A5102919727- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Milk Quality and Mastitis in Dairy Cows
- Heme Oxygenase-1 and Carbon Monoxide
- Identification and Quantification in Food
- Food Allergy and Anaphylaxis Research
- Infant Nutrition and Health
- Probiotics and Fermented Foods
- Medicinal Plants and Bioactive Compounds
- Animal Diversity and Health Studies
- Salmonella and Campylobacter epidemiology
- Thermal Regulation in Medicine
- Toxoplasma gondii Research Studies
- Biosensors and Analytical Detection
- Innovative Microfluidic and Catalytic Techniques Innovation
- Adsorption and biosorption for pollutant removal
- Meat and Animal Product Quality
- Optimism, Hope, and Well-being
- Microbial Inactivation Methods
- Bone Metabolism and Diseases
- RNA Interference and Gene Delivery
- Digestive system and related health
- Olfactory and Sensory Function Studies
- Nanocomposite Films for Food Packaging
- Escherichia coli research studies
Fudan University
2025
Shaanxi University of Science and Technology
2010-2024
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2023
China XD Group (China)
2021
Affiliated Hospital of Nantong University
2016-2019
Nantong University
2016-2019
Sun Yat-sen University
2016-2017
Science North
2016
Resveratrol (Res) has anti-inflammation and antiosteoporosis functions. We evaluated the effect of Res on osteoclast differentiation by releasing inflammatory cytokines from precursor RAW 264.7 cells stimulated lipopolysaccharide (LPS). In study, LPS (1 ng/L) was used to induce Raw injury model in vitro. A total 25 ng/mL M-CSF + 30 RANKL or plus 1 μg/L osteoclastogenesis experiments. utilized Cell Counting Kit-8 assay measure relative cell survival cells. Then, enzyme-linked immunosorbent...
Micro-inflammation plays an important role in the pathogenesis of spontaneously hypertensive rat (SHR). In present study, we investigated therapeutic potential resveratrol (RSV), a polyphenol with anti-fibrosis activity renal damage model. SHR model, RSV treatment blunted increase urine albumin excretion, urinary β2-microglobulin (β2-MG), attenuated decrease creatinine clearance rate (CCR). The glomerular sclerosis index (1.54±0.33 compared 0.36±0.07) and tubulointerstitial fibrosis...
Bovine casein is considered as an important source of many bioactive peptides (BAPs), which can also be produced <italic>via</italic> not olny<italic> in vitro</italic> simulated but <italic>in vivo </italic>gastrointestinal hydrolysis.
Goat milk protein can release a variety of bioactive peptides after digestion, while most them are digested into free amino acids or dipeptides via the GI tract. We investigated peptide profiles goat following in vitro gastrointestinal digestion using LC-MS/MS and identified 683 peptides, including 105 DPP-IV inhibitory peptides. Among these ILDKVGINY (IL), derived from β-lactoglobulin, was found to be high content resistance digestion. Herein, we explore effect acid residue substitution at...
Abstract Salidroside is a major phenylethanoid glycoside in Rhodiola rosea L., traditional Chinese medicine, with multiple biological activities. It has been shown that salidroside possesses protective effects for alleviating diabetic renal dysfunction, contrast‐induced‐nephropathy and other kidney diseases. However, the involved molecular mechanism was still not understood well. Herein, we examined of mice Adriamycin (ADR)‐induced nephropathy underlying mechanism. The results showed...
In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer. The could stimulate B-lymphocyte proliferation and reduce TNF-α level. Then, identified bioactive derived hydrolysis using LC-MS/MS. Our results demonstrated that five peptides at cell level was bypass transport. addition, majority RYPLGYL transported through monolayer membrane as an intact form for playing functions. KHPIK FFSDK...
A chitosan/gelatin composite microsphere ( CGMS ) adsorbent prepared by inverse suspension was used as a reactive dye washing agent. Techniques such scanning electron microscopy, X‐ray diffraction analysis, and atomic force microscopy facilitated the evaluation of materials. series experiments were conducted to assess effect variables, i.e. initial pH, temperature, dosage, contact time. The wash‐off effectiveness increased with increase in temperature decrease pH. Results obtained from this...
A rapid pretreatment-free immunochromatographic assay (ICA) was developed for the screen of Escherichia coli O157:H7 (E. O157:H7) in bovine milk. Anti-E. immunoglobins yolk (IgY) conjugated with a core/shell-structured super-paramagnetic Fe3O4/Au composite nanoparticle (GoldMag) and showed high coupling ratio 8 µg IgY mL−1 nanoparticles at pH 8.0. The conditions ICA strips using this conjugate were optimized could be used to measure spiked E. samples detection limit 103 CFU obtained by...
The use of amphoteric chitosan/gelatin composite microspheres (CGMSs) has been studied as an adsorbent for the removal Acid Red 337 (AR337) from wastewater. was characterized by using several methods such scanning electron microscopy and atomic force microscope (AFM). kinetic study performed based on pseudo-first-order, pseudo-second-order, intraparticle diffusion equations. It shown that adsorption process could be described pseudo-second-order equation, suggesting is presumably a...
Free heme is an endogenous danger signal that provokes innate immunity. Active immunity provides a precondition of effective adaptive immune response. However, catabolites, CO, biliverdin and bilirubin trigger immunosuppression. Furthermore, free induces expression oxygenase-1 to increase production bilirubin. As such, can play paradoxical role in What the outcome animal response antigen presence heme? This question remains be explored. Here, we report immunization results rats mice after...
Free heme is an endogenous danger signal to provoke innate immunity. Active immunity a precondition of effective adaptive immune response. However, catabolites, CO, biliverdin and bilirubin trigger immunosuppression. Furthermore, free induces the expression oxygenase-1 reinforce production bilirubin. As such, can drive two antagonistic mechanisms affect What outcome animal response antigen in presence heme? The question remains be explored. Here we report immunization results by...
Abstract βlactoglobulin (β-LG) is an important whey protein because of its high ability to bind hydrophobic small molecules. Phlorizin a kind apple polyphenol. The interaction mechanism between phlorizin and β-lactoglobulin in the milk system effect on β-LG after thermal processing are still unclear. Therefore, structural antigenic changes compound under different was studied. Firstly, binding mode simulated by molecular docking, conformation were explored spectroscopy. Indirect ELISA used...