A5100360317- Metabolomics and Mass Spectrometry Studies
- Natural product bioactivities and synthesis
- Nanoplatforms for cancer theranostics
- Plant-based Medicinal Research
- Traditional Chinese Medicine Analysis
- Gut microbiota and health
- Hormonal and reproductive studies
- Sperm and Testicular Function
- Diet and metabolism studies
- Natural Compounds in Disease Treatment
- Phytochemistry and Biological Activities
- Sexual function and dysfunction studies
- Drug-Induced Hepatotoxicity and Protection
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects of Natural Compounds
- Photodynamic Therapy Research Studies
- Crystallization and Solubility Studies
- Bioactive Natural Diterpenoids Research
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Luminescence and Fluorescent Materials
- Urinary Bladder and Prostate Research
- Adipose Tissue and Metabolism
- Membrane Separation Technologies
- Genomics, phytochemicals, and oxidative stress
Nanjing Tech University
2016-2025
China Agricultural University
2022-2025
Tianjin University of Traditional Chinese Medicine
2024-2025
Tianjin Medical University General Hospital
2024
Zhongnan Hospital of Wuhan University
2024
Wuhan University
2024
State Key Laboratory of Chemical Engineering
2023
East China University of Science and Technology
2023
Hubei University
2022
Zhejiang University
2022
Ti3C2 MXene is a new two-dimensional material exhibiting variety of novel properties including good photothermal effect, and the capability for multimodal tumor therapy in urgent need development. Herein, ultrathin nanosheets (∼100 nm) have been synthesized by supplying additive Al3+ to avoid Al loss employed as photothermal/photodynamic agent cancer therapy. The as-obtained exhibit outstanding mass extinction coefficient (28.6 Lg–1 cm–1 at 808 nm), superior conversion efficiency (∼58.3%),...
Developing smart photosensitizers sensitively responding to tumor-specific signals for reduced side effects and enhanced anticancer efficacy is a major challenge tumor phototherapy. Herein, pH-sensitive photosensitizer has been synthesized through introducing receptor (dimethylaminophenyl unit) onto the aza-BODIPY core (abbreviated as NAB). Through enveloping hydrophobic NAB with amphiphilic DSPE-mPEG2000, nanoparticles (NPs, diameter ∼ 30 nm) strong near-infrared absorption (∼792 are...
Cadmium (Cd) is a toxic pollutant with high nephrotoxicity in the agricultural environment. Resveratrol has been found to have renoprotective effect but underlying mechanisms of this not yet fully elucidated. The aim study illustrate antagonism resveratrol against Cd-induced nephrotoxicity. A total 80 birds were divided randomly into 4 groups and treated via diet for 90 days as follows: control group (Con); 400 mg kg-1 (Resv); 140 Cd (Cd 140); + Resv). It was observed that treatment...
Novel photosensitizers have been developed with high <sup>1</sup>O<sub>2</sub> quantum yields and strong fluorescence for cancer diagnosis PDT.
Improving the deep-tissue phototherapy (PDT) efficiency in near-infrared (NIR) region has become one of major challenges clinics for cancer treatment.
A NIR D–A–D structure of a ferrocene flanked diketopyrrolopyrrole derivative with tetracyanobutadiene unit is synthesized for photoacoustic imaging-guided amplifying photothermal therapy.
Abstract Osteosarcoma is the most common high-grade human primary malignant bone sarcoma with lower survival in past decades. Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens , has been proved to possess potent anti-cancer effects. However, its potential mechanism still remains not fully clear nowadays. In this study, we investigated anticancer effect of oridonin on osteosarcoma and illuminated underlying mechanisms. vitro, inhibited cell viability various cells. We...
The development of potent non-toxic chemotherapeutic drugs against castration resistant prostate cancer (CRPC) remains a major challenge. Corosolic acid (CA), natural triterpenoid, has anti-cancer activity with limited side effects. However, CA anti-prostate activities and mechanisms, particularly in CRPC, are not clearly understood. In this study, we investigated anti-tumor ability human CRPC its mechanism action.The cell apoptosis proliferation effects were evaluated via MTT detection,...
The gut microbiota and liver cancer have a complex interaction. However, the role of microbiome in tumor initiation remains unknown. Herein, was induced using hydrodynamic transfection oncogenes to explore tumorigenesis mice. Gut depletion promoted but not progression. Elevated sterol regulatory element-binding protein 2 (SREBP2) observed mice with flora disequilibrium. Pharmacological inhibition SREBP2 or Srebf2 RNA interference attenuated mouse under Furthermore, impaired tryptophan...
Objective We aimed to examine the relationship between weight-adjusted waist index (WWI) and obstructive sleep apnea (OSA), a condition often caused by obesity, which remains unclear. Methods In this cross-sectional study, we analyzed data from National Health Nutrition Examination Survey among adults in United States (US) aged 20 65 years, covering periods 2005 2008 2015 2018. The study included 8278 participants; used multivariate logistic regression, restricted cubic splines, subgroup...
Expression of double-stranded RNAs in plastids offers great potential for the efficient control chewing insects. However, many insect pests do not consume plant tissue but rather feed on host by sucking sap from vascular system. Whether or plastid-mediated RNA interference (RNAi) can be employed to sap-sucking insects is unknown. Here, we show that five species hemipteran acquire plastid upon feeding plants. We generated both nuclear transgenic and transplastomic tobacco plants expressing...