In recent decades, an alarming increase in the number of sporotrichosis cases has been reported southern and southeastern Brazil, especially state Rio de Janeiro, considered a long-term hyperendemic condition associated with feline transmission. According to phenotypic classifications, Sporothrix species recovered from cats were classified as S. brasiliensis 96.5% studied cases. This finding also demonstrated humans, which confirms zoonotic transmission this predominant Brazil. The fungus...

Sporotrichosis is a subcutaneous mycosis with global distribution, and patients generally receive outpatient treatment. Since 1998 there has been an increase in cases the state of Rio de Janeiro, Brazil, mainly via zoonotic transmission involving cats. Patients coinfected human immunodeficiency virus (HIV) often require hospitalization evolve to death. This study analyzes describes data from 1992 2015 obtained database Brazilian Unified National Health System (SUS). There were 782...

Sporotrichosis is a subacute/chronic subcutaneous mycosis. Since the late 1990s, there has been hyperendemic zoonotic transmission in state of Rio de Janeiro, involving Sporothrix brasiliensis, most virulent causative species, and "belt" was described along limits between capital its outskirts ("Baixada Fluminense"). This study analyzes distribution sporotrichosis using secondary data from Notifiable Diseases Information System (Sinan) Janeiro State Health Department (SES/RJ) 2011 to 2015...

Paracoccidioidomycosis (PCM) is a neglected endemic mycosis in Latin America. Most cases occur Brazil. It classified as PCM infection and disease subdivided into chronic (adult type) or acute (juvenile disease, with the latter being less frequent more severe. In 2016, we reported an increase numbers of patients diagnosed after highway’s construction. We conducted study at INI-Fiocruz, reference center for infectious diseases, including mycoses, Rio de Janeiro, Brazil, aiming to deepen...

We report a healthy, 44-year-old woman presenting with an at least 20-year history of hardened papules in the forehead region, extending to scalp. The biopsy and histopathologic exam confirmed diagnosis osteoma cutis. review literature discuss classification cutaneous ossification process presented, along results surgical treatment.

Paracoccidioidomycosis (PCM) is one of the main endemic systemic mycoses in Latin America, usually occurring rural areas. When PCM occurs simultaneously with underlying immunosuppressive conditions, it can present as an opportunistic disease. Between 2000 and 2017, literature reported around 200 cases people living HIV/AIDS (PLWHA). To address research gaps on this co-infection to study its possible temporal changes last decade, we performed active case search cohorts from a Brazilian...

Tinea nigra is a superficial fungal infection caused by Hortaea werneckii. It typically affects young individuals as an asymptomatic unilateral macule, from light brown to black on the palms and soles, mainly in tropical subtropical regions. In 1997, Gupta et al. [Br J Dermatol 1997;137:483-484] described dermoscopic characteristics of tinea nigra. Topical antifungals with or without keratolytic agents can be used for treatment. The authors report case 47-year-old man macules bilaterally...

Nevus comedonicus is a rare cutaneous anomaly, characterized by the clustering of papules with firm, blackened horny buffers. It in general has zosteriform pattern and affects both genders equally. In some patients, there formation cysts, abscesses, fistulas, aggravating its psychosocial impact. The association extracutaneous lesions characterizes nevus syndrome. Despite several therapeutic options, result unsatisfactory most cases. We report case man an exuberant congenital lesion,...

Neuroparacoccidioidomycosis (NPCM) is a rare and severe clinical presentation of paracoccidioidomycosis (PCM). We performed retrospective cohort study at the Evandro Chagas National Institute Infectious Diseases (INI/Fiocruz), reference center for PCM in state Rio de Janeiro, Brazil. All cases admitted to INI/Fiocruz from January 2007 December 2019 were reviewed. Eight (3.9%) among 207 patients met diagnostic criteria NPCM. The mean age was 44.6 years male:female ratio 7:1. presented...

Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin America, mostly Brazil. The involvement of the gastrointestinal tract uncommon and usually associated with acute form. Recently, cluster PCM cases has been described Rio de Janeiro, We report 42-year-old male, resident presenting chronic diarrhea abdominal pain past 3 years, previously diagnosed as Chron´s disease. When immunosuppressive therapy was prescribed, patient evolved worsening previous symptoms addition to...

The occurrence of acute paracoccidioidomycosis (PCM) in urban areas the Rio de Janeiro state, Brazil, has emerged recent years. Therefore, young populations, including pregnant women, are at a higher risk infection. Furthermore, women undergoing itraconazole treatment for PCM have increased chances to get because this medication may reduce effectiveness contraceptives. Acute is invasive, reaching abdominal organs, posing maternal-fetal risk. also challenging due teratogenicity associated...

Hepatitis C virus (HCV) chronically infects 0.5-3% of the world population. A large group patients develop cirrhosis and its complications. Since 2011, telaprevir boceprevir are used, improving disease evolution. One main side effects these drugs is skin eruption. We report a 53-year-old patient with due to HCV who started classic treatment associated telaprevir. In ninth week, he presented severe rash that required interruption this drug. emphasize importance early recognition appropriate...

Este trabalho propõe um novo mecanismo para aprovisionamento de identidade microsserviços baseado em evidências integridade. A solução proposta se baseia verificação integridade contêineres, cuja cadeia confiança é construída a partir chip TPM. Implementamos o modelo como plugin framework atestação, seguindo padrão emissão identidades. Avaliações foram realizadas fim analisar sobrecarga imposta ao sistema. Os resultados evidenciam desempenho eficiente da solução, com tempo médio uma 252 ms,...

Abstract The epidemiological dynamics of paracoccidioidomycosis (PCM) has been changing over the years. We analyzed secondary public data from Hospital Information System Brazilian Unified Health (SIH/SUS), focusing on PCM-related hospitalizations and in-hospital deaths. In period between 2010 2019, 396 30 deaths were related to PCM among 7 073 334 registered in Rio de Janeiro. highlight rising rates, reflecting increase number acute forms previously reported. Urgent health policies are...

Abstract The etiology of tinea capitis changes over time, mainly due to trend in migration. We report 19 cases caused by Microsporum audouinii, an uncommon agent South America, all them confirmed molecular methods. All patients were male. average age was 6.1 years. 15 residents Rio de Janeiro city and 4 from neighboring cities. Among the submitted follow-up, griseofulvin prescribed for 8 them. Due medication shortages, terbinafine 5 patients, needing be switched 3 cases, with a bigger total...

Tinea capitis (TC), primarily affecting children aged 3–7, has globally increased in prevalence, and Microsporum canis, a zoophilic fungi, Trichophyton tonsurans, an anthropophilic have become the major aetiologic agents.1 In 21st century, reports indicate increase number of cases transmission due to migrations, urbanization, changes lifestyle socioeconomic levels.1 audouinii, fungi endemic Africa, causes milder inflammatory chronic TC with late detection lack subjective symptoms, comparison...

A 45-year-old man (Case 1) from a rural area in the state of Rio de Janeiro, Brazil presented with 2-year history dry cough and an extensive ulcerated genital lesion (Fig 1, A). Chest radiography showed bilateral perihilar infiltrate. 56-year-old 2) countryside Janeiro 14-month tongue 2, A), dysphagia, weight loss. In both cases, clinical samples were collected for histologic examination using hematoxylin-eosin (Figs B B) Grocott methenamine silver C C) stains. Figures D depict development...

Author(s): Falcao, Eduardo Mastrangelo Marinho; Catharino, Alessandra Rodrigues; Zompero, Camila Machado; Kac, Bernard Kawa