A5063499341- Anesthesia and Pain Management
- Nausea and vomiting management
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Pain Management and Opioid Use
- Shoulder Injury and Treatment
- Peripheral Nerve Disorders
- Orthopedic Surgery and Rehabilitation
- Intraocular Surgery and Lenses
- Dental Anxiety and Anesthesia Techniques
- Anesthesia and Neurotoxicity Research
- Reconstructive Surgery and Microvascular Techniques
- Ureteral procedures and complications
- Case Reports on Hematomas
- Intensive Care Unit Cognitive Disorders
- Posttraumatic Stress Disorder Research
- Pediatric Pain Management Techniques
- Urological Disorders and Treatments
- Autoimmune Neurological Disorders and Treatments
- Anatomy and Medical Technology
- Electrocatalysts for Energy Conversion
- Infectious Encephalopathies and Encephalitis
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare professionals’ stress and burnout
University Hospital of Geneva
2006-2024
University of Geneva
2019-2024
Geneva College
2005-2009
National Interuniversity Consortium of Materials Science and Technology
2008
École Nationale Supérieure des Mines de Paris
2008
Institute for Energetics and Interphases
2008
Centre des Matériaux
2008
University of Genoa
2008
Université de Bourgogne
2008
Hôpital Beau-Séjour
2006
The usefulness of peripheral nerve blockade in the anesthetic management hip surgery has not been clearly established. Because sensory afferents from include several branches lumbar plexus, authors hypothesized that a plexus block could reduce pain major procedure.In double-blind prospective trial, 60 patients undergoing total arthroplasty were randomized to receive general anesthesia with (plexus group, n = 30) or without (control posterior block. was performed after induction using...
We tested the effect of epinephrine added to 20 mL ropivacaine 0.5% and 0.2% on postoperative analgesia via a femoral catheter after total knee replacement. Forty-one patients undergoing replacement under combined peripheral block/general anesthesia were randomly allocated two groups. After insertion catheter, 21 in Ropivacaine-Epinephrine (ROPI-EPI) group received plus 1:200,000, whereas Ropivacaine (ROPI) plain 0.5%. Thereafter, sciatic block with 30 bupivacaine 1:200,000 was performed all...
Background: We designed this study to compare the postoperative analgesic effects of intrathecal morphine and nalbuphine, endpoints being onset offset action. Methods: Geriatric patients scheduled for elective total hip replacement under continuous spinal anaesthesia were randomized two double‐blinded groups in recovery room as soon they experienced a pain score higher than 3 cm on visual analogue scale (VAS, 0–10 cm). Either 160 μg or 400 nalbuphine 4 ml normal saline administered...
Levobupivacaine and ropivacaine are 2 left enantiomeric molecules frequently used for peripheral nerve blocks because of their safe clinical profile. is more lipophilic theoretically potent than ropivacaine, but studies show conflicting results in terms anesthetic analgesic characteristics. We hypothesized that the pure S-enantiomer bupivacaine provides longer-lasting analgesia ropivacaine.We compared characteristics 20 mL levobupivacaine versus 0.5% a posterior sciatic block (Labat...
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumour of the skin. While localised disease carries an overall favourable prognosis, metastatic associated with poor clincal outcomes. Most cases MCC are managed systemic chemotherapy or immunotherapy, though 5-year survival for these patients remains dismal 17%. Here, we present case 79-year-old man right ear metastases to regional lymph nodes, ipsilateral parotid gland and thoracic spine. He was treated combination first-line...
Polymers with different hydrophilic groups [polyvinylpyrrolidone (PVP), ammonium polyacrylate (APA), and hydroxypropylmethyl cellulose (HPMC)] surfactants [cetyltrimethylammonium bromide (CTAB) sodium dodecylbenzensulfonate (SDBS)] were used as additives to modify the crystallization of β-Ni(OH)2 in hydrothermal conditions. Marked morphological changes particles observed depending on additive concentration duration treatment. The final morphology is result a complex, time-dependent...
Introduction Whether a popliteal plexus block improves postoperative pain following total knee arthroplasty remains debated. This randomized trial tested if adding to continuous femoral nerve decreases opioid requirement. Methods We included 66 patients undergoing arthroplasty. 32 received and (intervention), 34 alone (control). The primary endpoint was the 12-hour morphine-equivalent consumption (mg). Secondary outcomes consumption, Visual Analog Pain Score (0–10), sensorimotor extension of...
The attempts to explain the unpredictability of extent spinal block provided by plain local anesthetic solutions have resulted in many clinical reports; however, causes this uncertainty are as yet unknown. Recently, normal values human cerebrospinal fluid densities been studied showing important interindividual variations, especially between females and males. current study was designed evaluate primary endpoint influence density on with bupivacaine. ancillary endpoints were search factors...
We designed this study to compare the postoperative analgesic effects of intrathecal fentanyl and sufentanil, end points being onset, quality, duration action. A total 42 geriatric patients, scheduled for elective hip replacement under continuous spinal anesthesia, were randomized in two double-blinded groups as soon they experienced a pain score higher than 3 10 on visual analog scale recovery room. Either 7.5 μg sufentanil or 40 2 mL normal saline intrathecally administered. Pain scores,...
In Brief Total hip arthroplasty (THA) is frequently performed under spinal anesthesia using either isobaric or hypobaric anesthetic solution. However, these two solutions have never been compared similar surgical conditions. the present study, we and hemodynamic effects of bupivacaine in 40 ASA physical status I–II patients undergoing THA lateral decubitus position anesthesia. With operative side up, randomly received, a double-blinded manner, injection 3.5 mL (17.5 mg) plain mixed with 1.5...
EDITOR: Femoral nerve block is frequently used for pain control after total knee replacement (TKR) [1-5]. Although one study concluded that a supplemental sciatic did not improve further the analgesic efficacy [6], our findings disagree. We report results of an open clinical observational made in patients undergoing TKR under spinal anaesthesia with standardized protocol postoperative analgesia carried out institution. Pain relief was provided by local anaesthetic administered via indwelling...
<h3>Background</h3> There is controversy about the effectiveness of perineural clonidine used as an adjuvant to local anesthetics. This study investigated whether addition 150 μg 0.5% levobupivacaine for posterior sciatic nerve block would prolong duration analgesia. <h3>Methods</h3> double-blind, prospective trial compared analgesic characteristics 20 mL plain versus plus in a (Labat approach) foot and ankle surgery. Sixty patients were randomized allocated receive either alone or...
We designed this study to compare the postoperative analgesic effects of intrathecal fentanyl and sufentanil, end points being onset, quality, duration action. A total 42 geriatric patients, scheduled for elective hip replacement under continuous spinal anesthesia, were randomized in two double-blinded groups as soon they experienced a pain score higher than 3 10 on visual analog scale recovery room. Either 7.5 μg sufentanil or 40 2 mL normal saline intrathecally administered. Pain scores,...
In our clinical experience, sufentanil is more effective when administered intrathecally than intravenously. To test this hypothesis, we compared the analgesic characteristics of 7.5 microg intrathecal or intravenous for pain relief after total-hip replacement.A randomized, double-blind study was conducted 40 patients older 75 years who experienced arthroplasty in which continuous spinal anesthesia administered. recovery room, as soon a score higher 3 on scale 10 visual analog reported,...
Chronic pain after major lower back surgery is frequent. We investigated in adults the effect of perioperative low-dose ketamine on neuropathic pain, assessed by DN4 questionnaire, 6 and 12 months surgery.In this single-centre randomized trial, 80 patients received intravenous 0.25 mg/kg preoperatively, followed mg kg-1 hr-1 intraoperatively, 0.1 from 1 hr before end until recovery room stay; controls placebo.Preoperatively, 47.4% group 46.3% placebo had pain; 10% 3.8%, respectively, were...
Meningitis, encephalitis, and myelitis are various forms of acute central nervous system (CNS) inflammation, which can coexist lead to serious sequelae. Known aetiologies include infections immune-mediated processes. Despite advances in clinical microbiology over the past decades, cause CNS inflammation remains unknown approximately 50% cases. High-throughput sequencing was performed search for viral sequences cerebrospinal fluid (CSF) samples collected from 26 patients considered have...
We describe a partial sensory and motor block of the ipsilateral lower limb after interscalene infusion. After injection 20 mL ropivacaine through needle, catheter was advanced 5 cm, an infusion 0.2% mL/h commenced. Six hours later, patient reported left hemisyndrome, which resolved discontinued. Cervical computed tomography showed tip close to intervertebral foramen at C7-T1 level several intravertebral paramedullar air bubbles. conclude that neurological symptoms were caused by local...
Using intrathecal (IT) sufentanil has recently become popular for analgesia in labor because it provides rapid and profound pain relief the absence of motor sympathetic block [1]. All published reports respiratory depression after administration IT have occurred laboring patients [2-6]. In our institution, is also administered using an indwelling catheter postoperative major orthopedic surgery geriatric patients. We present a case occurring single injection 5 [micro sign]g patient who...
Using intrathecal (IT) sufentanil has recently become popular for analgesia in labor because it provides rapid and profound pain relief the absence of motor sympathetic block [1]. All published reports respiratory depression after administration IT have occurred laboring patients [2-6]. In our institution, is also administered using an indwelling catheter postoperative major orthopedic surgery geriatric patients. We present a case occurring single injection 5 [micro sign]g patient who...