A5063282556- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Enzyme Catalysis and Immobilization
- Enzyme Production and Characterization
- Amino Acid Enzymes and Metabolism
- Protein Hydrolysis and Bioactive Peptides
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Biochemical and Molecular Research
- Conducting polymers and applications
- Digestive system and related health
- RNA and protein synthesis mechanisms
- Biomedical Research and Pathophysiology
- Polyamine Metabolism and Applications
- Phytase and its Applications
- Supramolecular Self-Assembly in Materials
- GABA and Rice Research
- Natural product bioactivities and synthesis
- Plant tissue culture and regeneration
- Biochemical Analysis and Sensing Techniques
- Pancreatic function and diabetes
- Advanced Photocatalysis Techniques
- Ga2O3 and related materials
- Folate and B Vitamins Research
- Electrochemical sensors and biosensors
Ho Chi Minh City University of Science
2025
Nanjing Tech University
2014-2025
The Synergetic Innovation Center for Advanced Materials
2020-2025
Vietnam National University Ho Chi Minh City
2025
Jilin University
2025
Tianjin Institute of Industrial Biotechnology
2025
Chinese Academy of Sciences
2025
Shenyang Agricultural University
2009-2020
Xi'an Technological University
2020
Shenyang University of Technology
2013
Cadaverine, a natural polyamine with multiple bioactivities that is widely distributed in prokaryotes and eukaryotes, becoming an important industrial chemical. Cadaverine exhibits broad prospects for various applications, especially as monomer bio-based polyamides. Cadaverine-based polyamide PA 5X has application owing to its environmentally friendly characteristics exceptional performance water absorption dimensional stability. In this review, we summarize recent findings on the...
Stevioside and rebaudioside A are the chief diterpene glycosides present in leaves of Stevia rebaudiana. Rebaudioside imparts a desirable sweet taste, while stevioside produces residual bitter aftertaste. Enzymatic synthesis from can increase ratio to steviol glycoside products, providing conceivable strategy improve organoleptic properties products. Here, we demonstrate efficient conversion by coupling activities recombinant UDP-glucosyltransferase UGT76G1 S. rebaudiana sucrose synthase...
Design the adenosine phosphate hydrolysis (APH) pathway multienzyme cascade system for biosynthesis of nicotinamide mononucleotide (NMN) in vitro .
Abstract Okara, a renewable biomass resource, is promising fermentative raw material for the bio-production of value-added chemicals due to its abundance and low-costs. we developed process enzymatic hydrolysis okara, then engineered Bacillus subtilis utilize mixed sugars produce acetoin in okara without addition supplemental nitrogen source. Okara was initially hydrolyzed with cellulase, β-glucosidase, pectinase obtain hydrolysate containing (32.78 ± 0.23 g/L glucose, 1.43 0.064 arabinose,...
Abstract Background Even though tofu is a traditional Chinese food loved by Asian people the wastewater generated during production of can pollute environment, and treatment this increase operating cost plant. In study, nattokinase could be achieved using nitrogen source in processing (TPW) instead medium. This meets need for low-cost fermentation at same time addresses environmental pollution concerns caused wastewater. Bacillus subtilis 13,932 is, high yielding strain nattokinase, which...
The fabrication of a hybrid UCMPs/RGO based photodetector with enhanced device performance under infrared light illumination.
Wastewater-based epidemiology (WBE) represents a powerful technique for quantifying the attenuation characteristics and consumption of pharmaceuticals. In addition to WBE, no further methods have been developed assess wastewater stability related antidepressants (ADs). this study, biodegradability, solubility, adsorption or partition 66 ADs were objectively scored according relevant guidelines Organisation Economic Cooperation Development. An assessment framework MSSL-RealFormer...
Nattokinase is an alkaline serine protease with potent thrombolytic activity. Due to its safety profile, low cost, and ease of oral administration, it has gained significant attention for therapeutic applications. To meet the demand cost-effective production nattokinase via fermentation, this study utilized renewable biomass resources-glycerol okara-as raw materials production. A metabolic pathway efficient glycerol utilization in Bacillus subtilis 13,932 was engineered using genetic...
Fermented foods have gained immense popularity in recent years due to their distinct flavor profile. Given the increasing demand, there is a growing focus on optimizing nutritional quality while also reducing costs. In this study, using novel approach, hemp seed meal was utilized as solid fermentation substrate produce nattokinase (NK). Using combination of one-factor-at-a-time experiments, Plackett–Burman design, and Box–Behnken optimal conditions Bacillus subtilis 13932 (NK-producing...
Abstract Acetoin, a versatile platform chemical and popular food additive, poses challenge to the biosafety strain Bacillus subtilis when produced in high concentrations due its intrinsic toxicity. Incorporating PHB synthesis pathway into 168 has been shown significantly enhance strain’s acetoin tolerance. This study aims elucidate molecular mechanisms underlying response of B. 168- phaCBA stress, employing transcriptomic metabolomic analyses. Acetoin stress induces fatty acid degradation...
Phospholipase D (PLD)-mediated transphosphatidylation of phosphatidylcholine (PC) in a biphasic system was limited by the hydrolysis reaction. A can produce large amount water. To solve this problem, microaqueous water-immiscible organic solvent used for first time bioconversion phosphatidylserine (PS). The among 40 µmol PC, 800 l-serine, and 0.17 U/mL PLD 2.133 mL butyl acetate with 6.25% water (V/V) conducted at trans-phosphatidylation rate 88% (mol/mol), no hydrolytic reaction observed....
A highly sensitive electrochemical sensor for the detection of mercury(ii) ions (Hg2+) was developed by using a three dimensional ordered macroporous polyaniline-platinum (3DOM PANI-Pt) composite film as sensing platform. 3DOM PANI-Pt realized co-deposition Pt nanoparticles and PANI into sacrificed silica template through redox reaction involving monomer aniline (AN) PtCl6 2-. The G-rich oligonucleotide strand functionalized Au nanoparticle employed Hg2+-mediated structural switch to enhance...
In this study, we investigated the protective effect of Nattokinase (NK), most active ingredient in natto used for healthcare, on dextran sulfate sodium (DSS)-induced chronic colitis and unraveled potential mechanisms. NK dramatically attenuated clinical symptoms pathological damage DSS-induced colitis. also inhibited proinflammatory cytokines production colonic tissues. Mucosal integrity was maintained by NK. Moreover, nattokinase reversed decline bacteria community diversity intestinal...
Abstract l ‐Ornithine is an intermediate of the ‐arginine biosynthetic pathway in Corynebacterium glutamicum . The effect ornithine acetyltransferase (OATase; ArgJ) on ‐ornithine production was investigated, and C. 1006 engineered to overproduce as a major product by inactivating regulatory repressor argR gene overexpressing argJ gene. A genome sequence analysis indicated that argF encoding carbamoyltransferase mutated, resulting accumulation certain amount (20.5 g/L). assays using crude...
Abstract Nattokinase from fermentation has recently gained more attention due to its beneficial effects on cardiovascular system. However, the instability of free nattokinase limits application. The aim study was develop a spray‐drying microencapsulation process obtain powder with high activity, quality, and strong storage stability. Hence, by spray drying optimized. Experiments single‐factor response surface methodology were used assess comprehensive scores activities. According results,...