Methicillin-resistant

Abstract Introduction The leaves of Annona muricata L., known as “soursop” or “ sirsak ” in Indonesia, are used traditionally for cancer treatment. However, the bioactive components remain largely unidentified. Objective This study untargeted liquid chromatography–tandem mass spectrometry (LC‐MS/MS)‐based metabolomics to identify potential cytotoxic compounds A. leaf extracts on MCF‐7 breast cells vitro. Methods were macerated with water, 99% ethanol, and aqueous mixtures containing 30%,...

Andrographis paniculata, widely used as an antidiabetic in Indonesian traditional medicines (jamu), contains chemical compounds whose concentration is related to its therapeutic effects. The of solvents for extraction will also affect the number extracted. Therefore, a quality control method needed ensure consistency quantifying these A. paniculata improve application. High-performance liquid chromatography fingerprint analysis combined with chemometrics was evaluate extracts from different...

A glassy carbon electrode modified with electrochemically reduced graphene oxide (ErGO) and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) was developed for uric acid determination dopamine as interference in artificial saliva. The electrochemical performance of the fabricated studied using both techniques cyclic voltammetry (CV) differential pulse (DPV), under optimized conditions. Using DPV, sensor based on ErGO/PEDOT:PSS GCE displayed a linear relationship...

A highly selective electrochemical sensor based on a molecularly imprinted polymer (MIP) to be developed for uric acid detection in the presence of dopamine as an interference molecule was demonstrated this study. This non-enzymatic by electropolymerizing poly-pyrrole onto composite electrochemically reduced graphene oxide (ErGO) and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) glassy carbon electrode (GCE) give MIP/ErGO/PEDOT:PSS electrodes. The structural properties,...

Bisphenol A (BPA) is increasingly released into water, soil, and air, becoming an environmental pollutant. Since BPA persistent in the environment, it remains there for a considerable amount of time allows bioaccumulation, potentially affecting ecosystems human health. For that reason, detection environment essential. In this study, we develop electrochemical sensor simple rapid water environment. The was developed using glassy carbon electrode (GCE) modified with conductive materials....

This study aims to find the biomarkers for antibacterial activity in Mahapengiri citronella grass (Cymbopogon nardus L.). They were determined by comparing compounds contained between each sample of essential oil and extract thoroughly using a Gas Chromatography-Mass Spectrometry (GC-MS)-based metabolomic approach. Essential was obtained hydrodistillation with without sonication pre-treatment, steam distillation. Citronella through maceration n-hexane ethyl acetate. The samples’ tested broth...

The solubility of stearic acid in ethanol, methanol, ethyl acetate, and acetone has been measured gravimetrically at various temperatures ranging from 301 to 313 K atmospheric condition. acetate was found be the highest, followed by methanol. All experimental data were correlated using non-ideal solution models, namely, modified Apelblat Buchowski equations. calculated results agreed well with data.

<span lang="EN-US">Soil color is a crucial indicator in soil science and agriculture; it provides information about properties conditions. Typically, surveyors determine by visually comparing the samples to Munsell Soil Color Chart (MSCC). However, accuracy of this method can be influenced lighting conditions observer's subjectivity, leading potential inconsistencies. This study introduces portable sensor device designed improve consistency determining its MSCC notation compared...

Abstract Noni fruit ( Morinda citrifolia ) has been traditionally used in medicine for its potential health benefits, including hypertension prevention, cancer treatment, and more. However, there is a notable lack of standardization raw materials derived from noni plants use herbal medicine. To address this gap, it crucial to identify cultivate superior varieties. Cianjur Regency, prominent agricultural area West Java, known cultivation by local farmers. This study, conducted 2021 aimed...

Andrographis paniculata is known as the king of bitter and it has been widely used a medicinal plant. The properties A. are generally determined by metabolite composition, which may be influenced several factors, one part plant extracted. objectives this research to identify putatively composition stem leaves extracts using LC-MS/MS classify them PCA. samples were separated extracted sonication with 70% ethanol. A total 31 compounds identified. All identified in extracts, only differed their...

The potential application of Xylocarpus granatum, a mangrove species, as traditional medicine has been widely linked to its high secondary metabolite and antioxidant contents. However, few studies have reported identify classify active metabolites responsible for such excellent biological activities. Therefore, the aim this work was determine activity, profiles, predict acting antioxidants in X. granatum extract using gas chromatography-mass spectrometry (GC-MS)-based metabolomics approach....

Solubility data of isoniazid in supercritical carbon dioxide are important selecting the most appropriate methods for pharmaceutical material processing, such as micronization or production composites. The solubility was measured using a dynamic analytical method at temperatures (308, 311, and 313) K pressures ranging from (13.0 to 18.5) MPa. result showed that increased with increase pressure an isothermal condition it also temperature. experimental were correlated Chrastil Mendez-Santiago...

The solubility of pyridine-4-carbohydrazide (isoniazid) in ethanol, methanol, ethyl acetate, and acetone has been measured gravimetrically at various temperatures ranging from (301 to 313) K atmospheric pressure. Isoniazid is most soluble followed by acetone, acetate a temperature up 308 K. At higher than K, isoniazid acetone. experimental data were correlated using the modified Apelblat equation.

Curcuma aeruginosa is known as one of the components herbal medicine with various biological activities. This research aims to identify metabolites content C. related their activities using LC-MS fingerprint combined chemometrics. from 3 areas in Java were collected and macerated ethanol then analyzed LC-MS. Along this analysis, antioxidant activity all samples was determined CUPRAC method, toxicity Brine Shrimp Lethality Test (BSLT), chemometric method used Principle Component Analysis...

Jamu is an Indonesia herbal medicine made from natural materials such as roots, leaves, fruits, and animals. The purpose of this research to develop a classification system for jamu efficacy based on the composition plants using Support Vector Machine (SVM) implement k-means clustering algorithm feature selection method. result study was compared previous that SVM method without selection. This used variances evaluate results clustering. total 3138 data herbs 465 plant species were grouped...