A5074642385- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Advanced Sensor and Energy Harvesting Materials
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- biodegradable polymer synthesis and properties
- Electrohydrodynamics and Fluid Dynamics
- Cardiac and Coronary Surgery Techniques
- Conducting polymers and applications
- Additive Manufacturing and 3D Printing Technologies
- Aortic Disease and Treatment Approaches
- Nerve injury and regeneration
- 3D Printing in Biomedical Research
- Reconstructive Surgery and Microvascular Techniques
- Wound Healing and Treatments
- RNA Interference and Gene Delivery
- Bee Products Chemical Analysis
- Immune cells in cancer
- Cell Adhesion Molecules Research
- Dental Implant Techniques and Outcomes
- Mesenchymal stem cell research
- Infectious Aortic and Vascular Conditions
- Essential Oils and Antimicrobial Activity
University of Memphis
2016-2025
Case Western Reserve University
2016
Cornell University
2016
University of Tennessee Health Science Center
2016
Memphis Health Center
2014
Virginia Commonwealth University
2005-2014
University of Richmond
2011-2013
Donghua University
2012
Virginia Commonwealth University Medical Center
2012
VCU Massey Comprehensive Cancer Center
2012
Electrospinning is a fabrication process that uses an electric field to control the deposition of polymer fibers onto target substrate. This electrostatic processing strategy can be used fabricate fibrous mats composed fiber diameters ranging from several microns down 100 nm or less. In this study, we describe how electrospinning adapted produce tissue-engineering scaffolds collagen nanofibers. Optimizing conditions for calfskin type I produced matrix exhibited 67 banding pattern...
The first results of electrospinning fibrinogen nanofibers for use as a tissue-engineering scaffold, wound dressing, or hemostatic bandage are reported. Structures composed fibers with an average diameter 80−700 nm were electrospun from solutions human bovine fraction I dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol and minimal essential medium (Earle's salts). In summary, the process is simple efficient technique fabrication 3D structures fibers, would be present physiologic environment.
Natural polymers such as collagens, elastin, and fibrinogen make up much of the body’s native extracellular matrix (ECM). This ECM provides structure mechanical integrity to tissues, well communicating with cellular components it supports help facilitate regulate daily processes wound healing. An ideal tissue engineering scaffold would not only replicate this ECM, but also many functions that performs. In past decade, process electrospinning has proven effective in creating non-woven...
Poly(glycolic acid) (PGA) has long been a popular polymer in the tissue engineering field. PGA possesses many favorable properties such as biocompatibility, bioabsorbability, and tensile strength. The traditional fiber formation techniques of melt extrusion cold-drawing are generally limited to fibers 10–12 μm diameter. Electrostatic spinning, or electrospinning, is an attractive approach for production much smaller diameter which interest scaffolds. We demonstrate ability control function...
Electrospinning is a process that creates nanofibers through an electrically charged jet of polymer solution or melt. This technique applicable to virtually every soluble fusible and capable spinning fibers in variety shapes sizes with wide range properties be used broad biomedical industrial applications. requires very simple economical setup but intricate depends on several molecular, processing, technical parameters. article reviews information the three stages electrospinning (i.e.,...
Fully (99+ %) hydrolyzed poly(vinyl alcohol) (PVA) was electrospun from water using Triton X-100 surfactant to lower the surface tension. The diameter of PVA fibers ranged 100 700 nm. Treatment fiber mats with methanol for 8 h stabilized against disintegration in contact water. In addition, showed increased mechanical strength due crystallinity following post-spinning treatment methanol. We suggest that serves increase degree crystallinity, and hence number physical cross-links fibers. This...
In trying to assess the structural integrity of electrospun type II collagen scaffolds, a modified but new technique for cross-linking has been developed. Carbodiimides have previously used cross-link in gels and lyophilized native tissue specimens had not mats until recently. This agent, particular 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC), is extreme interest, especially tissue-engineered scaffolds composed specifically polymers (e.g., collagen), because it...
A suitable technique for articular cartilage repair and replacement is necessitated by inadequacies of current methods. Electrospinning has potential in producing scaffolds with fiber diameters the range native extracellular matrix. Chondrocytes seeded onto such may prefer this environment differentiation proliferation, thus approaching functional tissue. Scaffolds collagen type II were created an electrospinning technique. Individual scaffold specimens prepared evaluated as uncross-linked,...
An electrospun cardiovascular graft composed of polydioxanone (PDO) and elastin has been designed fabricated with mechanical properties to more closely match those native arterial tissue, while remaining conducive tissue regeneration. PDO was chosen provide integrity the prosthetic, provides elasticity bioactivity (to promote regeneration in vitro/in situ). It is elastic nature that dominates low-strain response vessel blood flow prevents pulsatile energy from being dissipated as heat....
Abstract While electrospinning had seen intermittent use in the textile industry from early twentieth century, it took explosion of field tissue engineering, and its pursuit biomimetic extracellular matrix (ECM) structures, to create an renaissance. Over past decade, a growing number researchers engineering community have embraced as polymer processing technique that effectively routinely produces non‐woven structures nanoscale fibers (sizes 80 nm 1.5 µm). These nanofibers are physiological...
Abstract Poly(glycolic acid) (PGA) has a long history as bioresorbable polymer. Its biocompatibility is widely accepted, yet PGA often rejected soft‐tissue scaffold because of fibrous encapsulation. The goal this study was to improve the by producing scaffolds composed small‐diameter fibers through electrospinning and subjecting these concentrated hydrochloric acid (HCL) pretreatment. theory that will elicit reduced immune response HCl treatment cellular interactions. Scaffolds were...