population samples. Participants aged 40 years older answered questions about sleepiness, health, sleep‐related symptoms quality life. Two groups...
Current diagnostic parameters estimating obstructive sleep apnoea (OSA) severity have a poor connection to the psychomotor vigilance of OSA patients. Thus, we aimed investigate how apnoeas, hypopnoeas and intermittent hypoxaemia is associated with impaired vigilance.We retrospectively examined type I polysomnography data corresponding tasks (PVTs) 743 consecutive patients (apnoea-hypopnoea index (AHI) ≥5 events·h-1). Conventional (e.g. AHI oxygen desaturation (ODI)) novel obstruction...
Determining sleep stages accurately is an important part of the diagnostic process for numerous disorders. However, as stage scoring done manually following visual rules there can be considerable variation in staging between different scorers. Thus, this study aimed to comprehensively evaluate inter-rater agreement staging. A total 50 polysomnography recordings were scored by 10 independent scorers from seven centres. We used scorings calculate a majority score taking that was most each...
Visceral adipose tissue (VAT) is associated with abnormal cardiovascular and metabolic profiles. Total VAT volume of the abdominal compartment by magnetic resonance imaging (MRI) gold-standard measurement for but costly time consuming. Prior studies suggest area on a single slice MR image may serve as surrogate total it unknown if this relationship maintained in overweight obese men women. Untreated sleep apnea subjects enrolled into Icelandic Sleep Apnea Cohort (ISAC) underwent MRI....
Study Objectives:The aims of this study were: (1) to use a standardized psychiatric interview, conducted by trained psychologist assess the prevalence depression among patients with untreated OSA, and (2) identify if OSA severity or other comorbid disorders (insomnia, hypertension, diabetes) are related OSA.Methods: Participants were newly diagnosed (n = 284) waiting start positive airway pressure (PAP) treatment.The Mini International Neuropsychiatric Interview (MINI) was used...
<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective:</i> Obstructive sleep apnea (OSA) is diagnosed using the apnea-hypopnea index (AHI), which average number of respiratory events per hour sleep. Recently, machine learning algorithms for automatic AHI assessment have been developed, but many them do not consider individual stages or events. In this study, we aimed to develop a deep model simultaneously score both and The hypothesis was...
The objective of this study was to compare each other the methods currently recommended by American Academy Sleep Medicine (AASM) measure snoring: an acoustic sensor, a piezoelectric sensor and nasal pressure transducer (cannula). Ten subjects reporting habitual snoring were included in study, performed at Landspitali-University Hospital, Iceland. Snoring assessed listening air medium microphone located on patient's chest, compared two overhead microphones (stereo) manual scoring cannula...
<h3>Objectives</h3> To estimate the prevalence and characteristics of frequent nocturnal sweating in obstructive sleep apnoea (OSA) patients compared with general population evaluate possible changes positive airway pressure (PAP) treatment. Nocturnal can be very bothersome to patient bed partner. <h3>Design</h3> Case–control longitudinal cohort study. <h3>Setting</h3> Landspitali—The National University Hospital, Iceland. <h3>Participants</h3> The Icelandic Sleep Apnea Cohort consisted 822...