Xuefeng Chen

ORCID: 0000-0003-1510-9247
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About
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Research Areas
  • Fungal Biology and Applications
  • Polysaccharides and Plant Cell Walls
  • Phytochemicals and Antioxidant Activities
  • Diet, Metabolism, and Disease
  • Organ Transplantation Techniques and Outcomes
  • Neutropenia and Cancer Infections
  • Cardiac Arrhythmias and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Mycorrhizal Fungi and Plant Interactions
  • Diabetes Management and Research
  • Antibiotics Pharmacokinetics and Efficacy
  • Lipoproteins and Cardiovascular Health
  • Microbial Metabolites in Food Biotechnology
  • Diet and metabolism studies
  • Medical Research and Treatments
  • Diabetes and associated disorders
  • Antibiotic Resistance in Bacteria
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiovascular Health and Risk Factors
  • Liver Disease Diagnosis and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Clinical Nutrition and Gastroenterology
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Chronic Kidney Disease and Diabetes

West China Hospital of Sichuan University
2022-2025

Shaoxing University
2025

Sichuan University
2022-2025

Hebei General Hospital
2021-2025

Shaanxi Normal University
2020-2025

Shaoxing People's Hospital
2025

Shaanxi University of Science and Technology
2017-2024

Children's Hospital of Zhejiang University
2012-2024

Fuwai Yunnan Cardiovascular Hospital
2023

Soochow University
2023

Pleurotus eryngii (PE) is an edible mushroom with high nutritional value. polysaccharides (PEPs) are one of the main active ingredients and manifest a great variety biological activities. This study mainly focused on chemical characterization activities PEPs, which were separated into two fractions (named WPS P-1). dominated by β-glycosidic bonds contains α-glycosidic bonds, P-1 only bonds. The molecular weights 4.5 × 105 Da 2.2 104 Da. result GC indicated that composed rhamnose, arabinose,...

10.3390/molecules27207140 article EN cc-by Molecules 2022-10-21

Objective: With the rising prevalence of diabetes worldwide, increased attention is focused on natural drug candidates that can treat with high efficacy but without undesired side effects. Lentinus edodes an edible and medicinal fungus, whose polysaccharides are one main components have been reported to hypoglycemic ability. However, detailed underlying mechanism still unknown. In this study, we extracted prepared a novel polysaccharide from edodes, which was named LNT-1. Methods: The aim...

10.1039/d1fo03487a article EN Food & Function 2022-01-01

To examine the prevalence of refractive error and some associated factors in Chinese preschool children.The Jinshan District Eye Study was a school-based survey eye health large sample 4- to 6-year-olds attending kindergartens from May 2013 December Shanghai. Refractive measured using an autorefractor under noncycloplegic conditions. Axial length (AL) with ocular biometry system. In addition, body height weight were also recorded.A total 7,166 children successfully completed their refraction...

10.1097/icl.0000000000000555 article EN cc-by-nc-nd Eye & Contact Lens Science & Clinical Practice 2018-09-28

This study evaluated the hypoglycemic effect of Auricularia auricula polysaccharides (AAPs) on streptozotocin-induced type 2 diabetes mellitus (T2DM) mice using metabolomic analysis. The results fasting blood glucose, oral glucose tolerance test, serum insulin level, Homeostatic Model Assessment Insulin Resistance index, TC, TG, HDL-C, LDL-C, and histopathological observation demonstrated that 200 mg per kg body weight day AAP led to significant activities. metabolic profile was...

10.1039/d1fo02022f article EN Food & Function 2021-01-01

Recent studies have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors play a beneficial role for normoglycemic patients with heart failure (HF). However, the underlying mechanism remains largely unexplored. In present study, we aimed to investigate cardioprotective effect of SGLT2 in rabbit model chronic (CHF) and its potential was also explored. A total 24 male New Zealand white rabbits were randomly divided into sham group, HF perindopril dapagliflozin (DAPA) group. The CHF...

10.3389/fphar.2022.873108 article EN cc-by Frontiers in Pharmacology 2022-05-13

Objective To study the effect of Dapagliflozin on ferroptosis in rabbits with chronic heart failure and to reveal its possible mechanism. Methods Nine healthy adult male New Zealand white were randomly divided into Sham group (only thorax opening was performed group, no ascending aorta circumferential ligation performed), Heart (HF HF establish animal model failure), (DAPA after rabbit successfully made DAPA group). given by force-feeding method. Echocardiography used assess cardiac...

10.1371/journal.pone.0317295 article EN cc-by PLoS ONE 2025-01-28

This study was designed to develop a probiotic Eurotium cristatum-fermented soybean powder (EFSP), and its chemical composition of main nutrients volatile components, laxative abilities against diphenoxylate-induced constipation in...

10.1039/d4fo06067a article EN Food & Function 2025-01-01

Identifying the risk factors for perioperative myocardial injury/infarction (PMI) is critical to prevent postoperative adverse cardiovascular events. However, whether reducing preoperative LDL-C can mitigate of PMI remains unclear. We therefore investigated effect level in patients with stable angina pectoris (SAP) or unstable (UAP) on after elective percutaneous coronary intervention (PCI). Patients SAP UAP who received PCI from January 2021 June 2023 at one two institutions (Hebei...

10.2147/ijgm.s508529 article EN cc-by-nc International Journal of General Medicine 2025-02-01

Mycotoxins are among the primary factors compromising food quality and safety. To investigate mycotoxin contamination, microbial diversity, functional profiles in maize across distinct geographic regions, this study analyzed samples from Xuanwei, Fuyuan, Zhanyi. Mycotoxin concentrations were quantified through standardized assays, while community structures characterized using metagenomics sequencing. Metabolic pathways, genes, enzymatic activities systematically annotated with KEGG, eggNOG,...

10.3390/foods14081378 article EN cc-by Foods 2025-04-16

Objective: Diabetic ketoacidosis (DKA) stands as the most common acute hyperglycaemic complication with a relatively high mortality rate among children diagnosed type 1 diabetes (T1D). Previous studies have shed light on gut dysbiosis in newly-onset T1D children, but research targeting microbiota and microbial metabolites patients DKA remains scarce. Methods: Shotgun metagenomic analysis was conducted fecal samples from 96 newly including 32 who presented upon admission. Short-chain fatty...

10.1101/2025.04.22.650027 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2025-04-23

This study aimed to assess the effects of hydromorphone as an adjuvant ropivacaine serratus anterior plane block (SAPB) on postoperative analgesia and inflammatory responses in patients undergoing video-assisted thoracoscopic surgery (VATS). was a prospective, randomized, double-blind clinical trial. A total 120 lung cancer patients, aged 20-75 years, with American Society Anesthesiologists classification I or II body mass index 18-28 kg/m², were randomly assigned three groups: combined SAPB...

10.1186/s12871-025-03101-2 article EN cc-by-nc-nd BMC Anesthesiology 2025-05-10

Hypertension is a global health concern, and antihypertensive medications are vital for its management. This study examined evolving trends in medication usage among adults with hypertension from 1999 to 2020. Data ten National Health Nutrition Examination Survey (NHANES) survey cycles were obtained aged 18 years older hypertension. The analysed demographic, drug classification, demographic variables. All statistical analyses, including logistic regression, used assess trends. Among 18,221...

10.1080/08037051.2025.2506081 article EN cc-by Blood Pressure 2025-05-17
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