A5084466918- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Infectious Diseases and Mycology
- Cutaneous lymphoproliferative disorders research
- Infections and bacterial resistance
- Actinomycetales infections and treatment
- T-cell and Retrovirus Studies
- Autoimmune and Inflammatory Disorders
- Phytoplasmas and Hemiptera pathogens
- Infectious Diseases and Tuberculosis
- Eosinophilic Disorders and Syndromes
- Health, Education, and Cultural Studies
- Sarcoidosis and Beryllium Toxicity Research
- Enterobacteriaceae and Cronobacter Research
- Women's cancer prevention and management
- Syphilis Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Beetle Biology and Toxicology Studies
- Toxoplasma gondii Research Studies
- Plant-Microbe Interactions and Immunity
- Dermatological diseases and infestations
- Vector-borne infectious diseases
- Streptococcal Infections and Treatments
Complejo Asistencial Universitario de Palencia
2025
Fundação Oswaldo Cruz
2015-2024
Brigham and Women's Hospital
2024
Instituto Evandro Chagas
2005-2022
Ministério da Saúde
2022
Faculdades Oswaldo Cruz
2013-2022
Hospital Geral de Bonsucesso
2019
AVM Faculdade Integrada
2015
Institute of Dermatology
2011
Universidade de São Paulo
2009
In the scientific literature, sporotrichosis has traditionally been associated with agricultural work, since causative agent is found naturally in soil. However, cases have reported recently an urban area, related to zoonotic transmission. The current study aimed contribute knowledge on area through exploratory analysis of its socio-spatial distribution Rio de Janeiro, Brazil, from 1997 2007, identifying areas heaviest database Health Surveillance Service at Evandro Chagas Institute for...
Sporotrichosis is the most common subcutaneous mycosis in South America. Classic infection associated with traumatic inoculation of soil, vegetables, and organic matter contaminated Sporothrix schenckii. Zoonotic transmission has been described isolated cases or small outbreaks. Since 1998, we have observing an increasing number sporotrichosis persons from city Rio de Janeiro, Brazil, surroundings. From 1998 to 2001, 178 culture-proven had diagnosed. Female patients predominated, median age...
Background There have been several recent changes in the taxonomy of Sporothrix schenckii as well new observations regarding clinical aspects sporotrichosis. In this study, we determined identification species associated with both classic and unusual sporotrichosis observed endemic area Rio de Janeiro, Brazil. Methodology/Principal Findings To verify whether S. brasiliensis is manifestations sporotrichosis, a cross-sectional study was performed which isolates from 50 patients different were...
Sporotrichosis is endemic in Rio de Janeiro, Brazil, and cases have been reported to be associated with HIV. This article describes the clinical manifestations evolution of sporotrichosis HIV-positive patients constitutes largest case series date. There were 21 diagnosed by recovery etiologic agent from 1999–2009. Sixteen (76.2%) men five (23.8%) women, a mean age 41.2 years. Seven these individuals previously unaware their HIV infection. Mean CD4 count was 346.4 cells/μl. The most frequent...
Twenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying emergence mycosis, some progress been made, including expansion a research network field and higher visibility within government authorities funding agencies. However, there are still challenges to curbing coming years. These include development rapid accurate diagnostic tests, new antifungal...
During the period from 1987 to 1998, 13 cases of human sporotrichosis were recorded at Research Center Evandro Chagas Hospital (CPqHEC) in Rio de Janeiro. Two these patients related scratch by a sick cat. subsequent July 1998 2000, 66 human, 117 cats and 7 dogs with diagnosed CPqHEC. Fifty-two humans (78.8%) reported contact sporotrichosis, 31 (47%) them reporting history or bite. This epidemic, unprecedented literature, involving cats, beings may have started insidiously before 1998.
Sporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting large at-risk population, which includes HIV-infected individuals. We assessed patients co-infected by Sporothrix spp. and HIV over time the context of an unabated sporotrichosis epidemic. A retrospective cohort retrieved information from National reference institute for infectious diseases regarding 48 sporotrichosis-HIV co-infection (group 1) as well 3,570 2),...
Overcrowding is a significant factor contributing to endemic infection with Sarcoptes scabiei in human and animal populations. However, since scabies mites from different host species are indistinguishable morphologically, it unclear whether people can be infected scabies-infested animals. Molecular fingerprinting was done using three S. scabiei-specific single locus hypervariable microsatellite markers, combined total of 70 known alleles. Multilocus analysis 712 dog hosts Ohio, Panama...
Abstract Background Sporotrichosis most commonly presents as a localized lymphocutaneous infection following traumatic inoculation of soil, vegetables or organic substrates contaminated with the dimorphic fungus Sporothrix schenckii . Cases widespread cutaneous lesions are rare. There have been isolated reports household outbreaks sporotrichosis involving cats and humans. Methods We report 24 cases culture‐proven presenting lesions. Results These part an epidemic currently occurring in Rio...
Transmission of Paracoccidioides spp. fungi to humans is usually related manipulation soil. Rural workers are the most affected group. We report an outbreak paracoccidioidomycosis after deforestation and massive earth removal during construction a highway in Rio de Janeiro, Brazil. Extensive environmental disturbances might be involved fungal transmission.
Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Brazil accounts for approximately 80% of cases, where it represents major public health issue due its disabling impact and the number premature deaths causes. We present retrospective cohort study that was conducted in order better understand factors relate cure infection treatment 200 patients with PCM. evaluated influence sociodemographic clinical as well therapeutic regimen (trimethoprim–sulfamethoxazole...
Since 1998 a cat-transmitted epidemic of sporotrichosis has been observed in Rio de Janeiro (RJ), Brazil. Besides the lymphocutaneous and fixed forms, other presentations, such as disseminated cutaneous mucosal involvement, well for first time, erythema nodosum multiforme have reported associated with sporotrichosis. This study investigates phenotypes genotypes Sporothrix schenckii isolates recovered from different clinical forms disease noted part this epidemic. A total 88 59 cases 29...
Introduction The agents of paracoccidioidomycosis, historically identified as Paracoccidioides brasiliensis, are in fact different phylogenetic species. This study aims to evaluate associations between species and corresponding clinical data. Methods strains from INI/Fiocruz patients (1998–2016) were recovered. Socio-demographic, epidemiological, clinical, serological, therapeutic prognostic data the collected possible these variables with fungal through partial sequencing ADP-ribosylation...
Purpose To describe 26 cases of bulbar conjunctival sporotrichosis.Methods Review clinical records patients with conjunctivitis due to culture-proven Sporothrix spp. infection, in Rio de Janeiro, from 2007 2017.Results Twenty-six were identified. Median age was 25 years. Adults more affected (53.8%), followed by adolescents (26.9%). There a predominance women (73.1%). Twenty-four (96%) reported contact cats sporotrichosis. Twenty-one (80.8%) presented primary ocular Five associated eyelid...
Sporotrichosis is a subcutaneous mycosis with global distribution, and patients generally receive outpatient treatment. Since 1998 there has been an increase in cases the state of Rio de Janeiro, Brazil, mainly via zoonotic transmission involving cats. Patients coinfected human immunodeficiency virus (HIV) often require hospitalization evolve to death. This study analyzes describes data from 1992 2015 obtained database Brazilian Unified National Health System (SUS). There were 782...
Meningeal sporotrichosis is rare and occurs predominantly in immunosuppressed individuals. This retrospective study explored clinical laboratory characteristics, treatment, prognosis of patients with disseminated who underwent lumbar puncture (LP) at a Brazilian reference center from 1999 to 2020. Kaplan-Meier Cox regression models were used estimate overall survival hazard ratios. Among 57 enrolled patients, 17 had meningitis. Fifteen (88.2%) HIV infection, 6 them, neurological...
Although rare, disseminated sporotrichosis is increasing in several countries. Despite its limiting toxic potential, amphotericin B the only intravenous antifungal available to treat severe sporotrichosis. We aimed describe effectiveness and safety of treatment for Clinical records patients with at a reference center were reviewed. This study included 73 patients. Most (53.4%) men non-white. HIV coinfection was main comorbidity (52.1%). reported contact cats (76.7%). Sporothrix brasiliensis...
Sporotrichosis in childhood is rare most countries. Isolated cases and small outbreaks related to recreational activities or without identification of the transmission mechanism have been reported.Series case reports. The isolation Sporothrix schenckii from exudates fragments lesions obtained patients was used as criterion inclusion study.A total 81 sporotrichosis children younger than 15 years age were diagnosed at Evandro Chagas Research Institute, Fiocruz, Brazil, between 1998 2004. These...
INTRODUCTION: Neuroparacoccidioidomycosis (NPCM) is a term used to describe the invasion of central nervous system by pathogenic fungus Paracoccidioides brasiliensis. NPCM has been described sporadically in some case reports and small series, with little or no focus on treatment outcome long-term follow-up. METHODS: All patients from January 1991 December 2006 were analyzed followed until 2009. RESULTS: Fourteen (3.8%) cases identified out 367 paracoccidioidomycosis (PCM). A combination oral...
Sporotrichosis is a subacute to chronic infection caused by members of the Sporothrix schenckii complex. Itraconazole first choice antifungal drug for treating this infection, with terbinafine and potassium iodide as alternatives amphotericin B used in cases severe infections. Correlation susceptibility data clinical outcome patients scarce. The aim study was correlate mycological refractory sporotrichosis. In work, susceptibilities, determined according reference M38-A2 CLSI protocol, 25...