Junmei Xu

ORCID: 0000-0003-0925-0789
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About
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Research Areas
  • Anesthesia and Neurotoxicity Research
  • Thyroid Cancer Diagnosis and Treatment
  • Cardiac Ischemia and Reperfusion
  • Anesthesia and Pain Management
  • Ultrasound and Hyperthermia Applications
  • Anesthesia and Sedative Agents
  • Ultrasound Imaging and Elastography
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pain Mechanisms and Treatments
  • Thyroid and Parathyroid Surgery
  • COVID-19 Clinical Research Studies
  • Intensive Care Unit Cognitive Disorders
  • Boron Compounds in Chemistry
  • Airway Management and Intubation Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Spine and Intervertebral Disc Pathology
  • Head and Neck Anomalies
  • Long-Term Effects of COVID-19
  • Cancer, Stress, Anesthesia, and Immune Response
  • Mitochondrial Function and Pathology
  • Hemodynamic Monitoring and Therapy
  • Cardiac Arrest and Resuscitation
  • COVID-19 and Mental Health
  • COVID-19 and healthcare impacts
  • Radiomics and Machine Learning in Medical Imaging

Central South University
2016-2025

Second Xiangya Hospital of Central South University
2016-2025

University of Pennsylvania
2024

Shanghai Tenth People's Hospital
2012-2020

Capital Medical University
2011-2020

Tongren Hospital
2020

Shanghai Jiao Tong University
2020

Beijing Friendship Hospital
2020

Tongji University
2012-2017

XinHua Hospital
2017

Objective Virtual touch tissue quantification (VTQ) of acoustic radiation force impulse (ARFI) is a new quantitative technique to measure stiffness. The study was aimed assess the usefulness VTQ in diagnosis thyroid nodules. Methods 173 pathologically proven nodules 142 patients were included and all examined by conventional ultrasound (US), elasticity imaging (EI) ARFI. stiffness for expressed as shear wave velocity (SWV) (m/s). Receiver-operating characteristic curve (ROC) analyses...

10.1371/journal.pone.0049094 article EN cc-by PLoS ONE 2012-11-13

To evaluate conventional ultrasonography (US), US elasticity imaging (EI), and acoustic radiation force impulse (ARFI) in thyroid nodule malignancy prediction.This prospective study was institutional review board approved; informed consent obtained. Study included 375 patients (mean age, 51 years; range, 18-75 years) with 441 pathologically proven nodules. In 281 women 50 94 men 53 18-74 years), US, EI, Virtual Touch tissue (VTi; Siemens, Mountain View, Calif), quantification (VTq; Siemens)...

10.1148/radiol.14132438 article EN Radiology 2014-04-01

Asymptomatic and symptomatic patients may transmit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but their clinical features immune responses remain largely unclear. We aimed to characterise the of asymptomatic infected with SARS-CoV-2.We collected clinical, laboratory epidemiological records hospitalised in a field hospital Wuhan. performed qualitative detection anti-SARS-CoV-2 immunoglobulin M (IgM) G (IgG) using archived blood samples.Of 214 SARS-CoV-2, 26 (12%) were at...

10.1002/cti2.1182 article EN cc-by Clinical & Translational Immunology 2020-01-01

Abstract This prospective study of comparing transperineal prostate biopsy (TPBx) with transrectal (TRBx) was aimed to provide evidence for clinicians select the appropriate approach under different conditions. TPBx (n = 173) and TRBx 166) were performed randomly 339 patients who suspicious cancer (PCa). The detection rate (CDR), complication rate, visual analogue scale (VAS) score, most painful procedure, number repeated additional anesthesia operating time (starting from lying down on...

10.1038/srep16089 article EN cc-by Scientific Reports 2015-11-03

Temporary COVID-19 specialty hospitals proved to be useful in the control of an infectious crisis a large epicenter, and hopefully this approach provides blueprint for management future epidemics or pandemics.

10.1097/aln.0000000000003299 article EN other-oa Anesthesiology 2020-03-20

Background: The pathogenic role of brain derived neurotrophic factor (BDNF) in the incisional pain is poorly understood. present study explores BDNF incision-induced hypersensitivity. Methods: A longitudinal incision was made one plantar hind paw isoflurane-anesthetized rats. Dorsal root ganglias (DRG) and spinal cords were removed at various postoperative times (1–72 h). Expression pattern determined by immunohistochemistry double-labeling immunofluorescence. Lidocaine-induced blockade...

10.1186/1744-8069-4-27 article EN cc-by-nc Molecular Pain 2008-01-01

Objectives- Acoustic radiation force impulse elastography is a newly developed ultrasound elasticity imaging technique that included both Virtual Touch tissue quantification and (VTI; Siemens Medical Solutions, Mountain View, CA). This study aimed to evaluate the usefulness of VTI in differentiating malignant from benign thyroid nodules. Methods- 192 consecutive patients with nodules (n = 219) who underwent surgery for compressive symptoms or suspicion malignancy. Tissue stiffness on was...

10.7863/ultra.33.4.585 article EN Journal of Ultrasound in Medicine 2014-03-21

Reperfusion injury is tissue damage caused by the re-supply of blood following a period ischemia in tissues. Intestinal ischemia-reperfusion (IRI) an extremely common clinical event associated with distant organ injury. The intestine serves as initial multi-system dysfunction syndrome. It important to identify method protect against IRI, it key factor morbidity and mortality patients. In present study, protective effects pretreatment dexmedetomidine hydrochloride were investigated. Rats...

10.3892/etm.2013.1317 article EN Experimental and Therapeutic Medicine 2013-09-26

To evaluate the therapeutic efficacy and safety of ultrasound-guided percutaneous bipolar radiofrequency ablation (BRFA) benign thyroid nodules by comparison with a matched untreated control group.The in 35 patients who were subjected to single session BRFA (Group A) for compared those B) nodules. The nature all was confirmed fine-needle aspiration biopsy (FNAB), had normal functions. performed electrode (CelonProSurge 150-T20) an output power 20 W. Nodule volume, function clinical symptoms...

10.1259/bjr.20150858 article EN British Journal of Radiology 2016-01-22

Purpose . To evaluate the diagnostic performance of ARFI imaging in differentiating between benign and malignant thyroid nodules <1 cm. Materials Methods 173 pathologically proven (77 benign, 96 malignant) 157 patients were included this study. Receiver-operating characteristic curve (ROC) analyses performed to assess conventional ultrasound (US) papillary microcarcinoma (PTMC). The independent risk factors for predicting PTMC evaluated. Results mean SWV value 2.57 ± 0.79 m/s (range:...

10.1155/2014/416969 article EN cc-by BioMed Research International 2014-01-01

Shivering associated with spinal anesthesia during Cesarean delivery is an uncomfortable experience for the parturient, which may also cause adverse effects. In this prospective, randomized, double-blind, placebo-controlled study, we sought to evaluate effect of intrathecal dexmedetomidine, administered as adjunct hyperbaric bupivacaine delivery, on incidence and severity shivering anesthesia. Patients undergoing were randomly allocated three groups 30 patients each. Experimental treatments...

10.1248/bpb.b16-00651 article EN Biological and Pharmaceutical Bulletin 2017-01-01

Diabetic neuropathic pain (DNP) is a common complication associated with diabetes. Currently, its underlying pathomechanism remains unknown. Studies have revealed that the recruitment of blood monocyte-derived macrophages (MDMs) to spinal cord plays pivotal role in different models central nervous system injury. Therefore, present study aimed at exploring infiltration and function MDMs DNP using mice model. Diabetes was induced streptozotocin male A/J mice. Mechanical withdrawal thresholds...

10.1155/2019/7597382 article EN cc-by Journal of Immunology Research 2019-08-26

Objectives. The incidence of fentanyl-induced cough (FIC) during induction general anesthesia varies around 40% and is undesirable. It increases intracranial, intraocular, intra-abdominal pressures. This prospective, randomized, double-blind, placebo-controlled study evaluated the effect dexmedetomidine (DEX) pretreatment on severity FIC. Methods. Altogether 300 patients undergoing elective surgical procedures were randomly allocated into three groups (I, II, III; n = 100) administered...

10.3109/03009734.2011.629749 article EN cc-by Upsala Journal of Medical Sciences 2012-02-15

Endothelial dysfunction induced by oxidative stress and inflammation plays a critical role in the pathogenesis of cardiovascular diseases. The anesthetic sevoflurane confers cytoprotective effects through its anti-inflammatory properties various pathologies such as systemic inflammatory response syndrome ischemic-reperfusion injury but mechanism is unclear. We hypothesized that can protect against tumor necrosis factor (TNF)-α-induced endothelial promoting production endothelium-dependent...

10.1016/j.bbrc.2015.03.126 article EN cc-by-nc-nd Biochemical and Biophysical Research Communications 2015-04-05
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