Jinyu Zhang

ORCID: 0000-0003-2317-4065
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Adipose Tissue and Metabolism
  • Fatty Acid Research and Health
  • Cancer therapeutics and mechanisms
  • Regulation of Appetite and Obesity
  • Neuroblastoma Research and Treatments
  • Cell death mechanisms and regulation
  • Alzheimer's disease research and treatments
  • RNA Interference and Gene Delivery
  • Neuroscience of respiration and sleep
  • CAR-T cell therapy research
  • Oral and gingival health research
  • Genetic and phenotypic traits in livestock
  • RNA and protein synthesis mechanisms
  • Angiogenesis and VEGF in Cancer
  • Nitric Oxide and Endothelin Effects
  • Lipid metabolism and biosynthesis
  • Biochemical Analysis and Sensing Techniques
  • Phytase and its Applications
  • Nuclear Receptors and Signaling
  • Meat and Animal Product Quality
  • Ruminant Nutrition and Digestive Physiology
  • Seaweed-derived Bioactive Compounds
  • Immune cells in cancer
  • Cytokine Signaling Pathways and Interactions

Southwest Forestry University
2024

Qingdao University
2008-2023

Hebei Medical University
2022-2023

Ollscoil na Gaillimhe – University of Galway
2022-2023

Yangzhou University
2007-2022

Beijing University of Technology
2021

National Natural Science Foundation of China
2016

Shanghai University of Traditional Chinese Medicine
2016

Background Fucoidan is a sulfated polysaccharide derived from brown algae that has been reported to perform multiple biological activities, including antitumor activity. In this study, we examined the influence of crude fucoidan on mouse breast cancer in vitro and vivo. Materials Methods vitro, fluorescent staining, flow cytometry Western blot were performed analyze apoptosis vascular endothelial growth factor (VEGF) expression 4T1 cells. vivo, therapy experiments conducted Babl/c mice...

10.1371/journal.pone.0043483 article EN cc-by PLoS ONE 2012-08-20

Fucoidan is a sulfated polysaccharide derived from brown algae and known to possess anticancer properties. However, the relationship between fucoidan β-catenin, one of key components Wnt signaling pathway, in mouse breast cancer remains poorly characterized. In this study, cells (4T1) were exposed investigate Wnt/β-catenin pathway vivo vitro. We found that significantly inhibited cell growth, increased death, induced G1 cycle arrest 4T1 cells. also reduced β-catenin expression T...

10.1080/01635581.2013.757628 article EN Nutrition and Cancer 2013-03-26

Geese form a fatty liver after feeding on carbohydrate-rich diet, possibly as an evolutionary adaptation to accumulate reserves for migration. To gain insight into the gene-regulation processes of hepatic steatosis in geese, we examined profile transcriptional expression goose and control by suppression subtractive hybridization measured levels serum biochemical variables. We found 107 genes whose was different between treatment groups. The main functions these are metabolic processes,...

10.3382/ps.2009-00616 article EN cc-by-nc-nd Poultry Science 2010-12-21

This experiment was conducted to evaluate the effects of stocking density on growth performance, feather growth, intestinal development, and serum parameters geese. In total, 336 healthy, 28-day-old, male Yangzhou goslings were randomly allotted 30 plastic wire-floor pens according 5 densities (2, 3, 4, 6 birds/m2). The results showed that with increased from 2 birds/m2 birds/m2, body weights geese at 42 d (P < 0.001) 70 reduced by 10.53% 10.43% respectively, primary lengths = 0.021) 20.38%...

10.3382/ps/pex136 article EN cc-by-nc-nd Poultry Science 2017-06-08

Ghrelin is a multi‑functional peptide, its role on cancer cell apoptosis remains controversial. The present study examined the effects and mechanisms of ghrelin cisplatin‑induced in human breast cells. It was identified that inhibited MDA‑MB‑231 cells vitro reversed expression B‑cell lymphoma 2 (Bcl2) Bcl2‑associated X, cleaved caspase‑3 induced by cisplatin. Furthermore, activated phosphoinositide 3‑kinases/Akt/mammalian target rapamycin (PI3K/Akt/mTOR) signaling pathway after cisplatin...

10.3892/etm.2019.8398 article EN Experimental and Therapeutic Medicine 2019-12-31

Vascular endothelial cell growth factor (VEGF)-C promotes tumorigenesis by allowing lymph node metastasis and lymphangiogenesis, among other actions. RNA interference (RNAi) is a novel technique for suppressing target gene expression may increase the effectiveness of cancer treatments. The present study assessed influence VEGF-C RNAi on apoptosis proliferation mouse breast cells in vitro vivo. A total three pairs small interfering (siRNA) targeting were designed synthesized prior to...

10.3892/ol.2016.5158 article EN Oncology Letters 2016-09-21

Contacting forests in different ways and conducting public perception evaluations of are important to evaluate forest construction. In order explore the differences between on-site manual post-collection indoor landscape surveys, we combined subjective evaluation objective indicator monitoring (eye movement characteristics, physiological indicators) based on observation scales. We compared analyzed suitability following four visual approaches: observation, collection, followed by viewing...

10.3390/f15091566 article EN Forests 2024-09-06

Urban forests are important public recreation sites and play an function in urban biodiversity conservation. Recent studies have found that a beneficial effect on physiological psychological health. Birdsong has good recovery benefits is also the most frequent natural sound. In this paper, blank group, visual perception, audiovisual perception were studied by investigating birds five kinds of simulating their birdsong environment. The results showed following: (1) restorative to public’s...

10.3390/f15122217 article EN Forests 2024-12-16

Enhancing the supply of arginine (Arg), a semi-essential amino acid, has positive effects on immune function in dairy cattle experiencing metabolic stress during early lactation. Our objective was to determine Arg supplementation biomarkers liver damage and inflammation cows Six Chinese Holstein lactating with similar BW (508 ± 14 kg), body condition score (3.0), parity (4.0 0), milk yield (30.6 1.8 kg) days (20 days) were randomly assigned three treatments replicated 3 × Latin square design...

10.1017/s1751731119002106 article EN cc-by-nc-nd animal 2019-10-01
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