A5100423618- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Metal Extraction and Bioleaching
- Mycobacterium research and diagnosis
- Extraction and Separation Processes
- Minerals Flotation and Separation Techniques
- Advanced Topics in Algebra
- Cancer Genomics and Diagnostics
- Inflammatory Biomarkers in Disease Prognosis
- Cytomegalovirus and herpesvirus research
- Sepsis Diagnosis and Treatment
- RNA modifications and cancer
- Autophagy in Disease and Therapy
- Cancer, Lipids, and Metabolism
- Vitamin D Research Studies
- Educational Reforms and Innovations
- Hepatocellular Carcinoma Treatment and Prognosis
- Diagnosis and treatment of tuberculosis
- Adipose Tissue and Metabolism
- Long-Term Effects of COVID-19
- Hepatitis C virus research
- COVID-19 and Mental Health
- Immunodeficiency and Autoimmune Disorders
- Algebraic structures and combinatorial models
Second Military Medical University
2019-2025
Shanghai Pudong New Area Gongli Hospital
2019-2025
Jiangsu University
2022-2025
Affiliated Hospital of Jiangsu University
2022-2025
Kunming University of Science and Technology
2018-2025
East China Normal University
2024
Liaoning Shihua University
2024
Simcere Pharmaceutical (China)
2022-2023
Wuhan University
2023
Renmin Hospital of Wuhan University
2023
Background The D-dimer to lymphocyte ratio (DLR), a novel inflammatory biomarker, had been shown be related adverse outcomes in patients with various diseases. However, there was limited research on the relationship between DLR and infectious diseases, particularly those sepsis. Therefore, this study aimed explore association hospital all-cause mortality elderly Methods A total of 1123 admitted intensive care unit (ICU) were included study. categorized into quartiles (Q1-Q4) based their...
Chaperonin containing TCP1 subunit 3 (CCT3) acts as an oncogene in cancers, whereas its role and underlying mechanisms lung adenocarcinoma (LUAD) are poorly understood. This study investigated the clinical relevance function of CCT3 LUAD.Clinical LUAD squamous cell carcinoma (LUSC) was analyzed based on TCGA database. qRT-PCR Western blot were used to detect mRNA protein expression, respectively. CCK8 colony formation performed measure viability. PI PI/Annexin V-FITC assay kit determine...
Recent studies have revealed an increase in the incidence rate of non-alcoholic fatty liver disease-related hepatocellular carcinoma (NAFLD-HCC). Furthermore, association Sphingosine 1-phosphate receptor 2 (S1PR2) with various types tumours is identified, and metabolism conjugated bile acids (CBAs) performs essential function onset development HCC. However, CBA S1PR2 NAFLD-HCC unclear.
Hepatocellular carcinoma (HCC) is a commonly diagnosed malignancy worldwide with poor prognosis and high metastasis recurrence rates. Although apatinib has been demonstrated to have potential antitumor activity in multiple solid tumors, the underlying mechanism of HCC treatment remains be elucidated. In present study, were used treat cells transfected or without VEGFR2 overexpression vectors. The proliferation was detected by MTT assay. migration invasion wound healing assay Transwell...
The long-term sequelae of coronavirus disease 2019 (COVID-19) and its recovery have becoming significant public health concerns. Therefore, this study aimed to enhance the limited evidence regarding relationship between sleep quality on long COVID among older population aged 60 years or old. Our included 4,781 COVID-19 patients enrolled from April May 2023, based Peking University Health Cohort. Sleep was assessed using Pittsburgh Quality Index (PSQI) scale. Long evaluated by well-trained...
Soft tissue defects and postoperative wound healing complications related to calcaneus fractures may result in significant morbidity. The aim of this study was investigate whether percutaneous minimally invasive screw internal fixation (PMISIF) can change situation the treatment calcaneal fractures, aimed explore mechanical effects different methods on Sanders type III through finite element analysis. This retrospective analysis focused 83 patients with II from March 2017 2022. Among them,...
The necessity for an effective and sustainable curriculum reform has grown in importance since ice snow sports have advanced so quickly. In order to maximize the development delivery of curriculum, this study investigates integration innovation entrepreneurship education within biomechanics framework. suggests using intelligent systems, like fuzzy c-means (FCM) optimal clustering algorithms, improve assessment advancement instruction from perspective biomechanics. This promotes a...
Background The predictive value of serum uric acid (SUA) for clinical outcomes in patients with sepsis-associated acute kidney injury (SA-AKI) remained unclear. Therefore, this study aimed to evaluate the significance SUA predicting all-cause mortality among critically ill diagnosed SA-AKI. Methods This retrospective examined 483 SA-AKI at Affiliated Hospital Jiangsu University from January 2015 July 2023. primary outcome evaluated was hospital mortality. To assess prognostic SUA, we...
Background Combining PD-1/PD-L1 inhibitors with chemotherapy (PIC) is a standard first-line treatment for advanced non-small cell lung cancer (NSCLC). The addition of bevacizumab to this regimen (PD-1/PD-L1 inhibitors+bevacizumab+chemotherapy [PIBC]) remains controversial regarding its potential enhance antitumor efficacy in clinical practice. This meta-analysis aims compare the effectiveness and safety profiles PIBC PIC. Methods We systematically searched six databases identify eligible...
Objective To evaluate the performance and validate diagnostic value of a nucleotide matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) with analysis process optimized in identification mycobacterium species. Methods The was used for mycobacterial nucleic MALDI-TOF-MS. 108 samples were assessing MALDI-TOF-MS, including 25 reference standards, 37 clinical isolates, BALF, 9 plasmids. BALF 38 patients suspected pulmonary infection collected validation. Clinical...
Axillary lymph node dissection (ALND) can be safely avoided in women with T1 or T2 primary invasive breast cancer (BC) and one to two metastatic sentinel nodes (SLNs). However, cancellation of ALND based solely on SLN biopsy (SLNB) may lead adverse outcomes. Therefore, preoperative assessment LN tumor burden becomes a new focus for ALN status.This study aimed develop validate nomogram incorporating the radiomics score (rad-score) automated ultrasound system (ABUS) other clinicopathological...
Background The aim of this study was to examine the prognostic significance serum albumin-to-creatinine ratio (ACR) in critically ill patients with sepsis. Methods This retrospective analyzed sepsis cases admitted Affiliated Hospital Jiangsu University between January 2015 and November 2023. were divided into four groups based on their ACR upon admission intensive care unit (ICU). Laboratory data collected at time ICU admission, primary outcome measure in-hospital all-cause mortality....
Abstract Infant‐type hemispheric glioma, a new subtype of pediatric high‐grade arises in the cerebral hemispheres. Despite better survival outcomes, treatment infant‐type glioma is still facing challenges. Here, we reported case QKI ‐ ALK fusion, with lung metastasis who achieved complete clinical response after lorlatinib treatment. This typical demonstrated importance appropriate molecularly targeted treatments ‐fused tumors, and may serve as an effective complement to conventional...